Results 161 to 170 of about 152,172 (364)

Safety and Immunogenicity of the Respiratory Syncytial Virus Vaccine RSV/ΔNS2/Δ1313/I1314L in RSV-Seronegative Children

open access: yesJournal of Infectious Diseases, 2019
Background Respiratory syncytial virus (RSV) is the leading global cause of severe pediatric acute respiratory tract illness, and a vaccine is needed. RSV/ΔNS2/Δ1313/I1314L contains 2 attenuating elements: (1) deletion of the interferon antagonist NS2 ...
R. Karron   +5 more
semanticscholar   +1 more source

Antenatal Corticosteroid Administration and Childhood Respiratory Morbidity: A Regression Discontinuity Study

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To determine if routine administration of antenatal corticosteroids affects the risk of infant lower respiratory tract infection and/or childhood asthma. Design Linked population‐based cohort analysed using a regression discontinuity design, which better controls for confounding than standard observational studies.
Jennifer A. Hutcheon   +8 more
wiley   +1 more source

Genetic delivery of an anti-RSV antibody to protect against pulmonary infection with RSV

open access: yesVirology, 2008
Respiratory syncytial virus (RSV) is a common cause of severe lower respiratory tract infections. Protection against infection with RSV can be achieved by monthly administration of the humanized monoclonal antibody palivizumab. The present study analyzes if genetic delivery of a murine version of palivizumab by single administration would achieve high ...
Ju Joh   +6 more
openaire   +3 more sources

The 15‐Year Survival Advantage: Immune Resilience as a Salutogenic Force in Healthy Aging

open access: yesAging Cell, EarlyView.
Human aging shows puzzling diversity: similar aging rates yet vastly different health outcomes. Our study of ~17,500 people revealed a health‐promoting trait (more common in women) linked to strong immune resilience and high expression of TCF7, a key immune gene. This trait enables individuals to fight infections like COVID‐19 more effectively, respond
Muthu Saravanan Manoharan   +176 more
wiley   +1 more source

Five Years’ Experience with Respiratory Syncytial Virus Among Hospitalized Patients: A Retrospective Study from Jazan, Saudi Arabia

open access: yesInfection and Drug Resistance
Nabil S Dhayhi,1,* Ali Aqeel,2,* Salman Ghazwani,3 Ibrahim M Gosadi,4 Haleemah Mohammed AlQassimi,5 Abdullah Thubab,6 Ibrahim Abdullah Sairam,6 Majed Ahmed Hakami,6 Fahd Ahmed Sawan,6 Sabreen Mohammed Asiry,7 Mawahib Khalifa,7 Hadi Daghreeri,8 ...
Dhayhi NS   +17 more
doaj  

Age‐Related Oxidative Stress and Mitochondrial Dysfunction in Lymph Node Stromal Cells Limit the Peripheral T Cell Homeostatic Maintenance and Function

open access: yesAging Cell, EarlyView.
Aging of the lymph node stromal cells limits their ability to support the survival and maintenance of peripheral naive T cells. The lymph node stromal cells are critical for providing the survival and trophic signals to peripheral naïve T cells, and after the early‐life thymic involution, these secondary lymphoid organ stromal microniches are decisive ...
Sandip Ashok Sonar   +6 more
wiley   +1 more source

CELL MEDIATED IMMUNITY CONFERRED BY NATURAL RSV INFECTION AND KILLED VACCINE [PDF]

open access: bronze, 1974
Hyun W Kim   +4 more
openalex   +1 more source

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