Results 41 to 50 of about 696,870 (312)

Endonucleolytic processing plays a critical role in the maturation of ribosomal RNA in Methanococcus maripaludis

open access: yesRNA Biology, 2023
Ribosomal RNA (rRNA) processing and maturation are fundamentally important for ribosome biogenesis, but the mechanisms in archaea, the third form of life, remains largely elusive.
Lei Qi   +6 more
doaj   +1 more source

Reconciliation between operational taxonomic units and species boundaries [PDF]

open access: yes, 2017
The development of high-throughput sequencing technologies has revolutionised the field of microbial ecology via 16S rRNA gene amplicon sequencing approaches.
Boon, Nico   +7 more
core   +2 more sources

A working model for cytoplasmic assembly of H/ACA snoRNPs

open access: yesFEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source

Identification of an Alternative rRNA Post-transcriptional Maturation of 26S rRNA in the Kingdom Fungi

open access: yesFrontiers in Microbiology, 2018
Despite of the integrity of their RNA, some desert truffles present a non-canonical profile of rRNA where 3.3 kb is absent, 1.8 kb is clear and a band of 1.6 kb is observed.
Alfonso Navarro-Ródenas   +2 more
doaj   +1 more source

Progenitor‐derived ribosomal RNA supports protein synthesis in Drosophila neurons

open access: yesNatural Sciences, 2022
Global mRNA translation may differ dramatically between progenitor cells and their differentiated progeny. One way cell type‐specific translation is established is through ribosome concentration.
Jade Fee   +2 more
doaj   +1 more source

Multiple prebiotic metals mediate translation. [PDF]

open access: yes, 2018
Today, Mg2+ is an essential cofactor with diverse structural and functional roles in life's oldest macromolecular machine, the translation system. We tested whether ancient Earth conditions (low O2, high Fe2+, and high Mn2+) can revert the ribosome to a ...
Bowman, Jessica C   +8 more
core   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

The Regulation of rRNA Gene Transcription during Directed Differentiation of Human Embryonic Stem Cells. [PDF]

open access: yesPLoS ONE, 2016
It has become increasingly clear that proper cellular control of pluripotency and differentiation is related to the regulation of rRNA synthesis. To further our understanding of the role that the regulation of rRNA synthesis has in pluripotency we ...
Jessica L Woolnough   +4 more
doaj   +1 more source

The Human Oral Microbiome Database: a web accessible resource for investigating oral microbe taxonomic and genomic information [PDF]

open access: yes, 2010
The human oral microbiome is the most studied human microflora, but 53% of the species have not yet been validly named and 35% remain uncultivated. The uncultivated taxa are known primarily from 16S rRNA sequence information.
Baranova, Oxana V.   +5 more
core   +1 more source

High-throughput sequencing of 16S rRNA gene amplicons : effects of extraction procedure, primer length and annealing temperature [PDF]

open access: yes, 2012
The analysis of 16S-rDNA sequences to assess the bacterial community composition of a sample is a widely used technique that has increased with the advent of high throughput sequencing.
Cogan, Tristan   +4 more
core   +3 more sources

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