Results 91 to 100 of about 2,006 (194)

Interaction of genetic risk factors confers increased risk for metabolic syndrome: the role of peroxisome proliferator-activated receptor γ [PDF]

open access: yes, 2014
AIM: The aim of the study was to estimate the influence of interactions between peroxisome proliferator-activated receptor γ (PPARγ) and target genes lipoprotein lipase (LPL), interleukin 6 (IL6), angiotensin converting enzyme (ACE), and angiotensin ...
Božina, Tamara   +5 more
core   +1 more source

Combined influence of polymorphic variants of PPAR-2 (rs1801282) and ACE (rs4646994) genes on the onset of non-alcoholic fatty liver disease in patients with essential arterial hypertension and obesity

open access: yesJournal of Education, Health and Sport, 2018
Objective: to study a combined influence of polymorphic variants of PPAR-g2 (rs1801282) and ACE (rs4646994) genes on the onset of non-alcoholic fatty liver disease (NAFLD) in patients with essential arterial hypertension (EAH) and obesity. Materials and
Yu. M. Yarynych, L. P. Sydorchuk
doaj   +3 more sources

THE VALUE OF POLYMORPHISM RRO12ALA GENE PPARG IN VIOLATION OF LIPID PEROXIDATION AND ANTIOXIDANT PROTECTION IN PATIENTS WITH TYPE 2 DIABETES

open access: yesUkrainian Scientific Medical Youth Journal, 2016
Resume. The incidence of type 2 diabetes is increasing in Ukraine and worldwide. The severity of this disease is determined by the number of complications, which are based on lipid peroxidation (LPO).
V. Y. Mokrii   +2 more
doaj   +1 more source

Whole genome sequencing of an ethnic Pathan (Pakhtun) from the north-west of Pakistan. [PDF]

open access: yes, 2015
BACKGROUND: Pakistan covers a key geographic area in human history, being both part of the Indus River region that acted as one of the cradles of civilization and as a link between Western Eurasia and Eastern Asia. This region is inhabited by a number of
Bhak, Jong   +17 more
core   +1 more source

Pharmacogenetics of oral antidiabetic drugs [PDF]

open access: yes, 2013
Oral antidiabetic drugs (OADs) are used for more than a half-century in the treatment of type 2 diabetes. Only in the last five years, intensive research has been conducted in the pharmacogenetics of these drugs based mainly on the retrospective register
Becker, Matthijs L.   +2 more
core   +5 more sources

Lack of Genetic Associations of PPAR-γ and PGC-1α with Alzheimer's Disease and Parkinson's Disease with Dementia

open access: yesDementia and Geriatric Cognitive Disorders Extra, 2013
Background and Aims: Similar clinical and pathological features have been observed in Alzheimer's disease (AD) and Parkinson's disease with dementia (PDD).
Nobuto Shibata   +9 more
doaj   +1 more source

Polymorphisms associated with adalimumab and infliximab response in moderate-to-severe plaque psoriasis [PDF]

open access: yes, 2018
Aims. This study evaluated the influence of pharmacogenetics in psoriatic patients treated with adalimumab and/or infliximab. Materials & methods: Prospective observational study evaluating the association of 124 polymorphisms with the response to ...
Abad Santos, Francisco   +12 more
core   +1 more source

THE ASSOCIATION OF GENE POLYMORPHISMS WITH ATHLETE STATUS IN UKRAINIANS [PDF]

open access: yes, 2013
Athletic performance is a polygenic trait influenced by both environmental and genetic factors. Objective: to investigate individually and in combination the association of common gene polymorphisms with athlete status in Ukrainians.
Ildus I. Ahmetov   +3 more
core   +2 more sources

Вклад молекулярно-генетических маркеров в развитие синдрома поликистозных яичников [PDF]

open access: yes, 2015
ПОЛИКИСТОЗНОГО ЯИЧНИКА СИНДРОМ /генетПОЛИМОРФИЗМ ГЕНЕТИЧЕСКИЙГЕНЕТИЧЕСКИЕ ...
ружило, О. С.
core  

Obesity and diabetes genes are associated with being born small for gestational age: Results from the Auckland Birthweight Collaborative study [PDF]

open access: yes, 2010
Background Individuals born small for gestational age (SGA) are at increased risk of rapid postnatal weight gain, later obesity and diseases in adulthood such as type 2 diabetes, hypertension and cardiovascular diseases.
Angharad R Morgan   +6 more
core   +3 more sources

Home - About - Disclaimer - Privacy