Results 101 to 110 of about 2,006 (194)

The profile of selected single nucleotide polymorphisms in patients with hypertension and heart failure with preserved and mid-range ejection fraction

Scientific Reports, 2017
The study aimed to assess the clinical significance of selected single nucleotide polymorphisms (SNPs) in patients with diastolic heart failure (HF): inflammation [-174 G/C Interleukin -6 (IL-6) rs1800795, tumor necrosis factor (TNF)-608 G/A rs1800629 ...
Agata Bielecka-Dabrowa, Agata Sakowicz, Tadeusz Pietrucha, Małgorzata Misztal, Piotr Chruściel, Jacek Rysz, Maciej Banach   +6 more
doaj   +1 more source

Genetic variation at the CY2C19 gene associated with Metabolic Syndrome susceptibility in a South Portuguese population [PDF]

, 2013
Metabolic syndrome (MetS) is a cluster of conditions — increased blood pressure, high blood glucose level, excess body fat around the waist and abnormal cholesterol levels — that occur together, increasing the risk of heart disease, stroke and diabetes ...
Barreto da Silva, Marta, Beleza, Álvaro, Bourbon, Mafalda, Dias, Carlos Matias, Fernandes, Aida, Gaio, Vania, Gil, Ana Paula, Horta Correia, Filomena, Mendonça, Francisco, Nunes, Baltazar, Vicente, A.M.   +10 more
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Molecular Analysis of a Genetic Variants Panel Related to Nutrients and Metabolism: Association with Susceptibility to Gestational Diabetes and Cardiometabolic Risk in Affected Women

Journal of Diabetes Research, 2017
Gestational diabetes mellitus (GDM) is the most frequent metabolic disorder in pregnancy. Women with a GDM history are at increased risk of developing diabetes and cardiovascular diseases.
Marica Franzago, Federica Fraticelli, Antonio Nicolucci, Claudio Celentano, Marco Liberati, Liborio Stuppia, Ester Vitacolonna   +6 more
doaj   +1 more source

Association between 28 single nucleotide polymorphisms and type 2 diabetes mellitus in the Kazakh population: a case-control study. [PDF]

, 2017
We evaluated the associations between single nucleotide polymorphisms and different clinical parameters related to type 2 diabetes mellitus (T2DM), obesity risk, and metabolic syndrome (MS) in a Kazakh cohort. A total of 1336 subjects, including 408 T2DM
Eap, C.B., Iskakova, A., Ramanculov, E., Saigi-Morgui, N., Sikhayeva, N., Zholdybaeva, E.   +5 more
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A meta-analysis of the association of PPARγ rs1801282 polymorphism and NSAID usage with the risk of developing cancer.

Biological & pharmaceutical bulletin, 2015
Use of nonsteroidal anti-inflammatory drugs (NSAIDs) is correlated with a reduced risk of cancer through the reduction of inflammation, which is an important risk factor. Several studies have investigated polymorphisms in the peroxisome proliferator-activated receptor gamma (PPARγ) gene and NSAID use in association with cancer risk.
Mai, Nagao, Youichi, Sato, Aiko, Yamauchi   +2 more
openaire   +1 more source

Peroxisome proliferator-activated receptor-γ polymorphism (rs1801282) is associated with obesity in Egyptian patients with coronary artery disease and type 2 diabetes mellitus

Journal of Genetic Engineering and Biotechnology, 2017
Peroxisome Proliferator-Activated Receptor-γ (PPAR-γ) gene is one of the possible genes linking diabetes mellitus (DM) with coronary artery disease (CAD). The aim of this study is to clarify whether PPAR-γ Pro12Ala polymorphism is associated with the development of CAD in type 2 diabetic patients and to evaluate PPAR-γ Pro12Ala polymorphism genetic ...
Nehal Salah Hasan, Solaf Ahmed Kamel, Mona Hamed, Eman Awadallah, Amany Hosny Abdel Rahman, Nevine Ibrahim Musa, Ghada Hussein Sayed Hussein   +6 more
openaire   +3 more sources

Polymorphism of the PPARG, AGTR1, VEGF-A genes: frequency and association with obesity phenotypes

Российский кардиологический журнал
Aim. To assess the association of the allele and genotype frequencies of following single nucleotide polymorphisms: rs1801282 of the peroxisome proliferator-activated receptor gamma (PPARG) gene, rs5186 of the angiotensin II receptor type 1 (AGTR1) gene,
A. E. Bragina, M. K. Vasilchenko, Yu. N. Rodionova, K. K. Osadchiy, A. P. Muravlev, M. A. Voronkov, E. A. Aleksandrova, V. I. Podzolkov   +7 more
doaj   +1 more source

Effects of the PPARG gene polymorphisms on markers of obesity and the metabolic syndrome in Bosnian subjects [PDF]

Journal of Medical Biochemistry, 2014
Background: Peroxisome proliferator-activated receptor gamma (PPARg) is a key transcription factor in adipogenesis, and also regulates a number of genes associated with lipid storage and insulin sensitivity.
Dujić Tanja, Bego Tamer, Mlinar Barbara, Semiz Sabina, Malenica Maja, Prnjavorac Besim, Ostanek Barbara, Marc Janja, Čaušević Adlija   +8 more
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Impact of Single Nucleotide Polymorphisms and of Clinical Risk Factors on New-Onset Diabetes Mellitus in HIV-Infected Individuals [PDF]

, 2017
Background.Metabolic complications, including cardiovascular events and diabetes mellitus (DM), are a major long-term concern in human immunodeficienc virus (HIV)-infected individuals.
Bernasconi, Enos, Cavassini, Matthias, Egger, Matthias, Elzi, Luigia, Furrer, Hansjakob, Gsponer, Thomas, Hirschel, Bernard, Ledergerber, Bruno, Martinez, Raquel, Rotger, Margalida, Taffé, Patrick, Tarr, Philip E., Telenti, Amalio, Vernazza, Pietro, Weber, Rainer   +14 more
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Consistency between cross-sectional and longitudinal SNP: blood lipid associations [PDF]

, 2018
Various studies have linked different genetic single nucleotide polymorphisms (SNPs) to different blood lipids (BL), but whether these "connections” were identified using cross-sectional or longitudinal (i.e., changes over time) designs has received ...
Beer-Borst, Sigrid, Costanza, Michael, Gaspoz, Jean-Michel, James, Richard, Morabia, Alfredo   +4 more
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