Fabrication and osteogenic differentiation performance of the electrospun magnetic P(VDF-TrFE)/Fe<sub>3</sub>O<sub>4</sub> composite fibrous membranes. [PDF]
Qiang N +11 more
europepmc +1 more source
Food and Medicine Homologous Plants in Osteoporosis: A Scoping Review of Preclinical Evidence
Food and medicine homologous (FMH) plants and their bioactive compounds exhibit potential osteoprotective effects through multiple complementary mechanisms, including estrogen‐like signaling, attenuation of oxidative stress, modulation of the gut microbiota–bone axis, and regulation of autophagy.
Long Zhao +4 more
wiley +1 more source
Runx2 in the Perichondrial Osteoblasts Enhances Terminal Differentiation of Chondrocytes Through <i>Nell1</i> Induction. [PDF]
Qin X +10 more
europepmc +1 more source
Biomaterial Physical Cues as Gene Regulators for Cellular Agriculture
This review elucidates how biomaterial physical cues—ranging from matrix stiffness to remote electromagnetic fields—serve as extrinsic regulators of gene expression in cellular agriculture. By identifying central mechanotransduction pathways that bridge physical inputs to genetic remodeling, the authors propose the “Material Genome” concept: a ...
Jianuo Liu, Ye Liu
wiley +1 more source
Early Osteogenic and Stromal Marker Responses of Osteoblast-like and Bone-Marrow Stromal Cell Lines to a Hyaluronic Acid-Coated Xenogeneic Bone Graft: An Exploratory In Vitro Analysis. [PDF]
Mayer Y +5 more
europepmc +1 more source
ABSTRACT Background and Aims Osteosarcopenia, defined as the coexistence of osteoporosis and sarcopenia, is an emerging geriatric syndrome linked to the musculoskeletal decline associated with aging. It is correlated with an increased risk of falls, fractures, disability, and mortality.
Javeria Taj +6 more
wiley +1 more source
Runx2 Regulated Airway Homeostasis Is Disrupted in Asthma. [PDF]
Wang J +13 more
europepmc +1 more source
Vascular Calcification: Mechanisms, Models, and Therapies
ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu +5 more
wiley +1 more source
The effect of increased weight loading on body weight is partly dependent on Piezo1 in osteoblast-lineage cells and TrkA signaling. [PDF]
Hägg D +11 more
europepmc +1 more source
Macrophage‐MSC interactions are dynamic. Following injury, neutral (M0) macrophages arrive at the defect site and polarize towards M1 (pro‐inflammatory) macrophages, which can secrete inflammatory and cell recruitment factors. MSCs in this inflammatory defect can take on a licensed state in which they secrete a series of immunomodulatory factors that ...
Vasiliki Kolliopoulos +7 more
wiley +1 more source

