Results 31 to 40 of about 6,519 (158)

Alemtuzumab in refractory Sézary syndrome [PDF]

Anais Brasileiros de Dermatologia, 2016
: Sézary syndrome is a primary cutaneous T-cell lymphoma characterized by the triad of erythroderma, lymphadenopathy and circulating atypical cells. The emergence of new molecular targets has enabled the development of drugs such as alemtuzumab, an anti ...
Carmen María Alcántara Reifs, Rafael Salido-Vallejo, Gloria María Garnacho-Saucedo, Sofía De la Corte-Sánchez, Alberto González-Menchen, Antonio Vélez García-Nieto   +5 more
doaj   +1 more source

Targeting Epigenetic Modifiers Can Reduce the Clonogenic Capacities of Sézary Cells

Frontiers in Oncology, 2021
Sézary syndrome (SS) is an aggressive leukemic variant of cutaneous T-cell lymphomas (CTCL) in which the human Telomerase Reverse Transcriptase (hTERT) gene is re-expressed. Current available treatments do not provide long-term response.
Alain Chebly, Alain Chebly, Martina Prochazkova-Carlotti, Yamina Idrissi, Laurence Bresson-Bepoldin, Sandrine Poglio, Chantal Farra, Chantal Farra, Marie Beylot-Barry, Marie Beylot-Barry, Jean-Philippe Merlio, Jean-Philippe Merlio, Roland Tomb, Roland Tomb, Edith Chevret   +14 more
doaj   +1 more source

A mouse model for the Sézary syndrome

Journal of Experimental & Clinical Cancer Research, 2010
Background The Sézary syndrome is an aggressive leukemic form of cutaneous T cell lymphoma and there is no cure of this disease. Until now there is no true animal model for Sézary syndrome, by which new drugs against the disease could be tested.
Doebbeling Udo
doaj   +1 more source

Diagnostic and therapeutic considerations in idiopathic hypereosinophilia with warm autoimmune hemolytic anemia. [PDF]

, 2015
Hypereosinophilic syndrome (HES) encompasses numerous diverse conditions resulting in peripheral hypereosinophilia that cannot be explained by hypersensitivity, infection, or atopy and that is not associated with known systemic diseases with specific ...
Brys, Adam K, Sheth, Milan R, Sohn, David D, Sweidan, Alexander J   +3 more
core   +1 more source

Síndrome de Sézary.

Acta Médica Portuguesa, 1998
Sézary syndrome is a form of cutaneous T-cell lymphoma and, like mycosis fungoides, results from the malignant proliferation of mature post-thymic T-cell lymphocytes.
F Ferreira, T M Correia, L Callabro, J Andrade   +3 more
doaj   +1 more source

Sèzary Syndrome-A Rarely Seen Variant of Non-Hodgkins Lymphoma [PDF]

National Journal of Laboratory Medicine, 2020
Cutaneous T-Cell Lymphomas (CTCL) is a group of T-Cell Non-Hodgkin’s Lymphomas, originating from T-cells of skin associated lymphoid tissue. Mycosis fungoides is a specific type of CTCL derived from CD4+T-cells.
Premila De Sousa Rocha, Rajika S Bhat, Neha Da Rocha, Roque Gabriel Wiseman Pinto   +3 more
doaj   +1 more source

Childhood hypopigmented mycosis fungoides: a commonly delayed diagnosis [PDF]

, 2014
Primary cutaneous lymphomas (PCLs) are exceedingly rare in children and adolescents, with mycosis fungoides (MF) being the most frequent PCL diagnosed in childhood. There are numerous unusual clinical variants of MF, including the hypopigmented type form
Gameiro, A, Gouveia, M, Moreno, A, Tellechea, O   +3 more
core   +1 more source

Increase of DC-LAMP+ mature dendritic cell subsets in dermatopathic lymphadenitis of mycosis fungoides [PDF]

, 2014
Background: Little is known about the immunological milieu of the skin-draining lymph nodes (LNs) in mycosis fungoides (MF). Objectives: We studied dendritic cell (DC) subsets in the dermatopathic lymphadenitis of MF patients.
Aoyama, Yumi, Asagoe, Kenji, Hamada, Toshihisa, Iwatsuki, Keiji, Mizuno-Ikeda, Kazuko, Otsuka, Masaki, Tada, Kotaro, Umemura, Hiroshi, Yamasaki, Osamu   +8 more
core   +1 more source

Gene Expression Comparison between Sézary Syndrome and Lymphocytic-Variant Hypereosinophilic Syndrome Refines Biomarkers for Sézary Syndrome

Cells, 2020
Sézary syndrome (SS), an aggressive cutaneous T-cell lymphoma (CTCL) with poor prognosis, is characterized by the clinical hallmarks of circulating malignant T cells, erythroderma and lymphadenopathy. However, highly variable clinical skin manifestations
Andrea Moerman-Herzog, Syed J. Mehdi, Henry K. Wong   +2 more
doaj   +1 more source

THE TREATMENT OF ADVANCED-STAGE MYCOSIS FUNGOIDES AND SEZARY SYNDROME: A HEMATOLOGIST'S POINT OF VIEW.

Mediterranean Journal of Hematology and Infectious Diseases, 2022
Cutaneous T-cell lymphomas are a heterogenous group of T-cell neoplasms involving the skin, the majority of which may be classified as Mycosis Fungoides (MF) or Sézary Syndrome (SS).
Antonio Giordano, Livio Pagano
doaj   +1 more source