Results 251 to 260 of about 66,303 (295)

Diallyl Disulfide Mitigates LPS-Induced Inhibition of Osteogenic Differentiation and Alleviates Inflammatory Bone Loss via PI3K/AKT Signaling Pathway. [PDF]

Drug Des Devel Ther
Wu J, Guo D, Du Y, Wang Z, Li S, Xu H, Chu X, Gao X, Li L, Fei J.   +9 more
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Progress on the mechanism of Polycystin-1 in bone remodeling. [PDF]

Front Cell Dev Biol
Guo J, Hu G, Li X, Yi X, Chang B, Li T.
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Comprehensive multi-omics analysis reveals RUNX1's prognostic value, immune associations, and MUC13-Mediated mechanistic role in hepatocellular carcinoma pathogenesis. [PDF]

Biochem Biophys Rep
ALMatrafi TA.
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Transcriptional dynamics of CD8⁺ T-cell exhaustion in immune checkpoint inhibitor resistance at single-cell resolution. [PDF]

Mol Cancer
Tseng TY, Hsieh CH, Huang HC, Wu YC, Hsu C, Hsu CL, Ou DL, Juan HF.   +7 more
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RUNX2 and Osteosarcoma

Anti-Cancer Agents in Medicinal Chemistry, 2015
Osteosarcoma (OS) is the most common pediatric bone cancer in children and young adults. Previous studies have suggested the importance of osteoblast activity in OS tumorigenesis and metastasis, as OS is characterized by abnormal bone formation, while osteoblast is the predominant cell type both in OS and in metastatic tumor tissues.
Na, Li, Dongwei, Luo, Xiaoxia, Hu, Wei, Luo, Guanghua, Lei, Qian, Wang, Ting, Zhu, Junxia, Gu, Yaojuan, Lu, Qiping, Zheng   +9 more
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RUNX2 Promotes Malignant Progression in Glioma

Neurochemical Research, 2018
Glioblastoma (GBM) is the most aggressive and lethal form of brain tumor. However, therapeutic strategies against malignant gliomas have not been completely established. Runt-related transcription factor 2 (Runx2) is an essential gene for skeletal development but its regulatory role in the malignant progression of glioma remains unclear.
Daisuke, Yamada, Koichi, Fujikawa, Kenji, Kawabe, Takuya, Furuta, Mitsutoshi, Nakada, Takeshi, Takarada   +5 more
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Control of Tooth Morphogenesis by Runx2

Critical Reviews™ in Eukaryotic Gene Expression, 2006
Odontogenesis is a complex process in which the interplay of signaling cascades of the epithelium and mesenchyme is critical. Evidence for the involvement of Runx2--a well-known osteogenic master transcription factor--in odontogenesis, has been accumulating.
Hyun-Mo, Ryoo, Xiu-Ping, Wang
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Transcriptional co-repressors of Runx2

Journal of Cellular Biochemistry, 2006
Runx2 is an essential transcription factor for skeletal mineralization because it stimulates osteoblast differentiation of mesenchymal stem cells, promotes chondrocyte hypertrophy, and contributes to endothelial cell migration and vascular invasion of developing bones.
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