Results 191 to 200 of about 28,617 (282)

In vitro immunotoxicity of important mycotoxins detected in commercial dry dog and cat food in relation to internal exposure. [PDF]

Mycotoxin Res
Dänicke S, Kersten S, Saltzmann J, Mickenautsch N, Sulyok M, Schatzmayr D, Doupovec B, Paßlack N.   +7 more
europepmc   +1 more source

A dose‐finding population pharmacokinetic/pharmacodynamic model of ginisortamab, an anti‐gremlin‐1 monoclonal antibody, in patients with solid tumours

British Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2885-2898, August 2026.
Aims Ginisortamab, a first‐in‐class human monoclonal antibody for the treatment of advanced solid tumours, binds to gremlin‐1 and restores bone morphogenetic protein signalling. We used pharmacokinetic/pharmacodynamic (PK/PD) modelling to characterize the relationship between ginisortamab dose and serum gremlin‐1 binding, using model‐based simulations ...
Yin Cheong Wong, Luisa Rojas Chavarro, Paul Jones, David Egging, Wanchana Ungphakorn, Marta Valle, Ivan Matthews   +6 more
wiley   +1 more source

GPA33 forms a distinct diagnostic target class to Claudin 18.2 in oesophageal adenocarcinoma enabling the development of a novel GPA33 antibody-based detection platform. [PDF]

Cell Mol Biol Lett
Brydon J, Krejcir R, Zavadil-Kokas F, Singh A, Henek T, Hernychova L, Coleman S, Al Shboul S, Hrabal V, Kuncova Z, Mayordomo MY, Arcimowicz Ł, Ball KL, Padariya M, Kalathiya U, Vojtesek B, Hupp T, O'Neill JR.   +17 more
europepmc   +1 more source

Assessment of Pulmonary Vascular Impedance in Patients With Severe Pulmonary Arterial Hypertension

Comprehensive Physiology, Volume 16, Issue 4, August 2026.
Pulmonary vascular impedance (PVZ) was calculated from clinical PA pressure and RVOT flow velocity profiles. Participants with increased pulmonary vascular resistance have increased PVZ, afterload, and diastolic stiffness. The characteristic impedance (ZC) to mean PA pressure relationship models the effect of proximal vasculature remodeling on ZC for a
Keeley Shea Ravellette, Saad Kubba, Frank Servin, Michael Insel, Joe G. N. Garcia, Tushar Acharya, Franz P. Rischard, Rebecca R. Vanderpool   +7 more
wiley   +1 more source

Surgical resection as salvage therapy for super-refractory status epilepticus: a report of two cases. [PDF]

Epilepsy Behav Rep
Ding J, Zhao C, Cui D, Du W, Jiao H.
europepmc   +1 more source

Cottonseed Cake as an Additive in BRS Capiaçu Grass Silage: Impacts on the Fermentative, Chemical, and Digestibility Characteristics of the Silages

New Zealand Journal of Agricultural Research, Volume 69, Issue 4, August 2026.
One of the major challenges in livestock production in the semiarid region of Brazil is the scarcity of water and feed for animals. In this context, the valorization of adapted forage crops associated with by‐products generated in the agro‐industry can contribute to circular agriculture, reduce waste, and promote more efficient use of natural resources,
Lucas Rodrigues Caires, Caio Martins Marques, Ignacio Aspiazu, Vicente Ribeiro Rocha Júnior, Alexandre Soares dos Santos, André Santos de Souza, Tiago Alves Corrêa Carvalho da Silva, João Paulo Sampaio Rigueira, Hugo Tiago Ribeiro Amaro, Cinara da Cunha Siqueira Carvalho, Flávio Pinto Monção   +10 more
wiley   +1 more source

RSE-Ops

, 2021
openaire   +2 more sources

Population Pharmacokinetic and Exposure‐Response Analysis of Vancomycin Nephrotoxicity in Cystic Fibrosis Patients

Pediatric Pulmonology, Volume 61, Issue 8, August 2026.
ABSTRACT Introduction Acute pulmonary exacerbations (APE) in persons with cystic fibrosis (PwCF) are associated with a reduction in long‐term pulmonary function. Vancomycin is recommended as first‐line treatment of methicillin‐resistant Staphylococcus aureus ‐APE in PwCF.
Jessica Barry, J. G. C. van Hasselt, Michael Evans, Elizabeth B. Hirsch, Jordan Dunitz, Sarah Shockley, Joanne Billings, Sílvia M. Illamola   +7 more
wiley   +1 more source

Effects of Kangaroo care during retinopathy screening examination: a randomised clinical trial. [PDF]

BMJ Paediatr Open
Huang HB, Xue Y, Liang Y, Wan XQ, Wu J, Zhang QS, Cheung PY.   +6 more
europepmc   +1 more source

Application of Population‐Based Meta‐Heuristic Algorithms for Robust Initialization in Mechanistic Pharmacometric Modeling

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 8, August 2026.
ABSTRACT Mechanistic PK/PD models represent complex biological systems in which model parameters are in nonlinear, multidimensional parameter spaces and often require robust optimization informed by experimental data, making parameter estimation a critical yet challenging aspect of pharmacometric analysis.
Dongjin Lee, Chih‐Wei Lin
wiley   +1 more source