Comparison of Media for the Detection of <i>Campylobacter jejuni</i> Using a Commercial RT-PCR System. [PDF]
Olson EG+7 more
europepmc +1 more source
The single‐layer RCP‐Chip enables rapid, multiplexed detection of SARS‐CoV‐2 RNA using RT‐LAMP and gold nanoparticle‐enhanced colorimetric readouts. After sample loading, amplification occurs within radially arranged chambers, allowing simultaneous detection of E and N genes.
Pavithra Sukumar+3 more
wiley +1 more source
Development of a Multiplex RT-PCR Detection for Six Viruses Infecting Strawberry. [PDF]
Wang Y+8 more
europepmc +1 more source
Mimicking Biochemical Traits with a Synthetic Lipid Nanoparticles SARS‐COV‐2 Model
A synthetic virus model developed using lipid nanoparticles, which incorporate encapsulated mRNA and nucleocapsid (N) protein along with surface‐conjugated spike (S) protein, mimics the characteristics of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), allowing for the advancement of diagnostic product assessment.
Ignasia Handipta Mahardika+7 more
wiley +1 more source
Quantitative Real-Time RT-PCR Verifying Gene Expression Profile of Cavitations Within Human Jaw Bone. [PDF]
Ghanaati S+3 more
europepmc +1 more source
PD‐L1 limits neuroinflammation in neovascular AMD by modulating microglial activation. Its deficiency exacerbates vascular leakage and choroidal neovascularization (CNV) via ERK signaling, while enhancing PD‐L1 reduces inflammation and neovascularization. Targeting PD‐L1 may offer a novel immunomodulatory strategy for NVAMD.
Yue Zou+7 more
wiley +1 more source
One-Step Multiplex RT-PCR Method for Detection of Melon Viruses. [PDF]
Han S+5 more
europepmc +1 more source
FUS Selectively Facilitates circRNAs Packing into Small Extracellular Vesicles within Hypoxia Neuron
This study aimed to unravel the role of FUS in the loading of functional circRNAs into neuronal sEVs under hypoxic conditions, which involves their aggregations in SGs and specific interaction between the FUS Zf_RanBP domain to regulate circRNA sorting in sEVs.
Jiankun Zang+14 more
wiley +1 more source
Development of a triplex crystal digital RT-PCR for the detection of PHEV, PRV, and CSFV. [PDF]
Shi K+7 more
europepmc +1 more source
The CRL7FBXW8 Complex Controls the Mammary Stem Cell Compartment through Regulation of NUMB Levels
In breast cancer (BC), NUMB loss of function (LOF) is common and mainly driven by protein hyper‐degradation. The CRL7FBXW8 complex is the E3 ligase responsible for NUMB degradation. Inhibition of CRL7FBXW8 in NUMB‐LOF BC cells restores NUMB levels, and decreases the number of cancer stem cells and tumorigenic ability in vivo. Targeting CRL7FBXW8 offers
Simone Sabbioni+16 more
wiley +1 more source