Results 61 to 70 of about 58,059 (245)
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Characteristics of Functional Movemet ScreenTM in non-competitive runners [PDF]
Objectives:The non-competitive runners is increasing, and the frequency of injuries is increasing accordingly. The purpose of this study was to clarify the characteristics of non-competitive runners’ dysfunction, asymmetry, and painful movement using the
中西, 健一郎 +11 more
core
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Marathon related death due to brainstem herniation in rehydration-related hyponatraemia: a case report [PDF]
Introduction: Identifying marathon runners at risk of neurological deterioration at the end of the race (within a large cohort complaining of exhaustion, dehydration, nausea, headache, dizziness, etc.) is challenging. Here we report a case of rehydration-
Appleby, I +5 more
core +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
Background: Anterior knee pain (AKP) is the most common injury among runners, especially in females and young runners. Because of a deficit of rehabilitation services in under-resourced communities, runners train and compete with injuries, resulting in ...
Siyabonga H. Kunene +2 more
doaj +1 more source
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
In this work we evaluated for six months 38 amateur marathons who underwent a macrocycle training, we will analyze their mood with the questionnaire POMS subscale fatigue and hormone response cortisol and blood lactate, results Emphasize a sensitivity of
luciano BUCCO Santos
doaj +2 more sources
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
ObjectiveTo explore the correlation between park view elements and their combinations on the heart rate (HR) and speed of walkers, joggers, and runners in different groups of people’s profiles and walking types, provide suggestions for the planning and ...
Nan Wang +6 more
doaj +1 more source

