Results 201 to 210 of about 3,057,586 (215)

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Temporal sleep spindle clustering and slow-oscillation coupling in motor memory consolidation and generalization. [PDF]

Commun Biol
Conessa A, Léger D, Boutin A.
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Machine learning reveals sequence and methylation determinants of SaCas9-PAM interactions in bacteria. [PDF]

Nucleic Acids Res
Ham DT, Browne TS, Zhang CQ, Foo GW, Uruthirapathy AS, Gloor GB, Edgell DR.   +6 more
europepmc   +1 more source

Free-breathing three-dimensional whole-heart adiabatic T1ρ mapping for non-contrast tissue characterization at 0.55T. [PDF]

J Cardiovasc Magn Reson
Si D, Crabb MG, Littlewood SJ, Kunze KP, Prieto C, Botnar RM.   +5 more
europepmc   +1 more source

BPSS: a Nextflow pipeline for Bacterial Peptide Sequence Selection to detect protein diversity. [PDF]

Bioinformatics
Bastien S, François P, Moussadeq S, Lemoine J, Moreau K, Vandenesch F.   +5 more
europepmc   +1 more source

Histopathologic and Genomic Characterization of a Novel Caprine Astrovirus Identified in a Boer Goat Kid in Illinois, United States. [PDF]

Viruses
Li J, Baumgartner W, Wang L.
europepmc   +1 more source

RaptScore: a large language model-based algorithm for versatile aptamer evaluation. [PDF]

Nucleic Acids Res
Kimura-Yamazaki A, Adachi T, Nakamura S, Nakamura Y, Hamada M.   +4 more
europepmc   +1 more source