Results 51 to 60 of about 2,851 (147)

The role of serotonin in depression—A historical roundup and future directions

Journal of Neurochemistry, Volume 168, Issue 9, Page 1751-1779, September 2024.
Although depression has been studied for many decades, the exact mechanisms that lead to depression are still unknown, and available treatments only help a fraction of patients. In the 1960s, the serotonin hypothesis was published, suggesting that serotonin is the key player in depression. However, this hypothesis is being increasingly doubted. In this
Svenja Bremshey, Juliana Groß, Kim Renken, Olivia Andrea Masseck   +3 more
wiley   +1 more source

QSAR–CoMSIA applied to antipsychotic drugs with their dopamine D2 and serotonine 5HT2A membrane receptors [PDF]

Journal of the Serbian Chemical Society, 2011
Antipsychotic drugs are psychiatric medication primarily used to manage psychosis (e.g., delusions or hallucinations), particularly in schizophrenia and bipolar disorder.
SPERANTA AVRAM, DANIEL DUDA-SEIMAN, FLORIN BORCAN, PETER WOLSCHANN   +3 more
doaj  

EVALUATION OF ORAL PREGABALIN IN TREATMENT OF PREMATURE EJACULATION [PDF]

Zagazig University Medical Journal, 2019
Background: Premature ejaculation (PE) is the most common form of male sexual dysfunction. Treatment modalities include behavioral therapy and medical therapy. No therapy is approved by the FDA for treatment of PE.
Mohamed Al-Naggar, Abdulrahman Hashem, Mohamed EL Hariri   +2 more
doaj   +1 more source

Does vitamin D supplementation impact serotonin levels? A systematic review and meta‐analysis

Health Science Reports, Volume 7, Issue 8, August 2024.
Abstract Background and Aims Vitamin D deficiency impacts a significant proportion of the world's population, and this deficiency has been linked to various conditions characterized by imbalanced serotonin regulation. The objective of this systematic review and meta‐analysis was to evaluate the effect of vitamin D supplementation on serum serotonin ...
Malek Alimohammadi‐Kamalabadi, Somayeh Ziaei, Motahareh Hasani, Shooka Mohammadi, Milad Mehrbod, Mehrnaz Morvaridi, Emma Persad, Andrej Belančić, Mahsa Malekahmadi, Maria Dulce da Mota Antunes de Oliveira Estêvão, Elnaz Daneshzad, Javad Heshmati   +11 more
wiley   +1 more source

A Novel Dopamine Transporter Inhibitor CE-123 Improves Cognitive Flexibility and Maintains Impulsivity in Healthy Male Rats

Frontiers in Behavioral Neuroscience, 2017
Reduced cognitive abilities are often characterized by an impairment of flexibility, i.e., the ability to switch from learned rules or categories that were important in certain contexts to different new modalities that rule the task.
Agnieszka Nikiforuk, Predrag Kalaba, Marija Ilic, Volker Korz, Vladimir Dragačević, Judith Wackerlig, Thierry Langer, Harald Höger, Joanna Golebiowska, Piotr Popik, Gert Lubec   +10 more
doaj   +1 more source

Medication and supplement pharmacokinetic changes following bariatric surgery: A systematic review and meta‐analysis

Obesity Reviews, Volume 25, Issue 8, August 2024.
Summary Objectives To evaluate the impact of bariatric surgery on the pharmacokinetic (PK) parameters of orally administered medications and supplements. Methods Systematic searches of bibliographic databases were conducted to identify studies. Pooled effect estimates from different surgical procedures were calculated using a random‐effects model ...
Fannie Lajeunesse‐Trempe, Dominika Okroj, Eduard Ostarijas, Alan Ramalho, Eve‐Julie Tremblay, David Llewellyn, Chris Harlow, Nikhil Chandhyoke, Nicholas W. S. Chew, Royce P. Vincent, Andre Tchernof, Marie‐Eve Piché, Paul Poirier, Laurent Biertho, Marie‐Philippe Morin, Caroline S. Copeland, Georgios K. Dimitriadis   +16 more
wiley   +1 more source

Comparison of the groups treated with mirtazapine and selective serotonine reuptake inhibitors with respect to birth outcomes and severity of psychiatric disorder

Psychiatry and Clinical Psychopharmacology, 2019
Objective: The literature provides very limited information on mirtazapine usage in the pregnancy period. The groups including pregnant women who used SSRI or mirtazapine as a single treatment, SSRI–mirtazapine combination treatment and unmedicated ...
Buket Belkız Güngör, Nalan Öztürk, Ayça Öngel Atar, Nazan Aydın   +3 more
doaj   +1 more source

Effect of Fermentation, Drying and Roasting on Biogenic Amines and Other Biocompounds in Colombian Criollo Cocoa Beans and Shells

Foods, 2020
The composition of microbiota and the content and pattern of bioactive compounds (biogenic amines, polyphenols, anthocyanins and flavanols), as well as pH, color, antioxidant and reducing properties were investigated in fermented Criollo cocoa beans and ...
Johannes Delgado-Ospina, Carla Daniela Di Mattia, Antonello Paparella, Dino Mastrocola, Maria Martuscelli, Clemencia Chaves-Lopez   +5 more
doaj   +1 more source

Adaptive Reaktion bei der Lösung von flexiblen Molekülen: Oligohydrate von 4‐Hydroxy‐2‐butanon

Angewandte Chemie, Volume 136, Issue 29, July 15, 2024.
Die schrittweise Hydratation eines flexiblen organischen Moleküls zeigt, wie Wassersolvatisierungsgerüste, im Allgemeinen über verschiedene Strukturwege, die Substratstruktur verformen. In diesem Experiment beobachteten wir mithilfe breitbandiger Mikrowellenspektroskopie die Solvatisierung von 4‐Hydroxy‐2‐butanon mit bis zu fünf Wassermolekülen.
Meng Li, Wenqin Li, Cristóbal Pérez, Alberto Lesarri, Jens‐Uwe Grabow   +4 more
wiley   +1 more source

Dietary phytase and myo-inositol supplementation are associated with distinct plasma metabolome profile in broiler chickens

Animal, 2020
Phytase enzyme is used as a dietary supplement in broiler nutrition to improve phosphorous bioavailability. Phytase deliberates phosphate groups from phytic acid and produces myo-inositol after total dephosphorylation.
F. Gonzalez-Uarquin, Á. Kenéz, M. Rodehutscord, K. Huber   +3 more
doaj   +1 more source