Results 51 to 60 of about 286,800 (345)
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Erythrocyte Phospholipid Fatty Acid Profile in High-Level Endurance Runners
Fatty acids (FAs) are the major structural component of erythrocyte membranes. Diet and physical exercise directly influence their incorporation and function.
Francisco Javier Alves-Vas +5 more
doaj +1 more source
Hire Education: Mastery, Modularization and the Workforce Revolution [PDF]
This new research identifies online competency-based learning as the solution to shifting demands for specialized workforce skills and the front runner for disrupting higher ...
Clayton M. Christensen +1 more
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The work developed a functional model (prototype) of the controller for the automated creation and management of runners’ virtual computing resources. The analysis of potential technologies for its implementation determined the choice of a combination of
Yu. Korchak, B. Mikh, Yuriy Furgala
doaj +1 more source
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Participation trends and performance analysis of Turkey’s long-distance runs between 2007-2017
Background: Long-distance running events have gained more popularity worldwide over years. However, the number of participants to such events, age and sex distribution of participants may vary by country.
MELDA PELIN YARGIC +4 more
doaj +1 more source
Correlation among runners and some results on the Lonely Runner Conjecture [PDF]
The Lonely Runner Conjecture was posed independently by Wills and Cusick and has many applications in different mathematical fields, such as diophantine approximation.
Perarnau, Guillem, Serra, Oriol
core +3 more sources
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source

