Results 1 to 10 of about 6,500 (140)

Case Report: Dose-dependent response to oclacitinib in a dog with Sézary syndrome [PDF]

open access: yesFrontiers in Veterinary Science
Cutaneous epitheliotropic T-cell lymphoma (CETL) is a rare malignant canine skin tumor. Sézary syndrome, a rare and aggressive subtype of CETL, lacks established treatment guidelines in veterinary medicine.
Jungmin Lym   +8 more
doaj   +2 more sources

Unusual presentation of fungal keratitis and endogenous endophthalmitis in Sézary syndrome: a case report [PDF]

open access: yesAmerican Journal of Ophthalmology Case Reports
Purpose: This report describes an atypical presentation of Candida keratitis and subsequent endogenous bacterial endophthalmitis in a patient with Sézary Syndrome undergoing immunotherapy and subsequently chemotherapy. Observations: A male patient in his
Marta Fernández-Gurría   +3 more
doaj   +2 more sources

Real-life efficacy of immunotherapy for Sézary syndrome: a multicenter observational cohort studyResearch in context [PDF]

open access: yesEClinicalMedicine
Summary: Background: Sézary syndrome is an extremely rare and fatal cutaneous T-cell lymphoma (CTCL). Mogamulizumab, an anti-CCR4 monoclonal antibody, has recently been associated with increased progression-free survival in a randomized clinical trial ...
Alizée Bozonnat   +47 more
doaj   +2 more sources

HDAC10 and its implications in Sézary syndrome pathogenesis [PDF]

open access: yesFrontiers in Cell and Developmental Biology
Cutaneous T-cell lymphomas (CTCL) are a group of rare hematological malignancies characterized by infiltration of malignant T-cells into the skin. Two main types of CTCL constitute of Mycosis Fungoides (MF), a more indolent form of the disease, and ...
Monika Pieniawska   +17 more
doaj   +2 more sources

Bilateral peripheral ulcerative keratitis in a patient with known Sézary syndrome [PDF]

open access: yesAmerican Journal of Ophthalmology Case Reports
Purpose: To report a case of bilateral peripheral ulcerative keratitis (PUK) in a patient with underlying Sézary syndrome. Observations: A 58-year-old male presented with bilateral corneal ulceration with stromal thinning and was diagnosed with PUK.
Michael J. Maywood   +2 more
doaj   +2 more sources

Dupilumab-associated sezary syndrome

open access: yesIndian Journal of Dermatology, 2023
Dupilumab is a monoclonal antibody that inhibits interleukin-4 (IL-4) and interleukin-13 (IL-13), approved for the treatment of adults with moderate-to-severe atopic dermatitis (AD).
Austin Hamp   +3 more
doaj   +2 more sources

Mycosis fungoides and Sézary syndrome

open access: yeshealthbook TIMES. Oncology Hematology, 2021
Mycosis fungoides (MF) and Sézary syndrome (SS) are two subgroups of cutaneous T-cell lymphomas (CTCL), which belong to the extranodal non-Hodgkin lymphomas. These are rare diseases whose etiology is still not fully understood.
Ieva Saulite   +2 more
doaj   +2 more sources

Single-cell RNA-sequencing reveals predictive features of response to pembrolizumab in Sézary syndrome

open access: yesOncoImmunology, 2022
The PD-1 inhibitor pembrolizumab is effective in treating Sézary syndrome, a leukemic variant of cutaneous T-cell lymphoma. Our purpose was to investigate the effects of pembrolizumab on healthy and malignant T cells in Sézary syndrome and to discover ...
Tianying Su   +6 more
doaj   +1 more source

Sézary Syndrome with CD4/CD8 Double-Negative Neoplastic T Cells in Peripheral Blood

open access: yesCase Reports in Hematology, 2021
Sézary syndrome is a rare leukemic type of cutaneous T-cell lymphoma characterized by the presence of neoplastic T cells with cerebriform nuclei (Sézary cells) in the skin, lymph nodes, and peripheral blood.
Yuki Kageyama   +6 more
doaj   +1 more source

Difficult diagnostics of a rare cause of pulmonary hypertension: a case report

open access: yesРоссийский кардиологический журнал, 2021
Pulmonary hypertension is a syndrome difficult for differential diagnosis, which is the outcome of various pathological conditions. With the exclusion of the most common causes of pulmonary hypertension (left heart disorders and pulmonary embolism ...
N. V. Kizhvatova   +3 more
doaj   +1 more source

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