Results 161 to 170 of about 28,617 (282)

S‐Adenosylmethionine (SAM) hydrolases counter increased SAM epimerisation in thermophilic archaea

The FEBS Journal, EarlyView.
S‐Adenosyl‐l‐methionine (SAM) is a vital enzyme cofactor. Epimerisation at the sulfonium centre of biologically active (SS,SCα)‐SAM is driven by heat, yielding biologically inactive (RS,SCα)‐SAM. Here, two novel archaeal SAM hydrolases from the thermophilic Sulfolobus acidocaldarius and the halophilic Haloferax volcanii are shown to cleave (RS,SCα)‐SAM.
Agnes Bartels, Michael K. F. Mohr, Phillip Nußbaum, Marie Joest, Bianca Wassmer, Laurent Rasquin, Sonja‐Verena Albers, Jennifer N. Andexer   +7 more
wiley   +1 more source

Evaluating Treatment Dynamics in Refractory Status Epilepticus: A Retrospective Observational Cohort Study. [PDF]

Neurohospitalist
Barra M, Vaitkevicius H, Farrokh S, Saikumar S, Shah S, Katariya D, Rybak E.   +6 more
europepmc   +1 more source

Length‐Based Spawning Potential Ratio Assessment of Key Species From a Remote Recreational Fishery at Diego Garcia, Indian Ocean

Fisheries Management and Ecology, EarlyView.
ABSTRACT Recreational fisheries in remote regions often operate under limited regulation and data availability, presenting challenges for sustainable management. Diego Garcia, located within the Chagos Marine Protected Area, hosts a unique recreational reef fishery embedded within a highly protected environment. We assessed the stock status of five key
Andrea N. Odell, David J. Curnick, Ronan C. Roche, Claire Collins, Kathryn E. Dawson, Ka'ohinani Kawahigashi, Chloe Le Blond, Andrew McInnis, Anna Patel, Sivajyodee Sannassy Pilly, Isobel Strudwick, Ami Vice, Brett M. Taylor   +12 more
wiley   +1 more source

"A Change in Culture From It Being an Optional Extra to an Integral Part of Education"-Teacher's Experiences of Teaching Relationships and Sexuality Education (RSE) to Learners With Severe/Profound Intellectual Disabilities in the Republic of Ireland. [PDF]

J Appl Res Intellect Disabil
Connolly L, O'Mahony K, Scully C.
europepmc   +1 more source

Dolutegravir population pharmacokinetics in racially, sex‐ and age‐diverse and antiretroviral therapy‐experienced adults with HIV in the United States

HIV Medicine, EarlyView.
Abstract Objectives Dolutegravir (DTG) has been associated with weight gain in women with HIV, Black people with HIV and people with HIV60 years. This study aimed to characterise DTG population pharmacokinetics (PopPK) in a diverse population including these sub‐populations.
Adrian Khoei, Andrew Edmonds, Yen Chang, Catalina Ramirez, Mackenzie Vogan, Amanda Poliseno, Steven Wolinsky, Ken Ho, Todd T. Brown, Joseph B. Margolick, Jacquett Batson, Jennifer Hoffmann, Mark A. Marzinke, Mirjam‐Colette Kempf, Maria L. Alcaide, Joffi Effoe, Cecile D. Lahiri, Igho Ofotokun, Anandi N. Sheth, Stephen Gange, Audrey L. French, Bani Tamraz, Bradley E. Aouizerat, Phyllis C. Tien, Seble G. Kassaye, Jack DeHovitz, Kathryn Anastos, Kara W. Chew, Michelle Floris‐Moore, Julie B. Dumond   +29 more
wiley   +1 more source

When one race is not enough: A relay model explains multisensory response times. [PDF]

PLoS Comput Biol
Roberts K, Otto TU.
europepmc   +1 more source

The Silent Strain: The Psychological Toll of Multiracial Microaggressions

Journal of Applied Social Psychology, EarlyView.
ABSTRACT In the United States, the Multiracial population is the fastest‐growing racial identity, with projections suggesting that one in five people will be Multiracial by 2050. While research has begun to investigate the microaggressions that Multiracial Americans experience, less work has examined their potential psychological consequences.
Cheryl L. Dickter, Elyssa Kancherla, Hannah Y. Khan   +2 more
wiley   +1 more source

The research software engineering (RSE) survey dataset (2016-2022): A longitudinal and international resource for studying the research software workforce. [PDF]

Data Brief
Kijewska W, Packer HS, Hettrick S.
europepmc   +1 more source

How Hybrid Work Shapes Communication Ties: The Role of Concern about Relationship Loss and Organizational Identification

Journal of Management Studies, EarlyView.
Abstract The rapid shift to hybrid work settings has raised concerns about decreased workplace interactions and communication ties. Based on Need‐to‐Belong Theory, this study extends previous research by adopting the concept of ‘concern about relationship loss’ to explore when and how hybrid work leads to the retention of work‐related communication ...
Christian Tröster, Prisca Brosi
wiley   +1 more source

Anesthetics in status epilepticus: does one size fits it all?-A scoping review on titration goals, timing, and patient selection. [PDF]

Front Neurol
Fisch U, De Stefano P, Baumann SM, Rüegg S, Sutter R.   +4 more
europepmc   +1 more source