Results 151 to 160 of about 38,942 (269)

Targeting KDM3B Elicits Anti‐tumor Immunity by Alleviating SHP1–mediated STING Suppression in Triple–Negative Breast Cancer

Advanced Science, EarlyView.
P3FI–90 treatment targets KDM3B, reshapes the epigenetic landscape, and suppresses SHP1 expression, thereby activating STING–TBK1–IRF3–type I IFN signaling pathway. Consequently, CD8+ T cells are recruited to the tumor site and activated to produce IFN–γ and GZMB, leading to the killing of TNBC cells.
Xiaolong Wang, Wenhao Li, Yifei Wang, Ning Zhang, Bing Chen, Wenjing Zhao, Lijuan Wang, Dan Luo, Qifeng Yang   +8 more
wiley   +1 more source

Arginine-Tryptophan Peptides Enhancing Antibacterial and Anticancer Effects of Ruthenium(II) Polypyridyl Complex Photosensitizers. [PDF]

ACS Omega
Ng XY, Fong KW, Kiew LV, Chung PY, Liew YK, Delsuc N, Lim WM, Zulkefeli M, Low ML.   +8 more
europepmc   +1 more source

Magnetically Boosted Water‐Splitting Performance in Metallic Glasses

Advanced Science, EarlyView.
A strategy for boosting water electrolysis efficiency using ultralow magnetic fields on soft‐magnetic MG wires is reported. Ni40Fe40P20 metallic glass exhibits superior overall water‐splitting performance (1.51 V @ 1000 mA cm−2) at 100 Oe, enabled by spin polarization in periodic surface magnetic domains to enhance orbital hybridization and net spin ...
Chaoqun Pei, Zheng‐Jie Chen, Yuyang Qian, Zhichao Lu, Dong Ma, Jiang Ma, Tao Feng, Jing Peng, Baoan Sun, Weihua Wang   +9 more
wiley   +1 more source

Protoporphyrin IX-Derived Ruthenium(II) Complexes for Photodynamic Therapy in Gastric Cancer Cells. [PDF]

Inorg Chem
Restrepo-Acevedo A, Murillo MI, Orvain C, Thibaudeau C, Recberlik S, Verget L, Gómez Vidales V, Gaiddon C, Mellitzer G, Le Lagadec R.   +9 more
europepmc   +1 more source

Beyond d‐Band Catalysis: A Critical Review and Descriptor Framework for Rare‐Earth Engineering in Lithium–Sulfur Batteries

Advanced Science, EarlyView.
Rare‐earth catalysts regulate lithium–sulfur battery chemistry through f‐orbital–mediated interactions, enabling simultaneous polysulfide adsorption and catalytic conversion on conductive carbon hosts. This synergistic control suppresses the shuttle effect, accelerates redox kinetics, and guides stable Li2S nucleation, providing a mechanistic framework
Fan Wang, Shihzad Shakil, Guozhi Wu, Jiarui Huang, Hanhui Lei, Terence Xiaoteng Liu   +5 more
wiley   +1 more source

Radical Electroprecipitation from a Water|Oil|Electrode Interface Prolongs "Electro"Chemiluminescence of the Tris(2,2'-bipyridyl)Ruthenium(II) and Benzoyl Peroxide System by 10³. [PDF]

Angew Chem Int Ed Engl
Carrel DM, Layman BR, Hill ML, Dick JE.
europepmc   +1 more source

Construction of Sabatier Volcanoes for CO2 Hydrogenation to C1‐2 Oxygenates Using Data‐Efficient Machine Learning

Advanced Science, EarlyView.
A new data‐efficient framework combining DFT calculations, a neural network model, and automated graph analysis of catalytic reaction networks is proposed and applied to CO2 hydrogenation on transition metal nanoparticles. The analysis shows how efficient C2 oxygenate production requires a balance between CHx formation, C–C coupling, protonation, and ...
Mikhail V. Polynski, Sergey M. Kozlov
wiley   +1 more source

Naphthyl-Substituted Ruthenium(II)-Arene Complexes: Exploring the Impact of Binding Modes on Cytotoxicity in Cancer and Normal Cell Lines. [PDF]

Bioinorg Chem Appl
Kavukcu SB, Vatansever HS, Ilhan S, Türkmen H.   +3 more
europepmc   +1 more source

Targeting DNGR‐1 with Fangchinoline Elevates Dendritic Cell Antigen Cross‐Presentation‐Mediated Antitumor Immunity in Melanoma

Advanced Science, EarlyView.
Fangchinoline is identified as a small‐molecule DNGR‐1 modulator that enhances dendritic‐cell cross‐presentation of tumor antigens. By engaging DNGR‐1 and activating Syk–Nox2 signaling, it promotes phagosomal ROS, antigen escape, MHC‐I presentation, and CD8+ T‐cell priming, thereby strengthening antitumor immunity and sensitizing tumors to PD‐1 ...
Yuan Liao, Zhenyang Ren, Jing Zhou, He Luo, Yuling Li, Dan Chen, Yuxiao Jiang, Canzhe Li, Mengyi Zheng, Anqi Li, Yao Wang, Yang Zhang, Dingye Wang, Yanjun Jiang, Jiangyong Gu, Biaoyan Du, Yafei Shi, Fang Liu, Jianyong Xiao, Kun Wang   +19 more
wiley   +1 more source

Inverse Correlation between Endoplasmic Reticulum Stress Intensity and Antitumor Immune Response with Ruthenium(II)-Based Photosensitizers for the Photodynamic Therapy of Head and Neck Squamous Cell Carcinoma. [PDF]

J Med Chem
Thibaudeau C, Bour C, Scarpi-Luttenauer M, Mesdom P, Karges J, Gandioso A, Zhou L, Harlepp S, Detappe A, Burgy M, Martin S, Mellitzer G, Gaiddon C, Gasser G, Jung AC.   +14 more
europepmc   +1 more source