Results 81 to 90 of about 23,003,325 (298)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
A Novel Modular Neural Architecture for Rule-based and
, 2000 Hybrid connectionist symbolic systems have been the subject of much recent research in AI. By focusing on the implementation of high-level human cognitive processes (e.g., rulebased inference) on low-level, brain-like structures (e.g., neural networks),
Christophe Giraud-carrier +2 more
core
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
A forward concurrent reasoning approach for rule-based systems using fuzzy colored Petri nets
, 2010 This paper proposes a forward concurrent reasoning method for rule-based systems using the defined fuzzy colored Petri nets (FCPN). The major differences between the proposed method and the conventional ones are described as follows.
Jiang B(姜波) +4 more
core
Wind turbine fault diagnosis based on a mivar expert system [PDF]
E3S Web of ConferencesThis research proposes a rule-driven expert system based on the mivar architecture for intelligent fault diagnosis and maintenance decision-making of wind turbines.
Linghan Dou +3 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Case-Based Reasoning for Medical and Industrial Decision Support Systems
, 2010 The amount of medical and industrial experience and knowledge is rapidly growing and it is almost impossible to be up to date with everything. The demand of decision support system (DSS) is especially important in domains where experience and knowledge ...
Ning Xiong +9 more
core +1 more source
Rule-Based Intelligence on the Semantic Web: Implications for Military Capabilities
Rules are a key element of the Semantic Web vision, promising to provide a foundation for reasoning capabilities that underpin the intelligent manipulation and exploitation of information content.
Smart, Paul R
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
StreamRule: A nonmonotonic stream reasoning system for the semantic web
, 2022 S.247-252Stream reasoning is an emerging research field focused on dynamic processing and continuous reasoning over huge volumes of streaming data. Finding the right trade-off between scalability and expressivity is a key challenge in this area.
Mileo, Alessandra +3 more
core +1 more source