Results 11 to 20 of about 257 (91)

PPARG Polymorphisms Are Associated with Unexplained Mild Vision Loss in Patients with Type 2 Diabetes Mellitus [PDF]

Journal of Ophthalmology, 2019
Objectives. To investigate whether the presence of peroxisome proliferator-activated receptor gamma (PPARG) gene polymorphisms is associated with unexplained mild visual impairment (UMVI) in patients with type 2 diabetes mellitus (T2DM). Methods. A total
Tao Li, Xian Xu, Yi Xu, Peiyao Jin, Jianhua Chen, Yongyong Shi, Haidong Zou   +6 more
doaj   +3 more sources

Uncoupling Protein 2 and Peroxisome Proliferator-Activated Receptor γ Gene Polymorphisms in Association with Diabetes Susceptibility in Chinese Han Population with Variant Glucose Tolerance [PDF]

International Journal of Endocrinology, 2018
Objective. To investigate the association of polymorphisms in uncoupling protein 2 (UCP2) and peroxisome proliferator-activated receptor (PPARγ) with glucolipid metabolism in Chinese Han population. Methods. Five hundred eighty-nine subjects were divided
Meicen Zhou, Shuli He, Fan Ping, Wei Li, Lixin Zhu, Xiangli Cui, Linbo Feng, Xuefeng Zhao, Huabing Zhang, Yuxiu Li, Qi Sun   +10 more
doaj   +3 more sources

Peroxisome proliferator-activated receptor α and γ gene polymorphisms among South Indian patients with diabetic dyslipidaemia [PDF]

Indian Journal of Endocrinology and Metabolism, 2023
Background: Peroxisome proliferator-activated receptors (PPAR) α and γ genes play an important role in dyslipidaemia of T2DM. Aims: To estimate the frequency distribution of PPAR α and γ gene polymorphisms in South Indian T2DM patients with dyslipidaemia
Isaac J Bage, Sadishkumar Kamalanathan, Sandhiya Selvarajan, Jayaprakash Sahoo, Jayanthi Mathaiyan, Dukhabandhu Naik   +5 more
doaj   +2 more sources

Impact of Proliferator-Activated Receptor γ Gene Polymorphisms on Risk of Schizophrenia: A Case-Control Study and Computational Analyses [PDF]

Iranian Journal of Psychiatry, 2020
Objective: Schizophrenia (SCZ) is a common psychiatric disorder characterized by a complex mode of inheritance. Peroxisome proliferator-activated receptor-γ (PPARG) mainly regulates lipid and glucose metabolisms while it is constitutively expressed in ...
Saman Sargazi, Fariba Mirani Sargazi, Mahdiyeh Moudi, Milad Heidari Nia, Ramin Saravani, Shekoufeh Mirinejad, Sheida Shahraki, Mansoor Shakiba   +7 more
doaj   +2 more sources

Peroxisome proliferator-activated receptor gamma gene variants modify human airway and systemic responses to indoor dibutyl phthalate exposure [PDF]

Respiratory Research, 2022
Background Single nucleotide polymorphisms (SNPs) of peroxisome proliferator-activated receptor gamma (PPAR-γ; gene: PPARG) and oxidative stress genes are associated with asthma risk. However, whether such variants modulate responses to dibutyl phthalate
Clarus Leung, Min Hyung Ryu, Anette Kocbach Bølling, Danay Maestre-Batlle, Christopher F. Rider, Anke Hüls, Oscar Urtatiz, Julie L. MacIsaac, Kevin Soon-Keen Lau, David Tse Shen Lin, Michael S. Kobor, Chris Carlsten   +11 more
doaj   +2 more sources

Effects of FTO and PPARγ variants on intrauterine growth restriction in a Brazilian birth cohort [PDF]

Brazilian Journal of Medical and Biological Research, 2021
Intrauterine growth restriction (IUGR) is related to a higher risk of neonatal mortality, minor cognitive deficit, metabolic syndrome, and cardiovascular disease in adulthood.
M.R. Barbieri, A.M. Fontes, M.A. Barbieri, M.C.P. Saraiva, V.M.F. Simões, A.A.M. da Silva, K.J. Abraham, H. Bettiol   +7 more
doaj   +2 more sources

Associations among perfluorooctanesulfonic/perfluorooctanoic acid levels, nuclear receptor gene polymorphisms, and lipid levels in pregnant women in the Hokkaido study [PDF]

Scientific Reports, 2021
The effect of interactions between perfluorooctanesulfonic (PFOS)/perfluorooctanoic acid (PFOA) levels and nuclear receptor genotypes on fatty acid (FA) levels, including those of triglycerides, is not clear understood.
Sumitaka Kobayashi, Fumihiro Sata, Houman Goudarzi, Atsuko Araki, Chihiro Miyashita, Seiko Sasaki, Emiko Okada, Yusuke Iwasaki, Tamie Nakajima, Reiko Kishi   +9 more
doaj   +2 more sources

Rare Mutations of Peroxisome Proliferator-Activated Receptor Gamma: Frequencies and Relationship with Insulin Resistance and Diabetes Risk in the Mixed Ancestry Population from South Africa

International Journal of Endocrinology, 2014
Background. Genetic variants in the nuclear transcription receptor, PPARG, are associated with cardiometabolic traits, but reports remain conflicting.
Z. Vergotine, A. P. Kengne, R. T. Erasmus, Y. Y. Yako, T. E. Matsha   +4 more
doaj   +2 more sources

Analyses of association between PPAR gamma and EPHX1 polymorphisms and susceptibility to COPD in a Hungarian cohort, a case-control study

BMC Medical Genetics, 2010
Background In addition to smoking, genetic predisposition is believed to play a major role in the pathogenesis of chronic obstructive pulmonary disease (COPD).
László Nagy, András Penyige, Beata Scholtz   +2 more
exaly   +3 more sources

Genetic Background of Hypertension in Connective Tissue Diseases. [PDF]

J Immunol Res, 2020
Peroxisome proliferator‐activated receptors (PPAR gamma-2) and beta‐3‐adrenergic receptors (ADRB3) are involved in the risk of hypertension. But their exact role in blood pressure modulation in patients with connective tissue diseases (CTD) is still not well defined.
Grygiel-Górniak B, Ziółkowska-Suchanek I, Kaczmarek E, Puszczewicz M, Rozwadowska N.   +4 more
europepmc   +2 more sources