Results 111 to 120 of about 549,283 (299)

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp, Ludwig Karrasch, Helena Breitenstein, Andreas Straube, Katharina Kamm   +4 more
wiley   +1 more source

Microcrack monitoring and fracture evolution of coal and rock using integrated acoustic emission and digital image correlation techniques

Scientific Reports
The mechanical properties of a coal–rock body were examined through uniaxial compression tests, and the rupture process of the coal–rock body was monitored in real time using a combined acoustic emission (AE) monitoring system and a digital image ...
Zhihui Zhao, Jinhu Yang, Yueming Kang, Yong Xiao   +3 more
doaj   +1 more source

Effect of grain refinement on the stress rupture property of K447A alloy

Journal of Aeronautical Materials
Grain refinement can effectively enhance mechanical properties of materials at low and medium temperatures，however，it may weaken the stress rupture property above the equicohesive temperature. To study the effect of grain refinement on the stress rupture
HU Pinpin, DING Ning, WANG Yue, LI Yanjia, ZHANG Mingjun, XIAO Chengbo, HE Jinshan, WANG Xitao   +7 more
doaj   +1 more source

Thermal Breakage and Self-Healing of a Polymer Chain under Tensile Stress

, 2010
We consider the thermal breakage of a tethered polymer chain of discrete segments coupled by Morse potentials under constant tensile stress. The chain dynamics at the onset of fracture is studied analytically by Kramers-Langer multidimensional theory and
Dimitrov, D. I., Ghosh, A., Milchev, A., Rostiashvili, V. G., Vilgis, T. A.   +4 more
core   +1 more source

Choroid Plexus Enlargement and USPIO‐Based Inflammatory Feature in Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The choroid plexus (CP) is a key component of the blood–cerebrospinal fluid barrier (BCSFB), but its mechanism of action in cerebral small vessel disease (CSVD) remains unclear. This study investigated CP volume (CPV) alterations and their association with conventional imaging markers in CSVD and explored the underlying role of ...
Yongqiang Qu, Xiaoning Ren, Cuihua Fan, Chun Li, Lijie Zhang, Zaiqiang Zhang, Shaowu Li, Zhongmeng Lai, Bin Cai, Ying Fu, Yi Lin, Zhibao Zhu   +11 more
wiley   +1 more source

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento, Daniela F. Santos, Tuane C. R. G. Vieira, Tiago F. Outeiro   +3 more
wiley   +1 more source

Comprehensive Assessment of Arterial, Tissue, and Venous Collaterals for Evaluating the Infarct Growth Rate: The Multimodal Collateral Score

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Collaterals are crucial factors that influence the infarct growth rate (IGR). We aimed to determine whether a comprehensive multimodal collateral score (MCS), incorporating collateral assessment at the arterial, tissue, and venous levels, is associated with functional independence and provides incremental prognostic value over ...
Giorgio Busto, Umberto Pensato, Ilaria Casetta, Giorgio U. Marcello, Angelo Barra, Anna Poggesi, Edoardo Carlesi, Sara Mancini, Andrea Ginestroni, Vittorio Miele, Alessandro Padovani, Andrea Morotti, Enrico Fainardi   +12 more
wiley   +1 more source

Verification of high rupture speed of the 1990 Luzon earthquake, Philippines from Taiwan seismic network observations

Geoscience Letters
On July 16, 1990, a Mw 7.7 earthquake struck central Luzon, Philippines. The event produced more than 100 km of surface rupture along the Philippine Fault system. Seismologists conducted detailed investigations of the overall source rupture process using
Bor-Shouh Huang, Bartolome C. Bautista, Po-Fei Chen, Chin-Shang Ku, Ishmael Narag, Emi Ulfiana, Arnaldo Melosantos, Bryan Nadimpally   +7 more
doaj   +1 more source

Polymer chain scission at constant tension - an example of force-induced collective behaviour

, 2011
The breakage of a polymer chain of segments, coupled by anharmonic bonds with applied constant external tensile force is studied by means of Molecular Dynamics simulation.
Milchev, A., Paturej, J., Rostiashvili, V. G., Vilgis, T. A.   +3 more
core   +1 more source

Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and 1‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study

Arthritis Care &Research, EarlyView.
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension phase).
Fabrizio De Benedetti, Inmaculada C. Penadés, Irina Nikishina, Ivan Foeldvari, Alberto J. Spindler, Anna Kozlova, Nadina Rubio‐Pérez, Pierre Quartier, Zbigniew Żuber, Raul Barria, Daniel Clemente, Gabriel V. Cornejo, Katherine Marzan, Nancy Liu, Christine Xu, Stephen DiMartino, Angeliki Giannelou, Fei Cao‐Ghoul, Bolanle Akinlade, Lydie Baret‐Cormel   +19 more
wiley   +1 more source