Results 131 to 140 of about 508,064 (311)

Groundtruthing next-gen sequencing for microbial ecology-biases and errors in community structure estimates from PCR amplicon pyrosequencing

, 2012
Analysis of microbial communities by high-throughput pyrosequencing of SSU rRNA gene PCR amplicons has transformed microbial ecology research and led to the observation that many communities contain a diverse assortment of rare taxa-a phenomenon termed ...
Polson, Shawn W., Shawn W. Polson (139348), Craig W. Herbold (139346), Charles K Lee, Ian R McDonald, S Craig Cary, K Eric Wommack, K. Eric Wommack (139352), Charles K. Lee (139341), Ian R. McDonald (139355), Herbold, Craig W., Lee, Charles Kai-Wu, Shawn W Polson, Shannon J. Williamson (38225), Williamson, Shannon J., Cary, S. Craig, S. Craig Cary (133811), Craig W Herbold, Shannon J Williamson, McDonald, Ian R., Wommack, K. Eric   +20 more
core   +1 more source

A Chirality‐Converted Bacteriolytic Dodecapeptide Regulates Vibrio‐Induced Polymicrobial Infection and Ameliorates Invasion‐Associated Gut Microbiota Disequilibrium

Advanced Science, EarlyView.
Multidrug‐resistant Vibrio infections are rising rapidly and threaten coastal populations worldwide. This study introduces D‐zp37, a chirality‐engineered antimicrobial peptide with exceptional potency against resistant Vibrio species. D‐zp37 kills planktonic cells, blocks mixed‐species biofilms, disrupts essential bacterial stress responses, and shows ...
Ping Zeng, Qipeng Cheng, Xiaoxu Zhang, Honglan Wang, Jinghan Zhang, Xinyi Ding, Pengfei Zhang, Lanhua Yi, Kwok‐Yin Wong, Kin‐Fai Chan, Sheng Chen, Sharon Shui Yee Leung   +11 more
wiley   +1 more source

SuhB Associates with Nus Factors To Facilitate 30S Ribosome Biogenesis in Escherichia coli

mBio, 2016
A complex of highly conserved proteins consisting of NusB, NusE, NusA, and NusG is required for robust expression of rRNA in Escherichia coli.
Navjot Singh, Mikhail Bubunenko, Carol Smith, David M. Abbott, Anne M. Stringer, Ronald Shi, Donald L. Court, Joseph T. Wade   +7 more
doaj   +1 more source

MFPD: A Multiple Fungal Pathogen Detection Pipeline Across Diverse Habitats

Advanced Science, EarlyView.
The MFPD pipeline integrates a comprehensive ITS reference database of fungal pathogens, optimized parameters, and algorithms tailored for both full‐length and subregion sequences that balance accuracy and computational efficiency; it enables high‐throughput, species‐level identification from amplicon sequencing data, supporting large‐scale ...
Yi Shen, Xinrun Yang, Jiabao Yu, Yaozhong Zhang, Tianjie Yang, Yang Gao, Xiaofang Wang, Alexandre Jousset, Waseem Raza, Fang‐Jie Zhao, Qirong Shen, Gaofei Jiang, Zhong Wei, Yangchun Xu   +13 more
wiley   +1 more source

rRNA—the evolution of that magic molecule [PDF]

RNA, 2015
I was delighted when Tim Nilsen asked me to contribute an article for this special 20th anniversary issue. I've been very fortunate to witness and participate in the transformation of our understanding of RNA and the biology that is emerging because of it.
openaire   +2 more sources

