Results 181 to 190 of about 37,268 (291)

Distinct Tissue Localization and Transcriptional Profiles of Shiga Toxin-Producing <i>Escherichia coli</i> With and Without the Locus of Enterocyte Effacement at the Bovine Recto-Anal Junction. [PDF]

Int J Microbiol
Méndez D, Cartajena JT, Flores J, Quintanilla F, Toledo J, Cruz P, Dorner J, Escobar B, Ríos MP, Lavanderos C, Ferrer V, Rojas P, Luna D, Lapierre L, Kudva IT, Martínez V, Galarce N.   +16 more
europepmc   +1 more source

VEGF inhibitor‐induced vascular dysfunction involves redox‐sensitive PARP activation and SIRT1 disruption

Experimental Physiology, EarlyView.
Abstract Vascular endothelial growth factor receptor (VEGFR) inhibitors are effective antiangiogenic agents used in cancer therapy. However, they are associated with cardiovascular disease, including hypertension and vascular dysfunction. The molecular mechanisms underlying these cardiovascular toxicities are unclear, but oxidative stress might be ...
Karla B. Neves, Rheure Alves‐Lopes, Augusto C. Montezano, Rhian M. Touyz   +3 more
wiley   +1 more source

Neuromuscular fatigability with repeated exercise in hypoxia: From single‐joint paradigms to sprints

The Journal of Physiology, EarlyView.
Abstract figure legend Acute hypobaric or normobaric hypoxic exposure accelerates neuromuscular fatigability during repeated exercise. Indices of peripheral and central fatigue are not different at exhaustion in mild, moderate and severe hypoxia compared with normoxia, but task failure occurs earlier.
Luca Ruggiero, Franck Brocherie, Olivier Girard, Nathan Townsend, Chris J. McNeil, Grégoire P. Millet   +5 more
wiley   +1 more source

Integrating mechanical, physiological, and muscle oxygenation responses during field-based tethered repeated-sprint exercise in male professional soccer players. [PDF]

Physiol Rep
Manchado-Gobatto FB, Torres RS, Rasteiro FM, Pinto A, Scariot PPM, Marostegan AB, Cruz JP, Orsi JB, de Araujo LS, Gobatto CA.   +9 more
europepmc   +1 more source

Model‐Based Analysis with Mechanistic Insights to CAR‐T‐Cell Therapy Kinetics: Case Study with Axicabtagene Ciloleucel and Brexucabtagene Autoleucel

Clinical Pharmacology &Therapeutics, Volume 120, Issue 4, Page 1027-1040, October 2026.
Model‐informed drug development is increasingly used to support chimeric antigen receptor (CAR)‐T‐cell therapy programs. However, most population pharmacokinetic (PK) CAR‐T‐cell models available in literature are variations of an empirical piecewise‐linear model, which accurately describes the observed data but lacks a mechanistic foundation.
Anna M. Mc Laughlin, Martin Bergstrand, Ana Ruiz‐Garcia, Simone Filosto, Rhine Shen   +4 more
wiley   +1 more source

"A Change in Culture From It Being an Optional Extra to an Integral Part of Education"-Teacher's Experiences of Teaching Relationships and Sexuality Education (RSE) to Learners With Severe/Profound Intellectual Disabilities in the Republic of Ireland. [PDF]

J Appl Res Intellect Disabil
Connolly L, O'Mahony K, Scully C.
europepmc   +1 more source

Self‐Esteem and Repetitive Negative Thinking as Mediators of the Association Between Bullying and Disordered Eating

Journal of Clinical Psychology, Volume 82, Issue 10, Page 1617-1627, October 2026.
ABSTRACT Objective Eating disorders are associated with marked distress and impairment, including elevated risk for anxiety, depression, and suicidality. Bullying victimization is associated with eating disorder symptoms in late adolescence and young adulthood, when peer relationships and social evaluation are developmentally salient.
Kaitlynn E. Ellis, Camille Archer, Gabrielle E. Reimann, Yulan D. Chen, Ralph E. Francois, Antonia N. Kaczkurkin   +5 more
wiley   +1 more source

Evaluating Treatment Dynamics in Refractory Status Epilepticus: A Retrospective Observational Cohort Study. [PDF]

Neurohospitalist
Barra M, Vaitkevicius H, Farrokh S, Saikumar S, Shah S, Katariya D, Rybak E.   +6 more
europepmc   +1 more source

Diffusion MRI of the Body: Beyond PGSE‐EPI

Journal of Magnetic Resonance Imaging, Volume 64, Issue 4, Page 881-897, October 2026.
ABSTRACT Diffusion magnetic resonance imaging (dMRI) is a widely used clinical imaging technique which is sensitive to changes in tissue microstructure including cellularity, perfusion, and tissue damage. DMRI has been used in whole‐body imaging as well as in targeted imaging of every major anatomical region.
Matthew T. Cherukara, Wenbo Sun, David Leitão, Shaihan Malik, Radhouene Neji, Joseph V. Hajnal, Andrada Ianus   +6 more
wiley   +1 more source

When one race is not enough: A relay model explains multisensory response times. [PDF]

PLoS Comput Biol
Roberts K, Otto TU.
europepmc   +1 more source