G Allele of the rs1801282 Polymorphism in PPARγ Gene Confers an Increased Risk of Obesity and Hypercholesterolemia, While T Allele of the rs3856806 Polymorphism Displays a Protective Role Against Dyslipidemia: A Systematic Review and Meta-Analysis [PDF]
Frontiers in Endocrinology, 2022 BackgroundThe relationships between the rs1801282 and rs3856806 polymorphisms in nuclear receptor peroxisome proliferator-activated receptor gamma (PPARγ) gene and obesity indexes as well as serum lipid levels have been extensively investigated in ...
Chuan He, Song Yongyan
exaly +6 more sources
Relationship between PPAR‐γ gene polymorphisms and ischemic stroke risk: A meta‐analysis [PDF]
Brain and Behavior, 2021 Background Published researches have suggested some associations between PPAR‐γ and ischemic stroke (IS) development. This meta‐analysis was conducted to evaluate the association between PPAR‐γ gene polymorphisms and IS risk.
Lan Zhou, Gong-Li Yang
exaly +4 more sources
PPARG rs3856806 C>T Polymorphism Increased the Risk of Colorectal Cancer: A Case-Control Study in Eastern Chinese Han Population [PDF]
Frontiers in Oncology, 2019 Purpose: Functional variants in the peroxisome proliferator-activated receptor gamma (PPARG) and PPARG co-activator 1 (PPARGC1) family (e.g., PPARGC1A and PPARGC1B) genes were predicted to confer susceptibility to colorectal cancer (CRC).
Jing Lin +14 more
doaj +5 more sources
Association between PPARγ, PPARGC1A, and PPARGC1B genetic variants and susceptibility of gastric cancer in an Eastern Chinese population [PDF]
BMC Medical Genomics, 2022 Purpose Previous studies showed that peroxisome proliferator-activated receptor gamma (PPARγ) and PPARγ coactivator1 family (PPARGC1A and PPARGC1B) gene single nucleotide variants (SNVs)were strongly associated with cancer susceptibility.
Weifeng Tang +2 more
exaly +3 more sources
Biyokimya DergisiThe peroxisome proliferator-activated receptor gamma (PPARG) C161T polymorphism (rs3856806) may be a risk factor for in-stent restenosis (ISR) due to its known associations with type 2 diabetes (T2DM), obesity, and coronary artery disease (CAD).
Onur Kılıçarslan +2 more
exaly +3 more sources
Association between PPARG genetic polymorphisms and ischemic stroke risk in a northern Chinese Han population: a case-control study [PDF]
Neural Regeneration Research, 2019 Two common polymorphisms of the peroxisome proliferator-activated receptor gamma (PPARG) gene, rs1801282 and rs3856806, may be important candidate gene loci affecting the susceptibility to ischemic stroke.
Zhi-Yi He
exaly +4 more sources
GHMJ (Global Health Management Journal)Background: Diabetes Mellitus (DM) is a long-term metabolic illness brought on by either insufficient or inefficient insulin production by the pancreas. Worldwide, 537 million adults between the ages of 20 and 79 are thought to have DM.
Fauzaan Azhar Rizqulloh +2 more
exaly +4 more sources
Association of PPARG rs3856806 C>T polymorphism with body mass index, glycaemia and lipid parameters in Serbian adolescents [PDF]
Scripta Medica, 2021 Background/Aim: Peroxisome proliferator-activated receptor gamma (PPARg) belongs to a family of nuclear hormone receptors and ligand-activated transcription factors.
Vidović Vanja +4 more
doaj +2 more sources
Effects of PPARG and PPARGC1A gene polymorphisms on obesity markers [PDF]
Frontiers in Public Health, 2022 Pediatric obesity presents a multifactorial etiology, which involves genetic traits as well, including single nucleotide polymorphisms. The aim of the study is to investigate the contribution of PPARG gene polymorphisms (namely Pro12Ala rs1801282 ...
Carmen Muntean +3 more
doaj +2 more sources
PPARγ Gene Polymorphisms, Metabolic Disorders, and Coronary Artery Disease [PDF]
Frontiers in Cardiovascular Medicine, 2022 Being activated by endogenous and exogenous ligands, nuclear receptor peroxisome proliferator-activated receptor gamma (PPARγ) enhances insulin sensitivity, promotes adipocyte differentiation, stimulates adipogenesis, and has the properties of anti ...
Yongyan Song, Shujin Li, Chuan He
doaj +2 more sources