Results 201 to 210 of about 37,268 (291)

Optimal dosing for vascular anomalies paediatric patients with population pharmacokinetic model of sirolimus

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 9, Page 3115-3123, September 2026.
Abstract Aim Sirolimus is currently used off‐label for paediatric patients with vascular anomalies. However, the optimal dosage regimen for paediatric patients remains controversial. This study aimed to determine the optimal dosing regimen of sirolimus in these patients using a population pharmacokinetic (PK) model.
Seongmee Jeong   +13 more
wiley   +1 more source

Pregnancy‐related effect on elexacaftor, tezacaftor and ivacaftor pharmacokinetics in women with cystic fibrosis

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 9, Page 3202-3213, September 2026.
Aim The number of pregnancies among women with cystic fibrosis (wwCF) has steadily increased over the past decade. However, the pharmacokinetics (PK) of elexacaftor–tezacaftor–ivacaftor (ETI) during gestation remains uncharacterized, despite its widespread use in this population.
Paulette Magnas   +16 more
wiley   +1 more source

Oseltamivir drug‐disease modelling in infants with influenza virus infection

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 9, Page 3214-3222, September 2026.
Abstract Aims Oseltamivir is a commonly used neuraminidase inhibitor for treatment of influenza infection, but little data exist regarding concentration‐response relationships. Methods Pharmacokinetic (PK) and viral dynamic data from an earlier NIAID Collaborative Antiviral Study Group trial in paediatric patients with influenza from 0–23 months of age
Kun Wang   +4 more
wiley   +1 more source

Psychological Profile of Bariatric Surgery Candidates: A Cross‐Sectional Study

open access: yesBrain and Behavior, Volume 16, Issue 9, September 2026.
The present study examined the psychological profile of bariatric surgery candidates, revealing that early childhood trauma, parental neglect, and coping strategies were associated with adult psychopathology. No direct relationship was identified between BMI and psychological findings, underscoring the necessity of mandatory psychiatric screening ...
Şafak Yalçin Şahiner   +3 more
wiley   +1 more source

Empowering the Self of Teachers: Effects of a Person‐Centred Experiential Intervention on Self‐Esteem, Self‐Efficacy and Self‐Acceptance

open access: yesCounselling and Psychotherapy Research, Volume 26, Issue 3, September 2026.
ABSTRACT Aim The current study examined the effects of the person‐centred intervention ‘Listen to Me, Teacher’ on primary school teachers' self‐esteem, self‐efficacy and self‐acceptance in Greece. Grounded in Carl Rogers’ theoretical framework, the intervention aimed to enhance self‐esteem, self‐efficacy and self‐acceptance—dimensions associated with ...
D. Dimitrakopoulou   +2 more
wiley   +1 more source

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