Results 71 to 80 of about 23,003,325 (298)
Using Guiding Principles to Construct Effective Multiple Choice Exams to Assess Legal Reasoning
Legal Education Review, 2016 The purpose of this paper is to apply established principles for designing effective multiple choice questions to the development of multiple choice exams that can assess high level legal reasoning skills. The authors advocate for an extension of the use
Felicity Deane, Danielle Bozin
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
IEEE AccessPoster-level relation extraction (PosterRE) identifies spatial and semantic relationships among layout elements. While recent rule-based approaches improve model effectiveness, pipeline methods suffer from error propagation and end-to-end methods risk ...
Peng Chao
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Hybrid Reasoning with Rules and Constraints under Well-Founded Semantics
, 2007 The paper presents an architecture and implementation techniques for hybrid integration of normal clauses under well-founded semantics with ontologies specified in Description Logics.
Henriksson, Jakob, +2 more
core +1 more source
Applied Sciences, 2019 Today, patients generate a massive amount of health records through electronic health records (EHRs). Extracting usable knowledge of patients’ pathological conditions or diagnoses is essential for the reasoning process in rule-based systems to ...
Chao Ou-Yang +4 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Rule-based Deontic Case-based Reasoning
Proceedings of the Twentieth International Conference on Artificial Intelligence and LawThe use of machine and deep learning techniques to predict outcomes in legal proceedings is a highly debated topic among legal scholars and policymakers. These technologies have the potential for supporting judicial decision-making, assist litigants, and analyze biases within the legal process.
Antonino Rotolo +2 more
openaire +2 more sources