Results 51 to 60 of about 6,037 (161)

Identification of potentially causative drugs associated with hypotension: A scoping review

open access: yesArchiv der Pharmazie, Volume 358, Issue 1, January 2025.
Antihypertensives are just the tip of the iceberg of drugs that cause hypotension. This scoping review examines antihypertensive and nonantihypertensive drugs associated with hypotension, analysing 97 studies from 2013 to 2023. It examines the frequency of reporting and corresponding levels of evidence and evaluates the results taking into account ...
Nurunnisa Sari   +2 more
wiley   +1 more source

Un silence imparfait. Femmes, d\ue9pression mentale et naturalisation de l'exp\ue9rience (Carnia, ann\ue9es 1990) [PDF]

open access: yes, 2015
Prenant appui sur une recherche de deux ans men\ue9e dans un centre de sant\ue9 mentale du nord-est d\u2019Italie, cet article souhaite approcher la d\ue9pression par une pluralit\ue9 de points de vue : celui du savoir scientifique qui a naturalis\ue9 la
Cozzi, Donatella
core  

Bivalent and bitopic ligands of the opioid receptors: The prospects of a dual approach

open access: yesMedicinal Research Reviews, Volume 44, Issue 6, Page 2545-2599, November 2024.
Abstract Opioid receptors belonging to the class A G‐protein coupled receptors (GPCRs) are the targets of choice in the treatment of acute and chronic pain. However, their on‐target side effects such as respiratory depression, tolerance and addiction have led to the advent of the ‘opioid crisis’.
Marie Emilie Hovah, Ulrike Holzgrabe
wiley   +1 more source

The role of serotonin in depression—A historical roundup and future directions

open access: yesJournal of Neurochemistry, Volume 168, Issue 9, Page 1751-1779, September 2024.
Although depression has been studied for many decades, the exact mechanisms that lead to depression are still unknown, and available treatments only help a fraction of patients. In the 1960s, the serotonin hypothesis was published, suggesting that serotonin is the key player in depression. However, this hypothesis is being increasingly doubted. In this
Svenja Bremshey   +3 more
wiley   +1 more source

Estimation of digestible tryptophan:lysine ratios for maximum performance, egg quality and welfare of white-egg-laying hens by fitting the different non-linear models

open access: yesJournal of Applied Animal Research, 2018
A total of 360 Hy-Line W-36 hens at 30 wk of age were assigned to 6 dietary treatments that consisted of 6 different (11, 15, 19, 23, 27 and 31) digestible Trp:Lys ratios. Hens were fed the experimental diets from 30 to 36 wk of age.
S. N. Mousavi   +3 more
doaj   +1 more source

Does vitamin D supplementation impact serotonin levels? A systematic review and meta‐analysis

open access: yesHealth Science Reports, Volume 7, Issue 8, August 2024.
Abstract Background and Aims Vitamin D deficiency impacts a significant proportion of the world's population, and this deficiency has been linked to various conditions characterized by imbalanced serotonin regulation. The objective of this systematic review and meta‐analysis was to evaluate the effect of vitamin D supplementation on serum serotonin ...
Malek Alimohammadi‐Kamalabadi   +11 more
wiley   +1 more source

Medication and supplement pharmacokinetic changes following bariatric surgery: A systematic review and meta‐analysis

open access: yesObesity Reviews, Volume 25, Issue 8, August 2024.
Summary Objectives To evaluate the impact of bariatric surgery on the pharmacokinetic (PK) parameters of orally administered medications and supplements. Methods Systematic searches of bibliographic databases were conducted to identify studies. Pooled effect estimates from different surgical procedures were calculated using a random‐effects model ...
Fannie Lajeunesse‐Trempe   +16 more
wiley   +1 more source

QSAR–CoMSIA applied to antipsychotic drugs with their dopamine D2 and serotonine 5HT2A membrane receptors [PDF]

open access: yesJournal of the Serbian Chemical Society, 2011
Antipsychotic drugs are psychiatric medication primarily used to manage psychosis (e.g., delusions or hallucinations), particularly in schizophrenia and bipolar disorder.
SPERANTA AVRAM   +3 more
doaj  

Increased urinary excretion of kynurenic acid is associated with non-recovery from acute kidney injury in critically ill patients

open access: yesBMC Nephrology, 2018
Background Acute kidney injury (AKI) is often observed in critically ill patients and is associated with high morbidity and mortality. Non-recovery from AKI has a negative impact on the prognosis of affected patients and early risk stratification seems ...
Fabienne Aregger   +6 more
doaj   +1 more source

Adaptive Reaktion bei der Lösung von flexiblen Molekülen: Oligohydrate von 4‐Hydroxy‐2‐butanon

open access: yesAngewandte Chemie, Volume 136, Issue 29, July 15, 2024.
Die schrittweise Hydratation eines flexiblen organischen Moleküls zeigt, wie Wassersolvatisierungsgerüste, im Allgemeinen über verschiedene Strukturwege, die Substratstruktur verformen. In diesem Experiment beobachteten wir mithilfe breitbandiger Mikrowellenspektroskopie die Solvatisierung von 4‐Hydroxy‐2‐butanon mit bis zu fünf Wassermolekülen.
Meng Li   +4 more
wiley   +1 more source

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