Results 61 to 70 of about 1,144,325 (277)

Wheel Wear Predictions and Analyses of High-Speed Trains

open access: yesNonlinear Engineering, 2012
Wear of wheel profiles is one of the most critical issues affecting cost and performance of railway transportation systems. By altering the profile from the shape originally chosen by the designer, wear has a very large effect on vehicle dynamics, so ...
Jin X. C., Ahmadian
doaj   +1 more source

Gender differences in footwear characteristics between half and full marathons in China: a cross-sectional survey

open access: yesScientific Reports, 2023
There are concerns about the risk of injuries caused by marathons in China. Since male and female runners have different injury risks, gender differences in running shoe functionality should be further complemented.
Yuyu Xia   +9 more
doaj   +1 more source

Comparison of Two Types of Mouse Running Wheels. [PDF]

open access: yes, 2011
Voluntary wheel running of mice has been used as a measure of physical activity in a multitude of studies. The aim of this study was to validate low profile wireless running wheels (Med Associates Inc.) against solid-surface, traditionally-mounted ...
Ferguson, David   +2 more
core   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

SeRUN® study: Development of running profiles using a mixed methods analysis

open access: yesPLOS ONE, 2018
To determine profiles of urban runners based on socio-demographic, health, motivational, training characteristics and running-related beliefs and behaviours.Mixed, exploratory, sequential study with two stages: 1) quantitative, using an online survey; and 2) qualitative, using semi-structured interviews with runners from the previous stage ...
Manuela Besomi   +3 more
openaire   +5 more sources

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Sleep Matters: Profiling Sleep Patterns to Predict Sports Injuries in Recreational Runners

open access: yesApplied Sciences
Running is one of the most popular recreational sports worldwide, yet it carries a high risk of sports injuries. While various risk factors have been identified, sleep has emerged as a potentially important but understudied contributor in recreational ...
Jan de Jonge, Toon W. Taris
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Bouts of exercise elicit discordant testosterone: cortisol ratios in runners and non-runners

open access: yesArchives of Endocrinology and Metabolism, 2018
Objective: The testosterone:cortisol ratio (T:C) is suggested to be used in order to examine whether physical exercise generates either a “catabolic environment” or an “anabolic environment”.
Thiago Paes de Barros De Luccia   +4 more
doaj   +1 more source

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