Results 11 to 20 of about 6,519 (158)

Delayed Diagnosis of Sézary Syndrome: Lessons From a Psoriasiform Presentation. [PDF]

open access: yesClin Case Rep
ABSTRACT Pruritic erythroderma is not always psoriasis. Resistant cases require a broad evaluation for cutaneous lymphoma. Early, timely diagnosis prevents disease progression, improves outcomes, and enhances quality of life, highlighting the need for re‐evaluation when conventional treatments fail.
Neupane S, Neupane A, Khan SA, Kausar H.
europepmc   +2 more sources

Survival and Prognostic Factors in Patients with Aggressive Cutaneous T-cell Lymphomas

open access: yesActa Dermato-Venereologica, 2022
Aggressive primary cutaneous T-cell lymphomas include advanced-stage mycosis fungoides (stage ≥ IIB mycosis fungoides), Sézary syndrome, gamma/delta cutaneous lymphoma, nasal type lymphoma, aggressive epidermotropic CD8+ T-cell lymphoma and some ...
Joséphine Franceschi   +6 more
doaj   +1 more source

A High Programmed Cell Death Protein 1 Hormone Receptor Score on Skin Biopsy is Associated with Sézary Syndrome Diagnosis: A Study of 91 Patients with Erythroderma

open access: yesActa Dermato-Venereologica, 2022
Erythroderma is challenging to diagnose. The aim of this single-centre retrospective study was to identify factors that can be used to improve the diagnosis of erythroderma.
Camille Luherne   +10 more
doaj   +1 more source

Benefit/risk Ratio of Low-dose Methotrexate in Cutaneous Lesions of Mycosis Fungoides and Sézary Syndrome

open access: yesActa Dermato-Venereologica, 2021
Low-dose methotrexate is widely used in mycosis fungoides and Sézary syndrome, but few studies have evaluated this treatment. The aim of this study was to evaluate the benefit/risk ratio of this regimen on skin lesions. A retrospective survey of a series
Fawaz Alenezi   +5 more
doaj   +1 more source

Validation of AAC-11-Derived Peptide Anti-Tumor Activity in a Single Graft Sézary Patient-Derived Xenograft Mouse Model

open access: yesCells, 2022
Sézary syndrome (SS) is an aggressive cutaneous T cell lymphoma with poor prognosis mainly characterized by the expansion of a tumor CD4+ T cell clone in both skin and blood.
Justine Habault   +6 more
doaj   +1 more source

Molecular genetic features of cutaneous T-cell lymphomas development on example of mycosis fungoides and Sezary syndrome

open access: yesОнкогематология, 2022
Cutaneous T-cell lymphomas are a heterogeneous group of T-cell lymphoproliferative diseases affecting the skin. Mycosis fungoides and Sezary syndrome are the most studied variants of them.
M. B. Khadzhieva   +5 more
doaj   +1 more source

Loss of the candidate tumor suppressor ZEB1 (TCF8, ZFHX1A) in Sézary syndrome [PDF]

open access: yes, 2018
Cutaneous T-cell lymphoma is a group of incurable extranodal non-Hodgkin lymphomas that develop from the skin-homing CD4+ T cell. Mycosis fungoides and Sézary syndrome are the most common histological subtypes.
Benucci, Roberto   +9 more
core   +2 more sources

No genetic evidence for involvement of Deltaretroviruses in adult patients with precursor and mature T-cell neoplasms [PDF]

open access: yes, 2007
Background The Deltaretrovirus genus comprises viruses that infect humans (HTLV), various simian species (STLV) and cattle (BLV). HTLV-I is the main causative agent in adult T-cell leukemia in endemic areas and some of the simian T-cell lymphotropic ...
Burmeister, Thomas   +4 more
core   +2 more sources

Transcript-indexed ATAC-seq for precision immune profiling. [PDF]

open access: yes, 2018
T cells create vast amounts of diversity in the genes that encode their T cell receptors (TCRs), which enables individual clones to recognize specific peptide-major histocompatibility complex (MHC) ligands. Here we combined sequencing of the TCR-encoding
Buenrostro, Jason D   +21 more
core   +1 more source

Blood and skin-derived Sezary cells: differences in proliferation-index, activation of PI3K/AKT/mTORC1 pathway and its prognostic relevance [PDF]

open access: yes, 2019
Sézary syndrome (SS) is a rare and aggressive variant of Cutaneous T-Cell Lymphoma characterized by neoplastic distribution mainly involving blood, skin, and lymph-node.
Benucci, Roberto   +15 more
core   +1 more source

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