The NADPH oxidase NOX4 regulates redox and metabolic homeostasis preventing HCC progression
Loss of NOX4 in HCC tumor cells induces metabolic reprogramming in a Nrf2/MYC‐dependent manner to promote HCC progression. Abstract Background and Aims The NADPH oxidase NOX4 plays a tumor‐suppressor function in HCC. Silencing NOX4 confers higher proliferative and migratory capacity to HCC cells and increases their in vivo tumorigenic potential in ...
Irene Peñuelas‐Haro +14 more
wiley +1 more source
Rutting vocal display in male impala (Aepyceros melampus) and overlap with alarm context
Background The rutting vocal display of male impala Aepyceros melampus is unique for its complexity among ruminants. This study investigates bouts of rutting calls produced towards potential mates and rival males by free-ranging male impala in Namibia ...
Ilya A. Volodin +2 more
doaj +1 more source
Effects of reproductive status, social rank, sex and group size on vigilance patterns in Przewalski's gazelle. [PDF]
Quantifying vigilance and exploring the underlying mechanisms has been the subject of numerous studies. Less attention has focused on the complex interplay between contributing factors such as reproductive status, social rank, sex and group size ...
Chunlin Li +6 more
doaj +1 more source
Asphalt pavement rutting model in seasonal frozen area
Effective prediction of rutting diseases in seasonal frozen area is helpful for comprehensive evaluation of asphalt pavement performance. In this paper, based on the Mechanical-Experienced Pavement Design Guide (MEPDG) theory, the rutting prediction ...
Zhang Lina, He Dongpo, Zhao Qianqian
doaj +1 more source
A review of rutting in asphalt concrete pavement
Undoubtedly, rutting in asphalt concrete pavement is considered a major dilemma in terms of pavement performance and safety faced by road users as well as the road authorities. Rutting is a bowl-shaped depression in the wheel paths that develop gradually
Albayati Amjad H.
doaj +1 more source
The rutting model of semi-rigid asphalt pavement based on RIOHTRACK full-scale track
Semi-rigid asphalt pavement has a wide range of application cases and data bases, and rutting is a typical failure mode of semi-rigid asphalt pavement. The establishment of an accurate rutting depth prediction model is of great significance to pavement ...
Bo Kou, Jinde Cao , Wei Huang, Tao Ma
doaj +1 more source
Roaring high and low: composition and possible functions of the Iberian stag's vocal repertoire [PDF]
We provide a detailed description of the rutting vocalisations of free-ranging male Iberian deer (Cervus elaphus hispanicus, Hilzheimer 1909), a geographically isolated and morphologically differentiated subspecies of red deer Cervus elaphus.
A Marshall +70 more
core +7 more sources
Evaluation of Stiffness to Predict Rutting Resistance of Hot-Mix Asphalt: a Canadian Case Study
This paper investigates the relationship between the stiffness and rutting resistance of hot-mix asphalt. Ten different types of hot-mix asphalt were examined.
Md. Safiuddin +2 more
doaj +1 more source
With the rapid increase in vehicles, the load on the asphalt pavement increases, which aggravates the appearance of rutting disease. In order to establish an effective rutting depth prediction model, this study carried out accelerated loading tests (ALT)
Kun Chen +3 more
doaj +1 more source
Improving safety of runway overrun through the correct numerical evaluation of rutting in Cleared and Graded Areas [PDF]
Aircraft overrun is potentially very dangerous to human life. Statistics show that overrun is mainly due to human errors causing loss of control in wheel alignment, high approach speed, and long touchdown.
Benedetto, Andrea +2 more
core +1 more source

