Compromised alveolar socket healing following tooth extraction upon Aff4 knockout is caused by suppressed osteogenic capacity of orofacial mesenchymal stem cells, which results from defective AMPK‐mediated mitophagy. ABSTRACT Repair of maxillofacial bone defects presents significant clinical challenges.
Li Zhu +7 more
wiley +1 more source
Alterations of bone proteins in medication‐related osteonecrosis of the jaw
Abstract Changes in the protein expression pattern of osteoblastic lineage cells from the alveolar bone (OLAB) during medication‐related osteonecrosis of the jaw (MRONJ) have rarely been investigated. This lack of information is partly because of the limited availability of healthy samples and the lack of human alveolar bone cell lines for research ...
Andrea Schubert +6 more
wiley +1 more source
MACF1 Mediates the Impairment of Mechanical Unloading on Osteoblast Differentiation via F-Actin/ERK/Runx2 Axis. [PDF]
Hu L +7 more
europepmc +1 more source
Abstract This systematic review investigated the osteogenic effects of platelet concentrate (PRF/PRP) when combined with non‐autogenous graft materials in sinus lift procedures. Key characteristics assessed included platelet concentration, total platelet dose, leukocyte content, and fibrin‐network structure.
Olav Kansgar Straum +4 more
wiley +1 more source
Role of ATOH8 in Mitigating Cardiac Fibrosis in Heart Failure via Inhibition of the Transcriptional Repression of Smad7 by RUNX2. [PDF]
Chen C +8 more
europepmc +1 more source
Cutaneous involvement by myeloid leukaemias: challenging cases with important implications
Myeloid leukaemias and precursors involving the skin are often challenging to diagnose with varied and overlapping clinical and histopathologic features. Nonetheless, they are critical for pathologists to recognize and accurately classify. This review discusses the clinical, histopathological and genetic features of myelodysplasia cutis (A) and ...
Alexandra C. Hristov
wiley +1 more source
Epigenetic regulatory networks in the pathogenesis and treatment of osteoporosis subtypes. [PDF]
Ren Z +8 more
europepmc +1 more source
A description of dental microanatomy and implantation geometry in Chamaeleonidae
A reassessment of the dental histology in adult chamaeleons reveals the presence of periodontal ligament. Alongside alveolar bone and cementum, these tissues together constitute a compacted and remodelled tripartite periodontium. Our findings include the novel observation of plicidentine‐like protuberances of dentine within underlying bone.
Giles D. Sukkert +4 more
wiley +1 more source
Soluble Epoxide Hydrolase Inhibition Accelerates Early Bone Repair in Critical-Size Calvarial Defects and Requires ENPP1 Activity for Osteoblast Mineralisation In Vitro. [PDF]
Vargas BSF +13 more
europepmc +1 more source
Abstract Purpose Few studies have explored the bone response in dental implant sites prepared using a piezoelectric device, indicating moderate effectiveness in enhancing secondary stability and osteogenesis. This study seeks to expand our understanding of the changes in biological, clinical, and radiographic parameters, during the initial phases of ...
Gianmario Schierano +8 more
wiley +1 more source

