Results 221 to 230 of about 193,591 (315)

Population Pharmacokinetic Modeling and Exposure‐Response Analyses of Nemtabrutinib in Patients With Hematologic Malignancies

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 5, May 2026.
ABSTRACT Nemtabrutinib is a Bruton's tyrosine kinase (BTK) inhibitor under clinical investigation in patients with hematologic malignancies, including chronic lymphocytic leukemia and small lymphocytic lymphoma (CLL/SLL). Nemtabrutinib plasma concentration data from 578 patients enrolled in phase 1 and 2 clinical studies, treated with doses from 5 to ...
Chiara C. Kemal, Thijs J. Zweers, Elke H. J. Krekels, Manash S. Chatterjee   +3 more
wiley   +1 more source

Revealing Hidden Length by Force: Decoupling Modulus and Toughness in Network Gels. [PDF]

ACS Cent Sci
Thazhathethil S, Hu X.
europepmc   +1 more source

L'appropriation de la RSE par les dirigeants de PME. Le réseau comme vecteur de l'apprentissage managérial

, 2009
Élise Bonneveux, Jean-Yves Saulquin
semanticscholar   +1 more source

MicroRNA 15a and 16 Regulate Proteostasis in Non‐Small Cell Lung Cancer

FASEB BioAdvances, Volume 8, Issue 5, May 2026.
Overexpression of microRNA15a/16 slows rates of tumor growth and protein synthesis in cultured lung cancer cells. These co‐transcribed miRNAs target a wide array of anabolic and pro‐tumor processes, indicating their central role in regulating lung cancer cellular anabolism. ABSTRACT Aberrant anabolic activity is critical to tumor biology; however, much
Patrick J. Ryan, Bethany C. Guerra, Peter Nghiem, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +5 more
wiley   +1 more source

Between Vulnerability and Connection: Longitudinal Evidence on the Impact of Transformative Religious/Spiritual Experiences. [PDF]

Stress Health
Chen ZJ, Wilkinson R, Cowden RG.
europepmc   +1 more source

Electrocardiographic Predictors of Major Adverse Cardiovascular Events in Women With Suspected Ischemia and no Obstructive Coronary Artery Disease: Results of the Women's Ischemia Syndrome Evaluation

Annals of Noninvasive Electrocardiology, Volume 31, Issue 3, May 2026.
A cohort of 481 female participants of the Women's Ischemia Syndrome Evaluation (WISE) Original study clinically phenotyped as having suspect ischemia with no obstructive coronary arteries (INOCA) were evaluated for baseline ECG and clinical predictors of time to incident major adverse cardiac events (MACE).
Jennifer R. Dungan, Yasmeen K. Taha, Qinglin Pei, Michael T. Weaver, Michael J. Tavormina, Steven E. Reis, Eileen M. Handberg, C. Noel Bairey Merz, Carl J. Pepine   +8 more
wiley   +1 more source

Micropropagation and ex vitro acclimatization of Lonicera caerulea var. altaica: molecular identification and protocol optimization. [PDF]

Sci Rep
Zhanybekova Z, Bayanbay S, Danilova A, Imanbayeva A, Kakimzhanova А.   +4 more
europepmc   +1 more source

A model‐based analysis of the CYP2C9 genotype effects on fluconazole inhibition using flurbiprofen, ketoprofen and tolbutamide as probe drugs

British Journal of Pharmacology, Volume 183, Issue 10, Page 2482-2496, May 2026.
Background The activity of CYP2C9, an important drug metabolism enzyme, is subject to the impact of genetic polymorphism. The single nucleotide polymorphism *3 is significantly associated with the increased exposure of CYP2C9 substrates. In addition, metabolic enzyme inhibitors such as fluconazole may also increase the drug exposure of CYP2C9 ...
Shen Cheng, Darcy R. Flora, Mutaz M. Jaber, Allan E. Rettie, Richard C. Brundage, Timothy S. Tracy   +5 more
wiley   +1 more source

Status Epilepsy Syndromes Made Easy: Pediatric Perspectives. [PDF]

Children (Basel)
Hon KLE, Leung AKC, Leung KKY, Torres AR.   +3 more
europepmc   +1 more source

Clearance of mannitol for assessment of glomerular filtration rate in chronic kidney disease: A validation against iohexol clearance

Clinical Physiology and Functional Imaging, Volume 46, Issue 3, May 2026.
Abstract This study evaluates mannitol as a clearance marker for measuring glomerular filtration rate (GFR) in outpatients with chronic kidney disease (CKD). Multi‐sample iohexol clearance served as the reference method. Twenty patients with CKD, stages 3–4, received bolus injections of both clearance markers simultaneously.
Katalin Kiss, Aso Saeed, Sven‐Erik Ricksten, Gudrun Bragadottir   +3 more
wiley   +1 more source