Results 181 to 190 of about 14,100 (262)

Identifying interactions between TDP-43's N-terminal and RNA-binding domains. [PDF]

Protein Sci
Scott DD, Jena L, Rajaram A, Ang J, Perez-Miller S, Kumirov V, Khanna R, Khanna M.   +7 more
europepmc   +1 more source

Bemnifosbuvir: An HCV NS5B Inhibitor With Multiple Modes of Action

Clinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 552-562, August 2026.
Bemnifosbuvir (BEM) is a potent, pan‐genotypic inhibitor targeting the hepatitis C virus (HCV) NS5B polymerase. Its antiviral activity was evaluated in an ascending dose phase I clinical trial involving 30 patients treated once a day for 7 days. After treatment initiation, plasma HCV RNA declined in a biphasic manner with a mean reduction of 2.3 log10 ...
Carolin Zitzmann, Ruy M. Ribeiro, Aurélien Marc, Xiao‐Jian Zhou, Alan S. Perelson   +4 more
wiley   +1 more source

Autonomic regulation across sleep and wake during an Antarctic overwintering. [PDF]

Sci Rep
Tortello C, Folgueira A, Cauda B, González LE, Sala Lozano E, Pattyn N, Simonelli G, Plano SA, Vigo DE.   +8 more
europepmc   +1 more source

Real‐world outcomes of responsive neurostimulation in patients with Lennox–Gastaut syndrome: A multicenter retrospective study

Epilepsia Open, Volume 11, Issue 4, Page 1244-1254, August 2026.
Abstract Objective Lennox–Gastaut syndrome (LGS) is a severe developmental and epileptic encephalopathy (DEE) characterized by multiple seizure types and high resistance to antiseizure medication (ASM), often necessitating nonpharmacologic therapies, including neuromodulation.
Shanna M. Swartwood, Robert J. Bollo, Catherine J. Chu, Alexandra L. Geffrey, Robert Mark Richardson, Hiroki Nariai, Aria Fallah, Samuel Ahn, Saadi Ghatan, Laura Chenevert, Maite La Vega‐Talbott, Audie C. Espinoza   +11 more
wiley   +1 more source

A random regression model for total litter weight in mice. [PDF]

J Anim Sci
Jahnel RE, Langhammer M, Reinsch N.
europepmc   +1 more source

Development and Usability Testing of an Information Needs‐Based Chatbot for Individuals With Pathogenic Variants in BRCA Genes in Korea: A Methodological Study

Journal of Genetic Counseling, Volume 35, Issue 4, August 2026.
ABSTRACT Korean individuals with BRCA pathogenic/likely pathogenic (P/LP) variants have limited access to genetic counseling due to shortages of genetic professionals and lack of reimbursement. Despite the growing interest in digital health interventions, few digital counseling support tools have been designed to address the diverse information needs ...
Sun‐Young Park, Youlim Kim, Maria C. Katapodi, Sue Kim   +3 more
wiley   +1 more source

Application of Genomic Random Regression Models for Genetic Parameter Estimations of Female Fertility Traits in Different Parities in German Holsteins. [PDF]

J Anim Breed Genet
Sakhaei-Far S, Yin T, König S.
europepmc   +1 more source

Estimating pediatric lung volumetric parameters via rapid, limited‐slice, free‐breathing thoracic dynamic MRI

Medical Physics, Volume 53, Issue 8, August 2026.
Abstract Background Dynamic, separate lung volume assessment during breathing is critical for evaluating thoracic disorders like scoliosis, thoracic insufficiency syndrome (TIS), and pulmonary diseases, as well as for monitoring treatments. While traditional volumetric assessment relies on static 3D imaging during breath‐holds, this is unfeasible for ...
You Hao, Yubing Tong, Caiyun Wu, Joseph M. McDonough, Samantha Gogel, David M. Biko, Patrick J. Cahill, Jason B. Anari, Drew A. Torigian, Jayaram K. Udupa   +9 more
wiley   +1 more source

CISP, an Intrinsically Disordered Cold-Inducible Barley Protein, Functions as a Small RNA Chaperone. [PDF]

Plant Direct
Okumura Y, Haque MM, Kidou SI.
europepmc   +1 more source

Standard Model Imaging in the Brain and Spinal Cord of MS Patients: Initial Assessment and Comparison to Diffusion Tensor Imaging

NMR in Biomedicine, Volume 39, Issue 8, August 2026.
DTI and SMIfw diffusion models applied in persons with multiple sclerosis revealed region‐specific sensitivity to microstructural injury, but performance differed by anatomical region. SMIfw neurite density fraction demonstrated high sensitivity and reliability in both the brain and spinal cord, whereas DTI measures such as fractional anisotropy and ...
Atlee Witt, Alicia E. Cronin, Bailey Busher, Isabella Stuart, Grace Sweeney, Kristin P. O'Grady, Seth A. Smith, Samantha By, Kurt Schilling   +8 more
wiley   +1 more source