Results 81 to 90 of about 77,778 (298)

Validation of a model to predict hospitalization due to RSV of infants born at 33-35 weeks' gestation

, 2010
BACKGROUND: A model to predict hospitalization due to respiratory syncytial virus (RSV) of infants born at 33- 35 weeks' gestation was developed using seven risk factors from the Spanish FLIP study "birth +/-10 weeks from the beginning of the RSV season",
European, RSV Risk Factor Study Group, LANARI, MARCELLO, Gouyon, Jean Bernard, Fullarton, John R, Carbonell Estrany, Xavier, Simões, Eric A. F, Ferdynus, Cyril   +6 more
core   +1 more source

Membrane‐Permeable Nucleoside T‐1106 Diphosphate and Triphosphate Analogues as Antiviral Pronucleotides

Chemistry – A European Journal, EarlyView.
Favipiravir (T‐705) and the non‐fluorinated counterpart (T‐1106) are antiviral agents that inhibit the RNA‐dependent RNA polymerase (RdRp) of various RNA viruses. The antiviral efficacy of nucleoside analogues is strongly dependent on their intracellular activation by cellular kinases to produce their corresponding triphosphate metabolites (T‐705‐RTP ...
Chris Meier, Duan Li, Leentje Persoons, Graciela Andrei, Robert Snoeck, Dominique Schols, Lieve Naesens, Xiao Jia   +7 more
wiley   +1 more source

Characterization of the Interaction of Known G‐quadruplex Ligands With a Minimal i‐Motif Structure

Chemistry – A European Journal, EarlyView.
The destabilization of a minimal i‐Motif (iM) structure by TMPyP4 is driven by ligand recognition of one terminal iM structural domain. ABSTRACT Peculiar genomic regions are prone to evolve transiently from double‐helix DNA to noncanonical secondary structures in response to physiological stress.
Davide Auricchio, Marko Trajkovski, Janez Plavec, Claudia Sissi   +3 more
wiley   +1 more source

Isolation and Characterization of Clinical RSV Isolates in Belgium during the Winters of 2016–2018

Viruses, 2019
Respiratory Syncytial Virus (RSV) is a very important viral pathogen in children, immunocompromised and cardiopulmonary diseased patients and the elderly.
Winke Van der Gucht, Kim Stobbelaar, Matthias Govaerts, Thomas Mangodt, Cyril Barbezange, Annelies Leemans, Benedicte De Winter, Steven Van Gucht, Guy Caljon, Louis Maes, Jozef De Dooy, Philippe Jorens, Annemieke Smet, Paul Cos, Stijn Verhulst, Peter L. Delputte   +15 more
doaj   +1 more source

From Inflammatory Bowel Disease to Cancer: Gut Microbiota–Immune Microenvironment Crosstalk and Natural Product‐Based Therapeutic Opportunities

Cancer Nexus, EarlyView.
ABSTRACT Inflammatory bowel disease (IBD), primarily Crohn's disease and ulcerative colitis, is a chronic relapsing inflammatory disorder of the gastrointestinal tract and an important risk factor for IBD‐associated cancer. Increasing evidence suggests that gut microbiota dysbiosis, epithelial barrier dysfunction, and immune microenvironment remodeling
Xue Zhang, Chongchong Gao, Rui Jiang, Zijian Wu, Jian Bai   +4 more
wiley   +1 more source

PREVALENCE OF THE RESPIRATORY SYNCYTIAL VIRUS INFECTION IN THE WINTER AND SPRING MONTHS AMONG BULGARIAN CHILDREN YOUNGERTHAN 2 YEARS OF AGE

Trakia Journal of Sciences
Lower respiratory tract infections (LRTIs) in children from 2 months to 5 years of age are significant for clinical practice and researchers because of their high incidence, risk of severe clinical course, and development of chronic complications ...
E.Kostadinova, S.Angelova
doaj   +1 more source

Assessing parenting capacity to identify RSV symptoms and the impact on their children’s health: A brief report

American Journal of Experimental and Clinical Research, 2023
Respiratory syncytial virus (RSV) is a viral infectious disease that has detrimentally affected the quality of life in children younger than 2 years of age since it was discovered in 1956. It is the major cause of lower respiratory tract illness in young
José Andres Isla Gomez, Nicholas Pereira   +1 more
doaj  

Greening the Workplace: Unlocking Green Performance Through Human Resource Management and Employee Behaviour

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT This study explores the role of green human resource management (GHRM) and employees' green behaviour (GB) in enhancing firms' green performance. Specifically, it investigates how GHRM practices contribute to improving the firm's overall environmental performance by fostering employees' GB.
María Isabel Barba‐Aragón, Raquel Sanz‐Valle, José Piñera‐Salmerón   +2 more
wiley   +1 more source

Novel Organelle‐Based Intracellular Immunity With Mechanistic and Therapeutic Implications

Barrier Immunity, EarlyView.
A conceptual framework illustrating how PAMPs/DAMPs initiate barrier, innate, adaptive, and intracellular immune responses, with organelle‐based intracellular immunity serving as a central integrator linking metabolism, inflammatory signaling, and therapeutic interventions to restore immune homeostasis.
Keman Xu, Shih‐Yu Hung, Fatma Saaoud, Ying Shao, Yifan Lu, Juanjuan Liu, Bo Yuan, Haiyan Xiang, Hong Wang, Xiaofeng Yang   +9 more
wiley   +1 more source

RSV-specific IgG against F protein antigenic sites Ø and I not correlate with disease severity.

, 2017
The abundance of antibodies in human infant plasma that bind to the prefusion F protein antigenic site Ø or the postfusion F protein antigenic site I was determined by competition with site-specific monoclonal antibodies in ELISA.
Ivy Widjaja (128545), Ronald de Groot (54924), Oliver Wicht (440906), Willem Luytjes (349214), Teun Guichelaar (3704830), Jop Jans (3704833), Gerben Ferwerda (60600), Marien I. de Jonge (527369), Inge M. L. Ahout (3704827), Cornelis A. M. de Haan (90844)   +9 more
core   +1 more source