Results 51 to 60 of about 161,851 (302)

Development of an in vitro periodontal biofilm model for assessing antimicrobial and host modulatory effects of bioactive molecules [PDF]

open access: yes, 2014
Background: Inflammation within the oral cavity occurs due to dysregulation between microbial biofilms and the host response. Understanding how different oral hygiene products influence inflammatory properties is important for the development of new ...
AK Joe   +44 more
core   +1 more source

The Global Epidemiology of RSV in Community and Hospitalized Care: Findings From 15 Countries

open access: yesOpen Forum Infectious Diseases, 2021
Background Respiratory syncytial virus (RSV) is one of the leading causes of acute respiratory tract infections. To optimize control strategies, a better understanding of the global epidemiology of RSV is critical.
Lisa Staadegaard   +33 more
semanticscholar   +1 more source

Roadblocks to translational challenges on viral pathogenesis. [PDF]

open access: yes, 2013
Distinct roadblocks prevent translating basic findings in viral pathogenesis into therapies and implementing potential solutions in the clinic. An ongoing partnership between the Volkswagen Foundation and Nature Medicine resulted in an interactive ...
Deeks, Steven   +4 more
core   +1 more source

The recent landscape of RSV vaccine research

open access: yesTherapeutic Advances in Vaccines and Immunotherapy
Respiratory syncytial virus (RSV) causes a significant burden of acute respiratory illness across all ages, particularly for infants and older adults. Infants, especially those born prematurely or with underlying health conditions, face a high risk of ...
Karen Kelleher   +2 more
semanticscholar   +1 more source

Effectiveness of long-acting monoclonal antibodies against laboratory-confirmed RSV in children aged < 24 months and hospitalised for severe acute respiratory infection, European pilot study, 2024 to 2025

open access: yesEurosurveillance
We measured effectiveness of nirsevimab against laboratory-confirmed respiratory syncytial virus (RSV) infection in a test-negative case-control study among children aged 
VEBIS hospital network RSV IE group
doaj   +1 more source

Epidemic dynamics of respiratory syncytial virus in current and future climates. [PDF]

open access: yes, 2019
A key question for infectious disease dynamics is the impact of the climate on future burden. Here, we evaluate the climate drivers of respiratory syncytial virus (RSV), an important determinant of disease in young children.
Baker, Rachel E   +8 more
core   +2 more sources

The respiratory syncytial virus nucleoprotein–RNA complex forms a left-handed helical nucleocapsid [PDF]

open access: yes, 2013
Respiratory Syncytial Virus (RSV) is an important human pathogen. Its nucleocapsid (NC), which comprises the negative sense RNA viral genome coated by the viral nucleoprotein N, is a critical assembly that serves as template for both mRNA synthesis and ...
Bhella   +10 more
core   +3 more sources

Efficacy and Safety of Respiratory Syncytial Virus (RSV) Prefusion F Protein Vaccine (RSVPreF3 OA) in Older Adults Over 2 RSV Seasons

open access: yesClinical Infectious Diseases
Background The adjuvanted RSV prefusion F protein–based vaccine (RSVPreF3 OA) was efficacious against RSV-related lower respiratory tract disease (RSV-LRTD) in ≥60-years-olds over 1 RSV season.
Michael G. Ison   +19 more
semanticscholar   +1 more source

Agapeic Theism: Personifying Evidence and Moral Struggle [PDF]

open access: yes, 2010
The epistemology of monotheism offered by philosophers has given inadequate attention to the kind of foundational evidence to be expected of a personal God whose moral character is ’agapeic’, or perfectly loving, toward all other agents.
Moser, Paul K.
core   +1 more source

Modified mRNA/lipid nanoparticle-based vaccines expressing respiratory syncytial virus F protein variants are immunogenic and protective in rodent models of RSV infection

open access: yesnpj Vaccines, 2020
The RSV Fusion (F) protein is a target for neutralizing antibody responses and is a focus for vaccine discovery; however, the process of RSV entry requires F to adopt a metastable prefusion form and transition to a more stable postfusion form, which ...
Amy S. Espeseth   +24 more
semanticscholar   +1 more source

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