Results 271 to 280 of about 718,346 (357)

Interleukin‐2 Deprived State of Regulatory T cells and Their Recovery by Low‐Dose Interleukin‐2 in Patients With Inflammatory Myopathies

Arthritis &Rheumatology, EarlyView.
Objective Regeneration and expansion of Treg by low‐dose interleukin‐2 (IL‐2) therapy is considered a potential treatment strategy for a wide range of autoimmune diseases. To provide a pathophysiologically‐based rationale for low‐dose IL‐2 therapy, we investigated whether reversible defects in the Treg–IL‐2 axis emerge in inflammatory myopathies ...
Justus Ohmes, Luisa R. Monne, Sara Comdühr, Fynn Gerlach, Hanna Grasshoff, Alexander Dübbers, Antje Müller, Alexander Scheffold, Gabriela Riemekasten, Reza Akbarzadeh, Jens Y. Humrich   +10 more
wiley   +1 more source

Age- and region-specific gut microbiota dysbiosis in axial spondyloarthritis: a systematic review and meta-analysis. [PDF]

Front Immunol
Liu L, Yin L, Liu Z, Xu M, Kong F, Zheng Y.   +5 more
europepmc   +1 more source

Clock genes regulate Ca2+ signaling and mitochondrial bioenergetics to inhibit Sjogren's disease

Arthritis &Rheumatology, Accepted Article.
Objective Although Ca2+ signaling and metabolism have been identified as key determinants for the development of Sjogren's disease (SjD), the intricate connection between them and salivary gland physiology remains poorly understood. Methods Fluorescence‐based Ca2+ imaging, RNA seq, and mitochondrial activity were used to investigate the effects of ...
Viktor R. Drel, Manigandan Venkatesan, Rahul S. Jasrotia, Yuyang Sun, Viviane Nascimento Da Conceicao, Neelanjan Vishnu, Shankara N Varadarajan, Venugopal R. Bovilla, Rajender K Motiani, Shobhan Gaddameedhi, Bibhuti B. Mishra, Muniswamy Madesh, Brij B. Singh   +12 more
wiley   +1 more source

Ribosomal modifications are associated with mesenchymal fate selection in the neural crest lineage. [PDF]

Nat Commun
Poverennaya I, Murtazina A, Li L, Maili L, Sourada L, Montano-Gutierrez LF, Galimullina R, Steinschaden T, Kaiser M, Zikmund T, Goralija A, Gao T, Attina A, Clara O, Bartenhagen C, Erickson A, Gershtein Y, Chen S, Polaskova K, Sterba J, Semasch B, Anderson ER, Prakash V, Vincent T, Arceo M, Kogner P, Schlisio S, Kharchenko PV, David A, Kaiser J, Fischer M, Skoda J, Trainor PA, Chagin AS, Adameyko I.   +34 more
europepmc   +1 more source

Bioprospecting Ulleungdo‐isolated microalgae for carbon valorization and utilization

Biofuels, Bioproducts and Biorefining, EarlyView.
Abstract The growing demand for renewable energy alternatives has intensified global interest in microalgae as versatile bioresources for carbon valorization and bioenergy production. Owing to their rapid growth and biochemical versatility, microalgae provide a sustainable route for converting captured carbon into bioenergy and high‐value products ...
Ha‐Neul Choi, Jeong‐Mi Do, Su‐Bin Park, Myeong‐Jun Gwon, Geum‐Sook Do, Ho‐Sung Yoon   +5 more
wiley   +1 more source

Complete genome sequence of <i>Sedimentibacter</i> sp. strain MB31-C6, isolated from sewage sludge. [PDF]

Microbiol Resour Announc
Zhang H, Zhang J, Li Y, Yang L, Shih C-J, Wu Y-C, Chen S-C.   +6 more
europepmc   +1 more source

Production of bacterial cellulose by Acetobacter okinawensis AC2 and its application as a bioadsorbent for azo dye removal

Biofuels, Bioproducts and Biorefining, EarlyView.
Abstract Bacterial cellulose (BC) is a naturally occurring polysaccharide that has attracted considerable interest in various fields, including biological and biomedical applications, due to its biodegradability, biocompatibility, high degree of crystallinity, and outstanding physicochemical characteristics. It is widely used in several industries such
Mehmet Akif Omeroglu, Neslihan Keles, Mesut Taskin   +2 more
wiley   +1 more source

The novel genus Brakhagea gen. nov. is constituted by four planctomycetal species isolated from aquatic environments in Northern Germany. [PDF]

Sci Rep
Kumar G, Kallscheuer N, Hammer J, Haufschild T, Jogler C.   +4 more
europepmc   +1 more source

Deciphering the catalytic and pharmacological mechanisms of Coptis chinensis herbzymes to renovate intestinal microenvironment for colitis alleviation

BMEMat, EarlyView.
The synthesized CCzymes possess both antioxidant enzyme activity and pharmacological properties inherent to Coptis chinensis. By their antioxidant enzyme activity, CCzymes can attenuate oxidative stress within the inflammatory region of ulcerative colitis (UC), while their pharmacological activity acts on macrophage polarization and the intestinal ...
Zhichao Deng, Can Li, Yujie Zhang, Yuanyuan Zhu, Chenxi Xu, Bowen Gao, Mingxin Zhang, Martina H. Stenzel, Kelong Fan, Mingzhen Zhang, Yanyan Jiang   +10 more
wiley   +1 more source