Results 21 to 30 of about 3,882 (124)
Investigation of Complement Activation and Cytokine Signatures in AQP4+ NMOSD, MOGAD, and MS
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Aquaporin‐4‐IgG seropositive neuromyelitis optica spectrum disorder (AQP4+ NMOSD), myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD), and multiple sclerosis (MS) are pathophysiologically distinct neuroinflammatory disorders. Complement activation is a major mechanism of injury in AQP4+ NMOSD, whereas its role in
Angeliki G. Filippatou +23 more
wiley +1 more source
TECTB Variants Reveal Tectorial Membrane Vulnerability in Dominant Non‐Syndromic Hearing Loss
Advanced Science, EarlyView.TECTB is a non‐collagenous protein of the tectorial membrane – an extracellular matrix of the cochlea. This study identifies dominant missense variants in TECTB linked to human hereditary deafness in two unrelated families. Genetically engineered mice homozygous for one of the variants are profoundly deaf, whereas heterozygous mice have normal hearing ...
Evan B. Hale +23 more
wiley +1 more source
Rethinking Cochlear Implants: The Need for Precise Temporal Coding
Advanced Science, EarlyView.Spatial hearing relies on sensitivity to interaural temporal cues, but this sensitivity is often poorly developed in patients with cochlear implants, particularly those with early‐onset hearing loss. Rats with cochlear implants, however, demonstrate excellent temporal sensitivity, suggesting that this limitation is not inevitable.
Nicole Rosskothen‐Kuhl +1 more
wiley +1 more source
Experience Filter: Translating Heterogeneous Signals into Motion
Advanced Science, EarlyView.The Experience Filter is a signal‐agnostic framework with modality‐specific feature extraction and a modality‐agnostic shared encoding that maps heterogeneous media—music and images—into structured 3‐DoF motion. Each signal is reduced to three descriptors (intensity, dominant spectral feature, distance from neutral) and encoded into a hardware ...
Ekrem Yüksel, Alihan Bakir, Jamie Paik
wiley +1 more source
Journal of Magnetic Resonance Imaging, EarlyView.ABSTRACT Background Diffusion tensor imaging (DTI) is sensitive to white matter (WM) microstructural alterations in multiple sclerosis (MS), but duration‐defined “early MS” cohorts may be clinically heterogeneous. Purpose To investigate diffusion alterations in WM and normal‐appearing white matter (NAWM) in low‐disability MS versus healthy controls (HC)
Fabiana Bianca Hayashi Umezaki +8 more
wiley +1 more source
AIMeasuring the impact of citizen-science projects is hard because inputs are heterogeneous, mostly categorical, and sparse. We present Alquimics, a compact supervised neural network trained on one-hot project descriptors to predict impacts across five ...
Luigi Ceccaroni, Lyle Visa, Iain Visa
doaj +1 more source
Laser &Photonics Reviews, EarlyView.Chip‐based frequency combs are usually pumped from telecom wavelengths, far from the visible. This work instead pumps close to the visible with a Ti:sapphire laser ‐ the source behind the original optical frequency combs and now becoming chip‐integrable‐ and lets silicon‐nitride waveguides convert it into efficient, octave‐spanning visible‐to‐infrared ...
Abdullah Alabbadi +5 more
wiley +1 more source
Noise Suppression via Gain‐Dispersion‐Managed Nonlinear Amplification in a High‐Power Er‐Fiber Laser
Laser &Photonics Reviews, EarlyView.Gain‐dispersion‐managed nonlinear pre‐amplification simultaneously suppresses phase and intensity noise, enabling scalable high‐power fiber amplification. The system delivers 102.3 W linearly polarized pulses with 1.19 µJ energy at 85.69 MHz and compresses them to 380 fs. Near‐linear power scaling without evident saturation highlights a practical route
Mei Yang +9 more
wiley +1 more source
Widely Tunable Optical Parametric Oscillation and Visible Light Generation in 4H‐SiC Microresonators
Laser &Photonics Reviews, EarlyView.Widely separated optical parametric oscillation is demonstrated in integrated 4H‐SiC microring resonators, generating signal and idler wavelengths spanning 1200–2200 nm. The generated waves are further utilized for cascaded sum‐frequency generation, enabling wavelength conversion toward shorter wavelengths.
Yongsheng Wang +5 more
wiley +1 more source
International Journal of Mechanical System Dynamics, EarlyView.ABSTRACT Vibration isolation has long been a critical area of research, with the design of isolators based on the mechanical properties of Euler buckling beams representing one of the primary approaches. Traditionally, the focus has been on utilizing the negative stiffness characteristics of a post‐buckled Euler beam in parallel with positive stiffness
Yichang Feng +3 more
wiley +1 more source