Genomic runs of homozygosity record population history and consanguinity. [PDF]
PLoS ONE, 2010 The human genome is characterised by many runs of homozygous genotypes, where identical haplotypes were inherited from each parent. The length of each run is determined partly by the number of generations since the common ancestor: offspring of cousin ...
Mirna Kirin +5 more
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Conservation priority and run of homozygosity pattern assessment of global chicken genetic resources [PDF]
Poultry Science, 2023 : The conservation of genetic resources is becoming increasingly important for the sustainable development of the poultry industry. In the present study, we systematically analyzed the population structure, conservation priority, runs of homozygosity ...
Chaoqun Gao +9 more
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Genome-wide run of homozygosity analysis reveals candidate genomic regions associated with environmental adaptations of Tibetan native chickens [PDF]
BMC Genomics, 2022 Background In Tibet, the two most important breeds are Tibetan chicken and Lhasa white chicken, and the duo exhibit specific adaptations to the high altitude thereby supplying proteins for humans living in the plateau. These breeds are partly included in
Jingwei Yuan +7 more
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Analysis of runs of homozygosity in Yeonsan Ogye chickens using 600K single nucleotide polymorphism arrays [PDF]
Journal of Animal Science and TechnologyRuns of homozygosity (ROHs) are caused by identical haplotypes inherited from ancestors. ROHs provide useful information regarding the inbreeding rate, demographics, and selection history.
Jaewon Kim +6 more
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Genomic insights into runs of homozygosity, effective population size and selection signatures in Iranian meat and dairy sheep breeds. [PDF]
PLoS ONEGenome-wide scan for run of homozygosity (ROH) stretches, effective population size (Ne) and selection signatures can help to elucidate mechanisms of selection and pinpoint genomic regions linked with phenotypic traits.
Zohre Yousefi +4 more
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Whole-genome selection signatures identified candidate genes associated with cashmere traits in Inner Mongolia cashmere goats [PDF]
Animal BioscienceObjective Inner Mongolia cashmere goats are superior indigenous breeds developed through long-term natural selection and systematic artificial selection, which have experienced a certain intensity of selection pressure during the breeding process ...
Youjun Rong +10 more
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Genomic and Conventional Inbreeding Coefficient Estimation Using Different Estimator Models in Korean Duroc, Landrace, and Yorkshire Breeds Using 70K Porcine SNP BeadChip [PDF]
AnimalsThe purpose of this study was to estimate the homozygosity distribution and compute genomic and conventional inbreeding coefficients in three genetically diverse pig breed populations.
Kefala Taye Mekonnen +4 more
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Idiopathic Pulmonary Fibrosis: Analysis of Predisposing Variants in Patients with Familial Forms [PDF]
BiomedicinesBackground: idiopathic pulmonary fibrosis (IPF) causes progressive and irreversible changes in the lung parenchyma, leading to respiratory failure. Its pathogenesis involves several damage/repair mechanisms leading to fibrosis, whilst alterations of ...
Ilaria Stanghellini +13 more
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Homozygosity indicators in canine MHC region of the Standard Poodle and Leonberger populations [PDF]
Acta Fytotechnica et Zootechnica, 2020 Dog breeds are the leading examples of artificial selection, with sometimes extreme changes between the wolf-like phenotypes and current breeds. This increased selection pressure manifest in increased homozygosity throughout the genome, including the ...
Geena Mary Heydie Cartick
doaj +1 more source
Frontiers in Genetics, 2021 Detection of CNVs (copy number variants) and ROH (runs of homozygosity) from SNP (single nucleotide polymorphism) genotyping data is often required in genomic studies.
Jinghang Zhou +6 more
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