Results 61 to 70 of about 77,778 (298)

ProSiteHunter: A Unified Framework for Sequence‐Based Prediction of Protein‐Nucleic Acid and Protein‐Protein Binding Sites

Advanced Science, EarlyView.
This study proposed a unified sequence‐based framework for protein binding site prediction, which adopted a tri‐track semantic multi‐source feature fusion strategy to effectively capture diverse macromolecular interaction sites and further improved the accuracy of antibody‐antigen interaction prediction.
Dongliang Hou, Qihang Zhen, Zexin Lv, Xinyue Cui, Suhui Wang, Minghua Hou, Zhan Zhou, Xiaogen Zhou, Guijun Zhang   +8 more
wiley   +1 more source

Replication of rHPIV3-RSV-F vectors in hamsters.

, 2020
Groups of 6 hamsters each were inoculated IN with 105 TCID50 of each indicated rHPIV3 vector, or 106 PFU of wt RSV. In addition, a previously-described construct, rB/HPIV3/GS/DS-Cav1/B3TMCT (labeled in the Figure as GS/DS-Cav1/B3TMCT) [13, 14], was ...
Sonja Surman (185609), Barney S. Graham (7400855), Xiang Liu (119470), Emerito Amaro-Carambot (185611), Xueqiao Liu (765408), Peter L. Collins (7252565), Peter D. Kwong (161423), Shirin Munir (223824), Bo Liang (450389)   +8 more
core   +1 more source

The incidence and clinical burden of respiratory syncytial virus disease identified through hospital outpatient presentations in Kenyan children [PDF]

, 2012
There is little information that describe the burden of respiratory syncytial virus (RSV) associated disease in the tropical African outpatient setting. Methods We studied a systematic sample of children aged
Bett, Ann, Okiro Emelda A., D James Nokes, Ann Bett, Bett Ann, Emelda A Okiro, Ngama Mwanajuma, Nokes D. James, Nokes, D. James, Mwanajuma Ngama, Ngama, Mwanajuma, Okiro, Emelda A.   +11 more
core   +1 more source

A Memristor‐Based In‐Memory Computing System‐on‐Chip with Efficient Depthwise Convolution

Advanced Intelligent Systems, EarlyView.
We present a memristor‐based in‐memory computing (IMC) architecture that enables efficient depthwise convolution (DWC) acceleration. Fabricated in a system‐on‐chip with crossbar arrays, the design improves memory utilization. Experimental validation demonstrates the first hardware acceleration of DWC in IMC, achieving a digital comparable inference ...
Wenhao Song, Fuxi Cai, Sangsu Park, Zhaoyan Li, Seonghun Lee, Mingyi Rao, Woohyung Choi, Seungin Shin, Yan Zhu, Sujin Chae, Myoungsub Kim, Mingche Wu, Hyejung Choi, Yuan Dao, Jaeyun Yi, Youngman Cho, Seon Yong Cha, Ning Ge, Qiangfei Xia, Soo Gil Kim, Miao Hu, J. Joshua Yang   +21 more
wiley   +1 more source

Cochlear implant

JKS (Jurnal Kedokteran Syiah Kuala), 2008
Abstrak.   Cochlear implant (Cl)  merupakan   alat  elektronik    yang  sebagiannya   ditanam    melalui    prosedur pembedahan    dan   sebagian  lagi  berada  di   luar tubuh,     memiliki    fungsi  memperbaiki   proses  rnendengar dan komunikasi ...
Teuku Husni T.R
doaj  

Respiratory Syncytial Virus Prevention through Monoclonal Antibodies: A Cross-Sectional Study on Knowledge, Attitudes, and Practices of Italian Pediatricians

Pediatric Reports, 2023
Respiratory Syncytial Virus (RSV) is a leading cause of morbidity and hospitalization in all infants. Many RSV vaccines and monoclonal antibodies (mAb) are currently under development to protect all infants, but to date preventive options are available ...
Matteo Riccò, Silvia Corrado, Milena Pia Cerviere, Silvia Ranzieri, Federico Marchesi   +4 more
doaj   +1 more source

Histidine Supplementation Stabilizes Hearing and Vision and Improves Growth in HARS1‐Related Autosomal Recessive Disorder Associated With Usher‐Like Symptoms

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Autosomal recessive HARS1‐related disorder (originally described as Usher syndrome type 3B) caused by a homozygous Y454S variant in the histidyl‐tRNA synthetase gene (HARS1) is characterized by progressive sensorineural hearing and vision loss and respiratory deterioration with risk for sudden death following febrile illnesses.
Victoria Mok Siu, Rosan Kenana, Rana Chakrabarti, Sarah D. P. Wilhelm, Joseph Andrews, Susan J. Leat, Christina Parker, Michael Miller, Leslie A. Nangle, Wendy McCaul, Ashfia Chowdhury, Natalie Hutchings, Ryan A. Adams, Lauren Guy, Mandy Rhody, Verena Juncal, Marisa I. Mendes, Desiree E. C. Smith, Gajja S. Salomons, Angelica A. Moresco, Daphne L. McCulloch, D. Holmes Morton, Ilka U. Heinemann, C. Anthony Rupar   +23 more
wiley   +1 more source

Potential for Nirsevimab use in Pakistan

Journal of the Pakistan Medical Association
Respiratory Tract Infections can be classified as upper and lower tract infections. Upper tract infections are more common such as laryngitis and pharyngitis, but the infections of lower respiratory tract are more fatal such as influenza or bronchitis ...
Muhammad Moaz, Basum Hayat
doaj   +1 more source

A phase 1, randomized, placebo-controlled study to evaluate the safety and immunogenicity of an mRNA-based RSV prefusion F protein vaccine in healthy younger and older adults

Human Vaccines & Immunotherapeutics, 2021
Respiratory Syncytial Virus (RSV) causes lower respiratory tract infections that can be severe and sometimes fatal. The risk for severe RSV infection is highest in infants and older adults.
Antonios O. Aliprantis, Christine A. Shaw, Paul Griffin, Nicholas Farinola, Radha A. Railkar, Xin Cao, Wen Liu, Jeffrey R. Sachs, Christine J. Swenson, Heather Lee, Kara S. Cox, Daniel S. Spellman, Colleen J. Winstead, Igor Smolenov, Eseng Lai, Tal Zaks, Amy S. Espeseth, Lori Panther   +17 more
doaj   +1 more source

RSV-induced innate immune responses.

, 2019
Different families of PRRs can induce innate immune responses after activation by RSV-derived PAMPs. Firstly, TLR-2, -3, -4, -6, and -7 (marked in green) are involved in the production of cytokines and chemokines upon RSV infection.
Bert Schepens (9498), Koen Sedeyn (7512218), Xavier Saelens (28372)   +2 more
core   +1 more source