Results 211 to 220 of about 41,144 (263)

3D Printed High‐Strength Hydrogel for Dual Release of Cu2+ and Ag+ Ions to Enhance Bone Repair and Antibacterial Properties

Rare Metals, Volume 45, Issue 6, June 2026.
ABSTRACT Bone restoration is often hindered by the spatiotemporal dysregulation of immune and regenerative signals. Conventional bio‐inert implants, providing only passive support, fail to modulate this microenvironment, leading to infections and poor healing.
Zhizhong Sun, Yifei Wang, Yi Zheng, Minying Li, Longbao Feng, Ziwei Jiang, Hengrui Liu, Rui Guo, Weipeng Sun   +8 more
wiley   +1 more source

Harnessing energy metabolism for enhanced bone defect repair: Mechanisms and therapeutic strategies

VIEW, Volume 7, Issue 3, June 2026.
This review addresses the critical challenge of bone defect repair by focusing on the underexplored role of cellular energy metabolism. It synthesizes regulatory mechanisms in bone‐forming cells and sums up innovative strategies—leveraging cell derivatives, active factors, and biomimetic scaffolds—to modulate metabolism for enhanced regeneration.
Junting Li, Yulan Liu, Yuran Li, Yingjie Hua, Xinquan Jiang, Mingliang Zhou   +5 more
wiley   +1 more source

Correction to: Endothelial-to-Osteoblast Conversion maintains bone homeostasis through Kindlin-2/Piezo1/TGFβ/Runx2 axis. [PDF]

Protein Cell
europepmc   +1 more source

PRMT3-Mediated Arginine Methylation Stabilizes PCSK9 to Promote Aortic Valve Calcification. [PDF]

Circulation
Zhang X, Hao Y, Han D, Jin X, Shang X, Zhang L, Gan Z, Ye W, Wang S, Li X, Li R, Zheng K, Liu Y, Zou Z, Tao Z, Li Y, Wang Y, Xia J, Wu J.   +18 more
europepmc   +1 more source

Lanthanum Chloride in Vascular Calcification: Effects on Nano‐Hydroxyapatite and PPARγ/Wnt/β‐Catenin

FASEB BioAdvances, Volume 8, Issue 6, June 2026.
This study elucidates the anti‐calcification mechanism of lanthanum chloride (LaCl₃) in rats with chronic kidney disease (CKD) and human vascular smooth muscle cells (hVSMCs). Unlike traditional phosphate binders, trace amounts of LaCl₃ can inhibit vascular calcification without lowering serum phosphorus levels.
Ting Zhang, Jialong Qian, Li Zhu, Zhihua Zhou, Xin Wang, Yan Liang, Luyu Wang, Chunsheng Zhang, Ren Bu, Hong Liu, Changjin Xu, Gang Li   +11 more
wiley   +1 more source

Salidroside attenuates the osteoblastic differentiation of vascular smooth muscle cells via AMPK/AKT signaling pathway. [PDF]

J Mol Histol
Lu Y, Feng Y.
europepmc   +1 more source

Senescent BMSC‐Derived Thbs1 Drives Inflammaging and Impairs Bone Regeneration by Suppressing PINK1/Parkin‐Mediated Mitophagy in Macrophages

Aging Cell, Volume 25, Issue 6, June 2026.
Aging BMSC‐derived Thbs1 activates the macrophage TGF‐β/Smad3 pathway to transcriptionally repress Pink1, impairing mitophagy and causing mitochondrial ROS accumulation. This redox imbalance drives M1 polarization and IL‐6 secretion. IL‐6 feeds back to BMSCs via the JAK/STAT3 pathway to inhibit osteogenesis and upregulate Thbs1, establishing a self ...
Yifeng Xing, Jingjing Su, Yanjun Lin, Nengwen Huang, Sihui Zhang, Yuwei Zhou, Jie Lu, Weiping Chen, Kaixun He, Wenxiu Yuan, Yang Li, Geyuan Zheng, Pengyuan Hu, Dong Wu, Yanjing Ou, Jiang Chen   +15 more
wiley   +1 more source

Role and mechanism of G9A-BMP2 in calcification-induced formation of unstable plaque. [PDF]

Atheroscler Plus
Yang W, Ma Z, Cui Y, Jia S.
europepmc   +1 more source

The Critical Role of Transcription Factor RUNX2 in Bone Mechanobiology. [PDF]

Cells
Katsianou MA, Gargalionis AN, Papavassiliou KA, Margoni A, Papavassiliou AG, Basdra EK.   +5 more
europepmc   +1 more source

MECP2 Insufficiency Attenuates RUNX2-Dependent Osteoblast Differentiation via miR-126-3p/DKK1-Mediated Canonical Wnt Signaling Inhibition in Rett Syndrome. [PDF]

FASEB J
Dong S, Wang L, Kato H, Hirofuji S, Zhou Z, Ito Y, Hirofuji Y, Sato H, Kato TA, Sakai Y, Ohga S, Fukumoto S, Masuda K.   +12 more
europepmc   +1 more source