Results 1 to 10 of about 55,803 (164)
Peroxisome Proliferator-Activated Receptor Gamma Polymorphisms and Coronary Heart Disease
PPAR Research, 2009 Single nucleotide polymorphisms (SNPs) in the peroxisome proliferator-activated receptor γ (PPARG) gene have been associated with cardiovascular risk factors, particularly obesity and diabetes. We assessed the relationship between 4 PPARG SNPs (C-681G, C-
Jean Dallongeville +13 more
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The role of peroxisome proliferator-activated receptor gamma in prostate cancer
Asian Journal of Andrology, 2018 Despite great progress in the detection and treatment of prostate cancer, this disease remains an incredible health and economic burden. Although androgen receptor (AR) signaling plays a key role in the development and progression of prostate cancer ...
Catherine Elix +2 more
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Hepatic lipid homeostasis by peroxisome proliferator-activated receptor gamma 2
Liver Research, 2018 Peroxisome proliferator-activated receptor gamma (PPARγ or PPARG) is a ligand-activated transcription factor belonging to the nuclear hormone receptor superfamily. It plays a master role in the differentiation and proliferation of adipose tissues. It has
Yoon Kwang Lee +3 more
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Oleamide activates peroxisome proliferator-activated receptor gamma (PPARγ)
Lipids in Health and Disease, 2012 Background Oleamide (ODA) is a fatty acid primary amide first identified in the cerebrospinal fluid of sleep-deprived cats, which exerts effects on vascular and neuronal tissues, with a variety of molecular targets including cannabinoid receptors and gap
Dionisi Mauro +2 more
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Structural Biology Inspired Development of a Series of Human Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) Ligands: From Agonist to Antagonist [PDF]
International Journal of Molecular Sciences, 2023 Hiroyuki Miyachi
exaly +2 more sources
Oleuropein as an inhibitor of peroxisome proliferator-activated receptor gamma [PDF]
Genes & Nutrition, 2013 Oleuropein, the major phenolic compound found in olive leaves and oil, exerts antioxidant, anti-inflammatory and anti-atherogenic effects and suppresses the adipocyte differentiation in vitro. Herein, we characterized molecular mechanisms underlying the anti-adipogenic effects of oleuropein on 3T3-L1 cells and adipocytes derived from stromal-vascular ...
Svobodova, M. +4 more
openaire +3 more sources
PPARG (peroxisome proliferator-activated receptor gamma) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011 Review on PPARG (peroxisome proliferator-activated receptor gamma), with data on DNA, on the protein encoded, and where the gene is implicated.
Astarci, E, Banerjee, S
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Peroxisome proliferator-activated receptor gamma and BRCA1 [PDF]
Endocrine-Related Cancer, 2019 Peroxisome proliferator-activated receptor gamma agonists have been proposed as breast cancer preventives. Individuals who carry a mutated copy of BRCA1, DNA repair-associated gene, are at increased risk for development of breast cancer. Published data in the field suggest there could be interactions between peroxisome proliferator-activated receptor ...
openaire +2 more sources
Klotho, Oxidative Stress, and Mitochondrial Damage in Kidney Disease
Antioxidants, 2023 Reducing oxidative stress stands at the center of a prevention and control strategy for mitigating cellular senescence and aging. Kidney disease is characterized by a premature aging syndrome, and to find a modulator targeting against oxidative stress ...
Javier Donate-Correa +4 more
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Türk Biyokimya Dergisi, 2021 Peroxisome proliferator activated receptor gamma (PPARγ) agonists used for the treatment of Diabetes Mellitus (DM), has important roles on the regulation of metabolism including ketogenesis in fasting and low glucose states.
Pınarbaşı Arzu +4 more
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