Results 61 to 70 of about 193,324 (261)
Background NOL12 5′-3′ exoribonucleases, conserved among eukaryotes, play important roles in pre-rRNA processing, ribosome assembly and export. The most well-described yeast counterpart, Rrp17, is required for maturation of 5.8 and 25S rRNAs, whereas ...
Monika Zakrzewska-Placzek +5 more
doaj +1 more source
The Lactobacillaceae are lactic acid bacteria harnessed to deliver important outcomes across numerous industries, and their unambiguous, species-level identification from mixed community environments is an important endeavor.
Sandra A. Olivier +9 more
doaj +1 more source
40S ribosome biogenesis co-factors are essential for gametophyte and embryo development [PDF]
Ribosome biogenesis is well described in Saccharomyces cerevisiae. In contrast only very little information is available on this pathway in plants. This study presents the characterization of five putative protein co-factors of ribosome biogenesis in ...
Roman Martin +22 more
core +2 more sources
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Locus-specific ribosomal RNA gene silencing in nucleolar dominance. [PDF]
The silencing of one parental set of rRNA genes in a genetic hybrid is an epigenetic phenomenon known as nucleolar dominance. We showed previously that silencing is restricted to the nucleolus organizer regions (NORs), the loci where rRNA genes are ...
Michelle S Lewis +4 more
doaj +1 more source
PCR biases distort bacterial and archaeal community structure in pyrosequencing datasets [PDF]
As 16S rRNA gene targeted massively parallel sequencing has become a common tool for microbial diversity investigations, numerous advances have been made to minimize the influence of sequencing and chimeric PCR artifacts through rigorous quality control ...
Lutgarde Raskin (143205) +7 more
core +2 more sources
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Progenitor‐derived ribosomal RNA supports protein synthesis in Drosophila neurons
Global mRNA translation may differ dramatically between progenitor cells and their differentiated progeny. One way cell type‐specific translation is established is through ribosome concentration.
Jade Fee +2 more
doaj +1 more source
Mapping of the Chemical Modifications of rRNAs
AbstractCellular RNAs, both coding and noncoding, contain several chemical modifications. Both ribose sugars and nitrogenous bases are targeted for these chemical additions. These modifications are believed to expand the topological potential of RNA molecules by bringing chemical diversity to otherwise limited repertoire.
Jun, Yang +2 more
openaire +2 more sources
nf-core/rrna-ampliseq: rrna-ampliseq V1.0.0 "Olive Steel Panda"
<p>This is the initial stable release of rrna-ampliseq V 1.0.0 "Olive Steel Panda".</p> <p>This repository follows <a href="https://semver.org/">semantic versioning</a> guidelines to push new releases once available. We will
d4straub, Alexander Peltzer
core +1 more source

