Results 31 to 40 of about 110,334 (168)

Hypericum perforatum Alleviates Ovalbumin-Induced Asthma through Downregulating TH2 and Upregulating TH1 Related Parameters in BALB/C Mice [PDF]

Pharmaceutical Sciences
Background: Allergic asthma is a chronic and inflammatory disease of the respiratory tract, which is characterized by inflammation, airway obstruction and swelling. Anti-inflammatory compounds can be used to improve the disease severity.
Fahimeh Rostamabadi, Reza Nosratabadi, Amir Rahnama, Vahid Mohammadi-Shahrokhi   +3 more
doaj   +1 more source

Retinal organoids with X-linked retinoschisis RS1 (E72K) mutation exhibit a photoreceptor developmental delay and are rescued by gene augmentation therapy

Stem cell research & therapeutics
X-linked juvenile retinoschisis (XLRS) is an inherited disease caused by RS1 gene mutation, which leads to retinal splitting and visual impairment. The mechanism of RS1-associated retinal degeneration is not fully understood.
Chunwen Duan, C. Ding, Xihao Sun, Shengru Mao, Yuqin Liang, Xinyu Liu, X. Ding, Jiansu Chen, Shibo Tang   +8 more
semanticscholar   +1 more source

Comparison of MnCo2O4 coated Crofer 22 H, 441, 430 as interconnects for intermediate-temperature solid oxide fuel cell stacks

, 2020
The low-cost ferritic steel grades 441 and 430 are benchmarked against the specialty grade Crofer 22H as possible interconnect materials for intermediate temperature solid oxide fuel cells. The steels are either pre-oxidized or coated with MnCo2O4.
B. Talic, V. Venkatachalam, P. Hendriksen, R. Kiebach   +3 more
semanticscholar   +1 more source

Unveiling the Biomedical Applications of Zinc Oxide (ZnO) Nanoparticles: A Review Fostering on the Synthesis, Therapeutics and Imaging with Recent Developments [PDF]

Pharmaceutical Sciences
Zinc oxide nanoparticles (ZnO-NPs) in their many formulations have prompted an immense interest in nanomedicine and drug development. Numerous ZnO-NPs bioactive formulations demonstrate remarkable broad applications in deciphering their therapeutic ...
Zenli Cheng, Ashok Kumar Janakiraman, Baskaran Gunasekaran, Crystale Lim Siew Ying, Ezanee Azlina Binti Mohamad Hanif, Hanish Singh Jayasingh Chellammal, Sinouvassane Djearamane   +6 more
doaj   +1 more source

Kir4.1 and Aqp4 Contribution to Schisis Cystic Water Accumulation and Clearance in the Rs1 Exon-1 Del XLRS Rat Model

Genes
Background/Objective: The Rs1 exon-1-del rat (Rs1KO) XLRS model shows normal retinal development until postnatal day 12 (P12) when small cystic spaces start to form in the inner nuclear layer.
Zeljka Smit-McBride, Ning Sun, Serafina Thomas, In Hwan Cho, Robin G. Stricklin, P. Sieving   +5 more
semanticscholar   +1 more source

Establishment of a human induced pluripotent stem cell line (CSUASOi005-A), from peripheral blood mononuclear cells of a patient with X-linked juvenile retinoschisis carrying a novel mutation in RS1 gene.

Stem Cell Research, 2020
X-linked retinoschisis (XLRS) is a one of most common retinal genetic diseases of juvenile progressive vitreoretinal degeneration in males, which caused by the mutation of RS1 gene.
Shengru Mao, C. Ding, Yalan Zhou, Yutong Jing, Juan Chen, Yonglong Guo, Jian Liu, Zekai Cui, Xin Yan, Jianing Gu, Yini Wang, Jiansu Chen, Shibo Tang   +12 more
semanticscholar   +1 more source

Can L-Carnitine Replace Tumor Necrosis Factor-Alpha Blockers? A Systematic Review and Dose–Response Meta-Analysis [PDF]

Pharmaceutical Sciences
Background: L-carnitine (LC), an amino acid-like molecule, has been shown to reduce tumor necrosis factor-alpha (TNF-α), although some research has not confirmed its impact.
Farnaz Naeimzadeh, Amirreza Naseri, Sarvin Sanaie, Seiedhadi Saghaleini, Afshin Gharekhani   +4 more
doaj   +1 more source

Long-term (4 year) degradation behavior of coated stainless steel 441 used for solid oxide fuel cell interconnect applications

Journal of Power Sources, 2020
The present work aims to investigate the long-term stability of Ce/Co coated AISI 441 used as an interconnect material in solid oxide fuel cells (SOFC).
C. Goebel, R. Berger, Carlos Bernuy-Lopez, J. Westlinder, J. Svensson, J. Froitzheim   +5 more
semanticscholar   +1 more source

Novel mutations in the RS1 gene in Japanese patients with X-linked congenital retinoschisis

Human Genome Variation, 2019
X-linked congenital retinoschisis (XLRS) is an inherited retinal disorder characterized by reduced central vision and schisis of the macula and peripheral retina. XLRS is caused by mutations in the RS1 gene.
H. Kondo, Kazuma Oku, S. Katagiri, T. Hayashi, T. Nakano, Akiko Iwata, K. Kuniyoshi, S. Kusaka, Atsushi Hiyoshi, E. Uchio, M. Kondo, N. Oishi, S. Kameya, A. Mizota, N. Naoi, S. Ueno, H. Terasaki, T. Morimoto, M. Iwaki, K. Yoshitake, D. Iejima, K. Fujinami, K. Tsunoda, K. Shinoda, T. Iwata   +24 more
semanticscholar   +1 more source

Caesalpinia sappan reduces the stemness of breast cancer stem cells involving the elevation of intracellular reactive oxygen species

Research in Pharmaceutical Sciences, 2023
Background and purpose: Breast cancer stem cells (BCSCs) as a kind of tumor cells are able to regenerate themselves, leading to apoptosis resistance and cancer relapse.
Riris Istighfari Jenie, Nur Dina Amalina, Adam Hermawan, Meiny Suzery, Agung Putra, Edy Meiyanto   +5 more
doaj   +1 more source