Results 31 to 40 of about 2,851 (147)
Angewandte Chemie, Volume 138, Issue 24, 8 June 2026.Diese Studie beschreibt die Herstellung und Eigenschaften einer neuen Familie von o‐Terphenyl‐basierten Makrozyklen, TP[n] (n = 2‐8). Der Trimer bindet Phenylalanin in Wasser sehr effizient und ist dabei zehnmal selektiver als bei anderen Aminosäuren und aromatischen Neurotransmittern.
Swapnil Ghule +5 more
wiley +1 more source
Possible mechanisms underlying wheel-running-induced hypotensive effects
Journal of Physical Fitness and Sports Medicine, 2014 Physical activity of moderate intensity, like walking and jogging, can reduce the risk of developing metabolic syndrome and improve hypertension. However, such anti-hypertensive effects have yet to be fully studied.
Susumu Sakata +2 more
doaj +1 more source
Immune–proteo–metabolomic changes link to Aβ and tau pathology in Alzheimer disease
Alzheimer's &Dementia, Volume 22, Issue 4, April 2026.Abstract INTRODUCTION Tryptophan metabolism is increasingly implicated in Alzheimer's disease (AD), particularly through aryl hydrocarbon receptor (AhR) ligands that influence neuroinflammation. However, their relationships with core AD pathology—amyloid‐β (A) and tau (T) deposition—and associated immune–proteomic alterations remain unclear. METHODS We
Meng Wang +21 more
wiley +1 more source
Transcriptional evidence for the role of chronic venlafaxine treatment in neurotrophic signaling and neuroplasticity including also Glutamatergic [corrected] - and insulin-mediated neuronal processes. [PDF]
PLoS ONE, 2014 Venlafaxine (VLX), a serotonine-noradrenaline reuptake inhibitor, is one of the most commonly used antidepressant drugs in clinical practice for the treatment of major depressive disorder (MDD).
Viola Tamási +7 more
doaj +1 more source
Genetic Epidemiology, Volume 49, Issue 5, July 2025.ABSTRACT Genetic selection occurs at different stages before a successful birth. The genetic makeup of a couple may influence the likelihood of needing assisted reproductive technology (ART) to achieve conception. However, frequent early fetal losses may also be perceived as reduced couple fertility and may thus be a contributing factor to the need for
Siri N. Skodvin +9 more
wiley +1 more source
Régulation de la biosynthèse des estrogènes par la sérotonine dans le trophoblaste humain : effets des antidépresseurs inhibiteurs de la recapture de la sérotonine [PDF]
, 2019 La dépression affecte jusqu'à 20% des femmes enceintes et les principaux traitements pharmacologiques agissent sur le transporteur de la sérotonine (ISRS; inhibiteurs sélectifs de la recapture de la sérotonine).
Hudon-Thibeault, Andrée-Anne
core +2 more sources
Angewandte Chemie, Volume 137, Issue 25, June 17, 2025.Wir präsentieren eine metallfreie Methode für die Deuteriummarkierung von Aromaten in deuteriertem HFIP. Dieser Ansatz nutzt die erhöhte Basizität von Aromaten im angeregten Zustand, um den selektiven Wasserstoffisotopenaustausch an schwer zugänglichen Positionen zu ermöglichen.
Eva Rivera‐Chao +5 more
wiley +1 more source
La double vie de la sérotonine ou quand la génétique découvre la physiologie
, 2010 Durant les vingt dernières années, l’émergence d’outils génétiques sophistiqués a permis d’approfondir notre connaissance d’un grand nombre de fonctions physiologiques et d’en découvrir de nouvelles.
Gérard Karsenty, Franck Oury
core +1 more source
Genome-wide association studies in suicidology — analysis of main results
Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева, 2019 Studies of suicide genetics can be divided into 3 periods: 1) period of classical methods of behavioral genetics; 2) candidate genes association studies, and 3) genome-wide association studies.
V. A. Rozanov +4 more
doaj +1 more source
Aquaculture, Fish and Fisheries, Volume 5, Issue 3, June 2025.ABSTRACT Aeromonas hydrophila, an omnipresent bacterium that infects a wide range of hosts, is responsible for massive mortality and significant financial losses among farm‐raised fish species. To control bacterial diseases in aquaculture systems, inappropriate antibiotic therapy is commonly practised, leading to the development of antibiotic‐resistant
Alokesh Kumar Ghosh +2 more
wiley +1 more source