Results 11 to 20 of about 5,029 (162)
Sézary Syndrome with CD4/CD8 Double-Negative Neoplastic T Cells in Peripheral Blood
Case Reports in Hematology, 2021 Sézary syndrome is a rare leukemic type of cutaneous T-cell lymphoma characterized by the presence of neoplastic T cells with cerebriform nuclei (Sézary cells) in the skin, lymph nodes, and peripheral blood.
Yuki Kageyama +6 more
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Survival and Prognostic Factors in Patients with Aggressive Cutaneous T-cell Lymphomas
Acta Dermato-Venereologica, 2022 Aggressive primary cutaneous T-cell lymphomas include advanced-stage mycosis fungoides (stage ≥ IIB mycosis fungoides), Sézary syndrome, gamma/delta cutaneous lymphoma, nasal type lymphoma, aggressive epidermotropic CD8+ T-cell lymphoma and some ...
Joséphine Franceschi +6 more
doaj +1 more source
Acta Dermato-Venereologica, 2022 Erythroderma is challenging to diagnose. The aim of this single-centre retrospective study was to identify factors that can be used to improve the diagnosis of erythroderma.
Camille Luherne +10 more
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Acta Dermato-Venereologica, 2021 Low-dose methotrexate is widely used in mycosis fungoides and Sézary syndrome, but few studies have evaluated this treatment. The aim of this study was to evaluate the benefit/risk ratio of this regimen on skin lesions. A retrospective survey of a series
Fawaz Alenezi +5 more
doaj +1 more source
Cells, 2022 Sézary syndrome (SS) is an aggressive cutaneous T cell lymphoma with poor prognosis mainly characterized by the expansion of a tumor CD4+ T cell clone in both skin and blood.
Justine Habault +6 more
doaj +1 more source
Targeting Epigenetic Modifiers Can Reduce the Clonogenic Capacities of Sézary Cells
Frontiers in Oncology, 2021 Sézary syndrome (SS) is an aggressive leukemic variant of cutaneous T-cell lymphomas (CTCL) in which the human Telomerase Reverse Transcriptase (hTERT) gene is re-expressed. Current available treatments do not provide long-term response.
Alain Chebly +14 more
doaj +1 more source
Alemtuzumab in refractory Sézary syndrome [PDF]
Anais Brasileiros de Dermatologia, 2016 : Sézary syndrome is a primary cutaneous T-cell lymphoma characterized by the triad of erythroderma, lymphadenopathy and circulating atypical cells. The emergence of new molecular targets has enabled the development of drugs such as alemtuzumab, an anti ...
Carmen María Alcántara Reifs +5 more
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The MicroRNA Expression Profile Differs Between Erythrodermic Mycosis Fungoides and Sézary Syndrome
Acta Dermato-Venereologica, 2019 It is difficult to distinguish erythrodermic mycosis fungoides from Sézary syndrome due to their similar clinical and histological features. The main purpose of this study was to investigate whether microRNA expression profiles in lesional skin could ...
Anne Hald Rittig +6 more
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Anais Brasileiros de Dermatologia, 2012 This paper reviews the diagnostic and classificatory concepts of mycosis fungoides and Sézary syndrome in light of the latest normative publications. It describes the great variability of the clinical expression of mycosis fungoides in its early stages ...
Thamy Yamashita +3 more
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Poor prognostic factors of Sézary syndrome: A retrospective single‐center study from Japan
Journal of Cutaneous Immunology and Allergy, 2022 Objectives Although the prognosis of Sézary syndrome (SS) is highly unfavorable, the prognostic factors have not been fully understood. In this study, we tried to investigate the prognostic factors in Japanese SS patients for the first time.
Yuka Mizuno +11 more
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