Monoallelically expressed noncoding RNAs form nucleolar territories on NOR-containing chromosomes and regulate rRNA expression

eLife
Out of the several hundred copies of rRNA genes arranged in the nucleolar organizing regions (NOR) of the five human acrocentric chromosomes, ~50% remain transcriptionally inactive.
Qinyu Hao, Minxue Liu, Swapna Vidhur Daulatabad, Saba Gaffari, You Jin Song, Rajneesh Srivastava, Shivang Bhaskar, Anurupa Moitra, Hazel Mangan, Elizabeth Tseng, Rachel B Gilmore, Susan M Frier, Xin Chen, Chengliang Wang, Sui Huang, Stormy Chamberlain, Hong Jin, Jonas Korlach, Brian McStay, Saurabh Sinha, Sarath Chandra Janga, Supriya G Prasanth, Kannanganattu V Prasanth   +22 more
doaj   +1 more source

Amuc_1473 Links Gut Microbes to Skeletal Homeostasis and Counteracts Multifactorial Osteoporosis

Advanced Science, EarlyView.
Amuc_1473, a previously uncharacterized protein enriched in Akkermansia muciniphila‐derived extracellular vesicles, is identified as a gut–bone messenger that promotes osteogenesis and inhibits osteoclastogenesis by engaging transcriptional and translational regulators in bone cells.
Shan‐Shan Rao, Hai‐Jin Zeng, Zun Wang, Chun‐Gu Hong, Yi‐Juan Tan, Yan‐Xin Duan, Jing‐Yao Luo, Ming‐Jie Luo, Yi‐Wei Liu, Xin Wang, Yi Luo, Teng‐Fei Wan, Yong Zhou, Zheng‐Guang Wang, Guo‐Wen Hu, Hao Yin, Xin‐Yue Hu, Zhen‐Xing Wang, Ze‐Hui He, Si‐Yi Cheng, Wei Du, Zhe Guan, Hai‐Li Lang, Hong‐Ji Liu, Jia Cao, Peng Chen, Jiang‐Hua Liu, Hui Xie, Chun‐Yuan Chen   +28 more
wiley   +1 more source

Chitosan‐Carbon Dot Composite Materials Form a Leaf Surface Barrier to Mitigate the Enrichment and Invasion of Nanoplastics: From Leaf Interface to Systemic Response

Advanced Science, EarlyView.
Foliar spraying of CS‐CDs can form a film on the leaves of Brassica rapa, effectively reducing the enrichment and absorption of PS in the leaves, while increasing the biomass and nutrient content of the plants. In addition, CS‐CDs can also enrich the interfoliar microbial community and activate the plant's own defense metabolic pathways.
Beibei Zhao, Mei Li, Mengjiao Fan, Chuanhuan Liu, Jie Jiang, Jia Song, Yingzhu Liu   +6 more
wiley   +1 more source

Comparison of bacterial culture and 16S rRNA community profiling by clonal analysis and pyrosequencing for the characterization of the dentine caries-associated microbiome

, 2014
Culture-independent analyses have greatly expanded knowledge regarding the composition of complex bacterial communities including those associated with oral diseases.
Kathrin eSchulze-Schweifing, Avijit eBanerjee, Wade, William G, Banerjee, A, Schulze-Schweifing, K, Schulze-Schweifing, Kathrin, Wade, WG, Banerjee, Avijit; id_orcid, William Geoffrey Wade, William G. Wade, Kathrin Schulze-Schweifing, Avijit Banerjee   +11 more
core   +1 more source

A Dual‐Functional Biohybrid Nanorobot to Synergistically Eradicate Biofilm and Degrade Antibiotic Resistance Genes

Advanced Science, EarlyView.
A biohybrid nanorobot integrating lytic bacteriophage N4 with Pd nanozymes is developed for targeted eradication of multidrug‐resistant E. coli biofilms. Synergistic bacterial lysis and ROS‐mediated oxidation enable simultaneous biofilm removal and antibiotic resistance genes degradation, maintaining high efficacy in complex wastewater environments ...
Junzheng Zhang, Tong Dou, Luokai Wang, Jingxian Yang, Wenrui Wang, Shuaitian Guo, Xiangyu Li, Xuefang Huang, Yunlei Xianyu, Dongsheng Wang   +9 more
wiley   +1 more source