Results 31 to 40 of about 40,012 (261)
Receptor Tyrosine Kinase (RTK)/Ras GTPase/MAP kinase (MAPK) signaling pathways are used repeatedly during metazoan development to control many different biological processes. In the nematode Caenorhabditis elegans, two different RTKs (LET-23/EGFR and EGL-15/FGFR) are known to stimulate LET-60/Ras and a MAPK cascade consisting of the kinases LIN-45/Raf,
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On the Problem of Double-Filtering in PPP-RTK
To obtain single-receiver Global Navigation Satellite System (GNSS) parameter solutions, the PPP-RTK user-filter combines measurements with time-correlated corrections that are separately computed by the filter of an external provider. The consequence of exercising such double-filtering is that the Kalman filter’s standard assumption of having ...
Amir Khodabandeh +2 more
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High‐Speed Altitude Regulation With Neuromorphic Camera and Lightweight Embedded Computation
Neuromorphic cameras deliver rapid, high‐dynamic‐range sensing but overwhelm embedded processors at high speeds. This work presents a lightweight, optimized Lucas–Kanade optical flow method with parallelization, gyroscopic derotation, and adaptive event slicing.
Simon L. Jeger +3 more
wiley +1 more source
This paper presents a lidar‐based sensor node design and a rule‐based state observer for edge‐based traffic participant tracking. Unlike other state‐of‐the‐art methods, this state observer enables real‐time, CPU‐only edge processing without relying on machine learning approaches.
Simon Schäfer +2 more
wiley +1 more source
7000 Years of Aboriginal Mining at Sugarloaf Hill in the Riverland Region of South Australia
ABSTRACT Silcrete and chert are commonly represented in Aboriginal archaeological lithic assemblages across large parts of the southwestern Murray‐Darling Basin (MDB). In South Australia (SA), these materials were sourced from a series of quarries located along the incised course of the Murray River through the upper Riverland region.
Craig Westell +8 more
wiley +1 more source
Feedback regulation of RTK signaling in development [PDF]
Precise regulation of the amplitude and duration of receptor tyrosine kinase (RTK) signaling is critical for the execution of cellular programs and behaviors. Understanding these control mechanisms has important implications for the field of developmental biology, and in recent years, the question of how augmentation or attenuation of RTK signaling via
Neben, Cynthia L +3 more
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ABSTRACT High‐resolution and accurate synoptic images of terrestrial topography, even in densely forested areas, have proven valuable for archaeology by enabling the identification and characterization of relief patterns associated with ancient human activities. This study presents a novel approach that integrates digital terrain models (DTMs) obtained
Jhon A. Zabaleta‐Santisteban +13 more
wiley +1 more source
RTK signaling modulates the Dorsal gradient [PDF]
The dorsoventral (DV) axis of the Drosophila embryo is patterned by a nuclear gradient of the Rel family transcription factor, Dorsal (Dl), that activates or represses numerous target genes in a region-specific manner. Here, we demonstrate that signaling by receptor tyrosine kinases (RTK) reduces nuclear levels and transcriptional activity of Dl, both ...
Aharon, Helman +8 more
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ABSTRACT Ancient Olympia was one of the most important sanctuaries and the venue for the Olympic Games in Greek and Roman times. Its remains are located in the Olympia Terrace (Peloponnese, Greece) at the present‐day confluence of the rivers Alpheios and Kladeos at the base of Mount Kronos.
Sarah Bäumler +10 more
wiley +1 more source
Targeting RTK Signaling Pathways in Cancer [PDF]
The RAS/MAP kinase and the RAS/PI3K/AKT pathways play a key role in the regulation of proliferation, differentiation and survival. The induction of these pathways depends on Receptor Tyrosine Kinases (RTKs) that are activated upon ligand binding. In cancer, constitutive and aberrant activations of components of those pathways result in increased ...
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