Results 21 to 30 of about 41,762 (99)

Mechanisms and therapeutic implications of RTA 408, an activator of Nrf2, in subarachnoid hemorrhage–induced delayed cerebral vasospasm and secondary brain injury

PLoS ONE, 2020
Objectives More and more evidence suggests oxidative stress and inflammation contribute importantly to subarachnoid hemorrhage (SAH)-induced cerebral vasospasm and secondary brain injury.
T. Tsai, Szu-Huai Lin, Chieh-Hsin Wu, Y. Tsai, Sheau-Fang Yang, Chih-Lung Lin   +5 more
semanticscholar   +1 more source

The development and validation of the Hopelessness Inventory-5 in a community-based sample

Journal of Affective Disorders Reports, 2023
Background: Hopelessness is an important risk factor for depression and suicide. However, few suitable measures exist for use in the general population, limiting research testing aetiological models.
Yushi Wang, Philip J. Batterham, Tegan Cruwys, Alison L. Calear   +3 more
doaj   +1 more source

Association of markers of inflammation and intestinal permeability in suicidal patients with major mood disorders

Journal of Affective Disorders Reports, 2023
Background: Patients with major mood disorders are at high risk of suicidal behavior compared to the general population. Suicide is a public health concern, accounting for around 1.2% of deaths worldwide.
Julie Z. Brouillet, Margherita Boltri, Aiste Lengvenyte, Mohamed Lajnef, Jean-Romain Richard, Caroline Barrau, Robertas Strumila, Manon Coyac, Ching-Lien Wu, Wahid Boukouaci, Sobika Sugunasabesan, Jihène Bouassida, Sébastien Guillaume, Maude Sénèque, Emilie Olié, Marion Leboyer, Philippe Courtet, Ryad Tamouza   +17 more
doaj   +1 more source

Bipolar disorder longitudinal study in Nigeria – Preliminary data on demographic and clinical findings of the study cohort

Journal of Affective Disorders Reports, 2023
Background: Bipolar disorder, severe mood disorder characterised by its ability to swing between two contrasting poles of low and elated mood with a return to relatively normal level of functioning, has a lifetime prevalence of up to 2.4%, a heterogenous
Frances Nkechi Adiukwu, Olufisayo Adesokun, Izuchukwu Metu, Isoboye Jack, Collins Ekwubiri, joy Iyanuoluwapo Igbari, Chidozie Chukwujekwu   +6 more
doaj   +1 more source

Worries about the COVID-19 pandemic and the dynamic regulation of emotions in the general population: A network analysis study

Journal of Affective Disorders Reports, 2023
Background: The impact of the COVID-19 pandemic on mental health has been widely reported. Yet, little remains known about the psychological mechanisms associated with changes in mental well-being during the currently ongoing pandemic.
Stella D. Voulgaropoulou, Wolfgang Viechtbauer, Sjacko Sobczak, Thérèse van Amelsvoort, Dennis Hernaus   +4 more
doaj   +1 more source

Concurrent transcranial magnetic stimulation and electroencephalography measures are associated with antidepressant response from rTMS treatment for depression

Journal of Affective Disorders Reports, 2023
Background: Response rates to repetitive transcranial magnetic stimulation (rTMS) for depression are 25-45%. Participant features obtained prior to treatment that are associated with response to rTMS may be clinically useful.
Neil W. Bailey, Kate E. Hoy, Caley M. Sullivan, Brienna Allman, Nigel C. Rogasch, Zafiris J. Daskalakis, Paul B Fitzgerald   +6 more
doaj   +1 more source

A combination of 7-ketocholesterol, lysosphingomyelin and bile acid-408 to diagnose Niemann-Pick disease type C using LC-MS/MS

PLoS ONE, 2020
Background Niemann-Pick disease type C (NPC) is an autosomal recessive disorder caused by mutations of NPC1 or NPC2, which encode the proteins that are responsible for intracellular cholesterol trafficking.
Chen Wu, T. Iwamoto, M. A. Hossain, Keiko Akiyama, Junko Igarashi, T. Miyajima, Y. Eto   +6 more
semanticscholar   +1 more source

A qualitative study of patients' experience of ketamine treatment for depression: The ‘Ketamine and me’ project

Journal of Affective Disorders Reports, 2021
Background: There has been a lack of in-depth interviews investigating patient experience of ketamine treatment for depression. We examined participants’ pathways to receiving ketamine infusion to treat their depression, and their responses to, lived ...
Chris Griffiths, Kate Walker, Isabel Reid, Ksenija Maravic da Silva, Alex O'Neill-Kerr   +4 more
doaj   +1 more source

Depression and time perspectives in patients with brain tumors: Novel measurements in the circle test

Journal of Affective Disorders Reports, 2021
Background: Tumors trigger both depression and anxiety about death because they can be terminal. However, the relationship between depression and time perspective in patients with life-threatening diseases remains unclear.
Yayoi Shigemune, Shoko Saito, Kentaro Hiromitsu, Kanako Hamamoto, Ryuta Ochi, Nobusada Shinoura, Ryoji Yamada, Akira Midorikawa   +7 more
doaj   +1 more source

Genetic influences on eight psychiatric disorders based on family data of 4 408 646 full and half-siblings, and genetic data of 333 748 cases and controls

Psychological Medicine, 2018
Background Most studies underline the contribution of heritable factors for psychiatric disorders. However, heritability estimates depend on the population under study, diagnostic instruments, and study designs that each has its inherent assumptions ...
E. Pettersson, P. Lichtenstein, H. Larsson, H. Larsson, Jie Song, A. Agrawal, A. Børglum, C. Bulik, C. Bulik, M. J. Daly, M. J. Daly, L. Davis, D. Demontis, H. Edenberg, J. Grove, J. Gelernter, B. Neale, B. Neale, A. Pardiñas, E. Stahl, J. Walters, R. Walters, R. Walters, P. Sullivan, Patrick F. Sullivan, D. Posthuma, T. Polderman   +26 more
semanticscholar   +1 more source