Results 121 to 130 of about 1,303 (153)

The Effect Sizes of PPARγ rs1801282, FTO rs9939609, and MC4R rs2229616 Variants on Type 2 Diabetes Mellitus Risk among the Western Saudi Population: A Cross-Sectional Prospective Study

Genes, 2020
Type 2 diabetes mellitus (T2DM) is a common polygenic disease with associated comorbidities. Obesity is a major risk factor for the development of T2DM.
Rami Nassir, Rana M Altall, Ashraf Dallol   +2 more
exaly   +2 more sources

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Association of variable rs1801282 locus of PPARG2 gene with diabetic nephropathy

Russian Journal of Genetics, 2016
The association of the variable rs1801282 locus of the PPARG2 gene (peroxisome proliferator-activated receptor gamma) with type 2 diabetes mellitus and its complications was analyzed in inhabitants of the Republic of Bashkortostan. The genotype frequencies of the variable rs1801282 locus of the PPARG2 gene did not significantly differ in groups of ...
Tatyana Morugova, Vera V Erdman, Olga Mustafina   +2 more
exaly   +3 more sources

Geographic diversity in genotype frequencies and meta-analysis of the association between rs1801282 polymorphisms and gestational diabetes mellitus

Diabetes Research and Clinical Practice, 2018
To derive a better understanding of the association between peroxisome proliferator-activated receptor gamma (PPAR-γ) rs1801282 polymorphisms and gestational diabetes mellitus (GDM) in general and in racial and ethnic subgroups and to illustrate geographic distribution of the protective of G allele of rs1801282 in women with and without GDM.ProQuest ...
Pi-Ling Chou, Pei-Chao Lin
exaly   +3 more sources

Evaluation of the involvement of PPARG2 gene rs1801282 polymorphism in the pathogenesis of bronchial asthma with obesity in children

Bulletin Physiology and Pathology of Respiration, 2022
Introduction. Features of the clinical course of bronchial asthma in children with obesity made it possible to identify a special phenotype, when the presence and severity of obesity determine a more severe course of asthma and a worse response to asthma therapy. Asthma, like obesity, is recognized as a classic example of multifactorial diseases, which
R. S. Telepneva, G. P. Evseeva, E. В. Nagovitsyna, E. N. Suprun, N. I. Khaletskaya, S. V. Suprun, O. A. Lebedko   +6 more
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Quantitative evaluation of common polymorphism (rs1801282) in the PPARγ2 gene and hypertension susceptibility

Gene, 2012
The peroxisome proliferator-activated receptor-γ2 (PPARγ2) gene has been implicated in the etiology of hypertension. However, the results have been inconsistent. In this study, a meta-analysis was performed to assess the association of PPARγ2 rs1801282 polymorphism with hypertension risk.
Yujun, Wang, Chibo, Liu
openaire   +2 more sources

Association of Pro12Ala (rs1801282) variant of PPAR gamma with Rheumatoid Arthritis in a Pakistani population

Rheumatology International, 2013
Peroxisome proliferator-activated receptor-gamma (PPAR-gamma) belongs to a receptor superfamily of ligand-activated transcription factors, encoded by PPARG gene. Role of PPARγ has been well established in variety of metabolic disorders and in regulation of inflammation.
Syed Fazal, Jalil, Iltaf, Ahmed, Zeeshan, Gauhar, Mushtaq, Ahmed, Javaid M, Malik, Peter, John, Attya, Bhatti   +6 more
openaire   +2 more sources

Biochemical investigation of rs1801282 variations in PPAR-γ gene and its correlation with risk factors of diabetes mellitus in coronary artery disease

Clinical and Experimental Pharmacology and Physiology, 2020
Abstract We aimed to investigate the association of single nucleotide polymorphism of Pro/Ala (rs1801282) in peroxisome proliferator‐activated receptor‐gamma (PPAR‐γ) gene with risk factors of diabetes mellitus (DM) in cardiovascular disease (CVD) patients.
Kanwal Rehman, Misbah Hussain, Fazli Rabbi Awan   +2 more
exaly   +3 more sources

The Protective Effect of G-Allele of PPARG2 rs1801282 Polymorphism Against Overweight and Obesity in Mongoloid Adolescents

Journal of Medical and Biological Research, 2019
Kseniya D. Ievleva, Tat’yana A. Bairova, Ekaterina A. Sheneman, Evgeniya A. Novikova, Ol’ga V. Bugun, Lyubov’ V. Rychkova, Lyubov’ I. Kolesnikova, Zhanna G. Ayurova, Varvara V. Bal’zhieva   +8 more
exaly   +2 more sources

FTO (rs9939609), FABP2 (rs1799883), and PPARG (rs1801282) gene polymorphisms and obesity risk in men living in Kuzbass

Nauchno-prakticheskii zhurnal «Medicinskaia genetika, 2022
Цель: изучение ассоциаций полиморфизма генов FTO, FABP2, PPARG и ожирения у жителей Кузбасса. Методы. Выборка для исследования составила 395 мужчин, жителей Кузбасса. Средний возраст испытуемых составил 59±7,7 года. Согласно анкетным данным, все обследованные мужчины отнесли себя к русской национальности. Частота ожирения в данной выборке (индекс массы
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Genetic association of PPARG gene polymorphism (rs1801282) with susceptibility to Chronic periodontitis

International Journal of Drug Delivery Technology
Introduction: Periodontitis is defined by pathologic loss of the periodontal ligament and alveolar bone. The disease involves complex dynamic interactions among active herpesviruses, specific bacterial pathogens and destructive immune responses. Periodontal diagnostics is currently based on clinical rather than etiologic criteria, and provides limited ...
Chandan Panigrahi, Karthikeyan Murthykumar, Vijayashree Priyadharshini, Dhanraj Ganapathy, Marina Marina   +4 more
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