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Association of variable rs1801282 locus of PPARG2 gene with diabetic nephropathy

Russian Journal of Genetics, 2016
The association of the variable rs1801282 locus of the PPARG2 gene (peroxisome proliferator-activated receptor gamma) with type 2 diabetes mellitus and its complications was analyzed in inhabitants of the Republic of Bashkortostan. The genotype frequencies of the variable rs1801282 locus of the PPARG2 gene did not significantly differ in groups of ...
Vera Erdman   +2 more
exaly   +3 more sources

Association of Pro12Ala (rs1801282) variant of PPAR gamma with Rheumatoid Arthritis in a Pakistani population

Rheumatology International, 2013
Peroxisome proliferator-activated receptor-gamma (PPAR-gamma) belongs to a receptor superfamily of ligand-activated transcription factors, encoded by PPARG gene. Role of PPARγ has been well established in variety of metabolic disorders and in regulation of inflammation.
Peter John   +2 more
exaly   +3 more sources

Evaluation of the involvement of PPARG2 gene rs1801282 polymorphism in the pathogenesis of bronchial asthma with obesity in children

Bulletin Physiology and Pathology of Respiration, 2022
Introduction. Features of the clinical course of bronchial asthma in children with obesity made it possible to identify a special phenotype, when the presence and severity of obesity determine a more severe course of asthma and a worse response to asthma therapy. Asthma, like obesity, is recognized as a classic example of multifactorial diseases, which
R. S. Telepneva   +6 more
openaire   +1 more source

Geographic diversity in genotype frequencies and meta-analysis of the association between rs1801282 polymorphisms and gestational diabetes mellitus

Diabetes Research and Clinical Practice, 2018
To derive a better understanding of the association between peroxisome proliferator-activated receptor gamma (PPAR-γ) rs1801282 polymorphisms and gestational diabetes mellitus (GDM) in general and in racial and ethnic subgroups and to illustrate geographic distribution of the protective of G allele of rs1801282 in women with and without GDM.ProQuest ...
Piling Chou, Lin Pei-Chao
exaly   +3 more sources

Biochemical investigation of rs1801282 variations in PPAR‐γ gene and its correlation with risk factors of diabetes mellitus in coronary artery disease

Clinical and Experimental Pharmacology and Physiology, 2020
Abstract We aimed to investigate the association of single nucleotide polymorphism of Pro/Ala (rs1801282) in peroxisome proliferator‐activated receptor‐gamma (PPAR‐γ) gene with risk factors of diabetes mellitus (DM) in cardiovascular disease (CVD) patients.
Kanwal Rehman   +2 more
exaly   +3 more sources

FTO (rs9939609), FABP2 (rs1799883), and PPARG (rs1801282) gene polymorphisms and obesity risk in men living in Kuzbass

Nauchno-prakticheskii zhurnal «Medicinskaia genetika, 2022
Цель: изучение ассоциаций полиморфизма генов FTO, FABP2, PPARG и ожирения у жителей Кузбасса. Методы. Выборка для исследования составила 395 мужчин, жителей Кузбасса. Средний возраст испытуемых составил 59±7,7 года. Согласно анкетным данным, все обследованные мужчины отнесли себя к русской национальности. Частота ожирения в данной выборке (индекс массы
openaire   +1 more source

Lack of genetic associations between PPAR-γ gene rs1801282 polymorphism and Alzheimer's disease in general population: A meta-analysis

Gene, 2015
Published studies have evaluated the association between PPAR-γ rs1801282 polymorphism and Alzheimer's disease (AD) susceptibility. However, a definitive conclusion remains elusive. The aim of this study was to derive a more precise estimation of this association.
Yongfu Wu, Yang Huiling
exaly   +3 more sources

Genetic association of PPARG gene polymorphism (rs1801282) with susceptibility to Chronic periodontitis

International Journal of Drug Delivery Technology
Introduction: Periodontitis is defined by pathologic loss of the periodontal ligament and alveolar bone. The disease involves complex dynamic interactions among active herpesviruses, specific bacterial pathogens and destructive immune responses. Periodontal diagnostics is currently based on clinical rather than etiologic criteria, and provides limited ...
Chandan Panigrahi   +4 more
openaire   +1 more source

Association of PPARG (rs1801282) genetic polymorphism and obesity with T2DM: A study on Bengalee Hindu caste population of West Bengal, India

Meta Gene, 2020
Abstract Peroxisome Proliferator-Activated Receptors gamma (PPARG) are widely known to substantiate their role in T2DM and T2DM complications. The study was conducted to understand the association of PPARG (rs1801282) genetic polymorphisms and obesity with T2DM in Bengalee Hindu caste population of West Bengal, India.
Pranabesh Sarkar   +2 more
openaire   +1 more source

Prevalence of PPAR-γ2 (rs1801282), RETN (rs3745367) and ADIPOQ (rs2241766) SNP markers in the Bangladeshi type 2 diabetic population

Meta Gene, 2016
Abstract The genetic variants within peroxisome-proliferator activated receptor-gamma 2 (rs1801282), resistin (rs3745367) and adiponectin (rs2241766) were examined in this pilot study to find a possible link between the single nucleotide polymorphisms (SNPs) and type 2 diabetes mellitus (T2D) in the Bangladeshi population.
Hasan Mahmud Reza, Masashi Kawaichi
exaly   +2 more sources

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