Results 101 to 110 of about 549,692 (299)

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky   +8 more
wiley   +1 more source

Statistical Disclosure Control for Tabular Data in R [PDF]

open access: yesRevista Română de Statistică, 2017
To perform statistical disclosure control (SDC) on tabular data is a challenging task because we need to ensure that every suppressed cell of a table has a sufficient width of a confidentiality interval under the presence of linear relations among cell ...
Kazuhiro Minami, Yutaka Abe
doaj  

COGNITIVE CONSEQUENCES OF TRANSLATIONS FOR RENDERING THE MODALITY OF LEGAL DOCUMENTS (A SEMANTIC STUDY BASED ON THE AMSTERDAM TREATY AS AN EXAMPLE)

open access: yesComparative Legilinguistics, 2009
This study aims at examining how the manifestation forms of linguistic modality, which plays a rule-constitutive role in the content of legal documents, may be changed in the process of translation. Basing on the achievements of cognitive linguistics the
Wanda WAKUŁA-KUNZ
doaj   +1 more source

Life‐Threatening Bradycardia in Anti‐NMDA‐Receptor Encephalitis and a Novel Use for Permanent Pacing

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Pediatric anti‐NMDA receptor encephalitis (pNMDARE) is an autoantibody‐mediated disorder that can cause severe autonomic dysfunction, including symptomatic bradycardia and asystole. Dysautonomia can last for years, making it very challenging to manage.
Sarah Tucker   +9 more
wiley   +1 more source

FACT CHECKING – AS THE COMPETENCE OF THE MEDIA LITERACY OF A MODERN JOURNALIST

open access: yesХабаршы Журналистика сериясы, 2019
The article talks about fact checking as the competence of media information literacy, which a modern journalist should possess. The specifics of fact- checking are analyzed, its place in the system of media and information literacy is determined ...
Мусaевa Б.   +2 more
doaj  

Cognitive Status in People With Epilepsy in the Republic of Guinea: A Prospective, Case–Control Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective People with epilepsy (PWE) may experience cognitive deficits but fail to undergo formal evaluation. This study compares cognitive status between PWE and healthy controls in the West African Republic of Guinea. Methods A cross‐sectional, case–control study was conducted in sequential recruitment phases (July 2024–July 2025) at Ignace ...
Maya L. Mastick   +14 more
wiley   +1 more source

CODE-ACCORD: A Corpus of building regulatory data for rule generation towards automatic compliance checking

open access: yesScientific Data
Automatic Compliance Checking (ACC) within the Architecture, Engineering, and Construction (AEC) sector necessitates automating the interpretation of building regulations to achieve its full potential.
Hansi Hettiarachchi   +13 more
doaj   +1 more source

Characterization of Clinical Phenotype to Glial Fibrillary Acidic Protein Concentrations in Alexander Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the concentration of glial fibrillary acidic protein (GFAP) in cerebrospinal fluid (CSF) and plasma in Alexander disease (AxD) and whether GFAP levels are predictive of disease phenotypes. Methods CSF and plasma were collected (longitudinally when available) from AxD participants and non‐AxD controls.
Amy T. Waldman   +9 more
wiley   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende   +26 more
wiley   +1 more source

Friction Coefficient Selection of the Robot Travelling Mechanism and Structure Improvement of the Driving Structure

open access: yesJixie chuandong, 2017
The checking of the robot travelling mechanism friction coefficient and a design refinement of the driving structure is carried out based on theoretical calculation and rule of thumb data,facing the creeping phenomenon of the robot travelling mechanism ...
Liao Xiaoji, Fan Qiyong
doaj  

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