The NADPH oxidase NOX4 regulates redox and metabolic homeostasis preventing HCC progression
Loss of NOX4 in HCC tumor cells induces metabolic reprogramming in a Nrf2/MYC‐dependent manner to promote HCC progression. Abstract Background and Aims The NADPH oxidase NOX4 plays a tumor‐suppressor function in HCC. Silencing NOX4 confers higher proliferative and migratory capacity to HCC cells and increases their in vivo tumorigenic potential in ...
Irene Peñuelas‐Haro +14 more
wiley +1 more source
Study on the Modeling Method Suitable for Pavement Rutting
A paved road surface is in contact with a vehicle directly through its tire therefore its condition is closely associated with vehicle running 1) . It also greatly affects road user’s ride quality, safety and the living environment of roadside resident.
Tomiyama, Kazuya +2 more
openaire +3 more sources
3D finite element modeling to predict the foamed sulfur asphalt marl soil mixes rutting behavior
This research was executed to predict and discuss the rutting behavior of marl soil treated with foamed sulfur asphalt (FSA) with the mixtures of the same soil treated with standard foamed asphalt (FA) for road bases structure.
Gamil. M.S. Abdullah
doaj +1 more source
Artificial Intelligence Prediction of Rutting and Fatigue Parameters in Modified Asphalt Binders
The complex shear modulus (G*) and phase angle (δ) are fundamental viscoelastic rheological properties used in the estimation of rutting and fatigue pavement distress in asphalt binder.
Ikenna D. Uwanuakwa +5 more
doaj +1 more source
Asphalt pavement rutting model in seasonal frozen area
Effective prediction of rutting diseases in seasonal frozen area is helpful for comprehensive evaluation of asphalt pavement performance. In this paper, based on the Mechanical-Experienced Pavement Design Guide (MEPDG) theory, the rutting prediction model of asphalt pavement in the seasonal frozen area is established by using the measured rutting data ...
Zhang, Lina, He, Dongpo, Zhao, Qianqian
openaire +2 more sources
Prediction of Permanent Deformation of Foamed and Emulsified Sulfur Asphalt Soils Mixes
This paper presents a study carried out to evaluate and compare the permanent deformation of marginal soils. Under consideration were marl, sabkha and dune sand stabilized with foamed and emulsified sulfur asphalt (FSA, ESA) with mixes of the same soils ...
H.I. Al-Abdul Wahhab, G.M.S. Abdullah
doaj +1 more source
Evaluation of road safety installations with a model rutting tester [PDF]
Passively lighted reflector systems are used increasingly for improving pedestrian security. They are glued on the road surface in front of pedestrian crossings and are exposed to any kind of traffic loading. In order to achieve durable and reliable functioning of these reflectors, the mechanical behaviour of the road reflectors themselves, as well as ...
K. Sokolov +3 more
openaire +2 more sources
Calculation Method for Traffic Load-Induced Permanent Deformation in Soils under Flexible Pavements
Rutting is one of the most common types of distress in flexible pavement structures. There are two fundamental methods of designing pavement structures: conventional empirical methods and analytical approaches.
Mate Janos Vamos, Janos Szendefy
doaj +1 more source
Modeling the Rutting Kinetics of the Sulfur-extended Asphalt
Abstract In the present article we have summarized the rutting resistance testing results of the sulfur extended asphalt. The results were obtained with help of three different methods – RU GOST 12801-98, AASHTO TP 63 and AASHTO T 324. It was confirmed that AASHTO test results adequately describe the ability of asphalt concrete to resist irreversible
Gladkikh, Vitaliy +3 more
openaire +1 more source
Rutting Prediction Models in Holistic Concept to Sustainability of Semi-Rigid Pavements
Authors have long been guided by the following premise in their research, educational, professional and publishing activities. Components of the Integrated Transport Infrastructure (ITI) of Slovakia, including roads, should be designed, built, managed ...
Sramek Juraj +4 more
doaj +1 more source

