Results 31 to 40 of about 5,029 (162)

Síndrome de Sézary em cadela Sézary syndrome in a bitch

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2007
The present report describes a case of Sezary syndrome in a canine with lymphadenomegaly, generalized erithroderma, intense pruritus and disseminated cutaneous nodules and plaques.
S.M. Rodigheri, M.R. Farias, J. Werner, T.R. Macedo, M.A.B. Ostrowski   +4 more
doaj   +1 more source

Enhancement of antibody-dependent cellular cytotoxicity is associated with treatment response to extracorporeal photopheresis in Sézary syndrome

OncoImmunology, 2021
Sézary syndrome (SS) is a rare, leukemic type of cutaneous T-cell lymphoma (CTCL), for which extracorporeal photopheresis (ECP) is a first-line therapy. Reliable biomarkers to objectively monitor the response to ECP in patients with SS are missing.
Christoph Iselin, Yun-Tsan Chang, Tanja Schlaepfer, Christina Fassnacht, Florentia Dimitriou, Mirjam Nägeli, Steve Pascolo, Wolfram Hoetzenecker, Malgorzata Bobrowicz, Emmanuella Guenova   +9 more
doaj   +1 more source

Pruritus Is an Indicator for Quality of Life in Cutaneous T‐Cell Lymphoma

The Journal of Dermatology, EarlyView.
ABSTRACT In cutaneous T‐cell lymphoma (CTCL), chronic pruritus affects up to 94% of patients as a leading factor reducing quality of life (QoL). Traditional antipruritic medication does not show sufficient relief. Partly due to a lack of therapeutic options, pruritus is rarely assessed in a standardized manner within routine clinical practice.
Andrea Roggo, Yves Wüest, Reinhard Dummer, Egle Ramelyte   +3 more
wiley   +1 more source

Large‐cell transformation of mycosis fungoides: Patterns of care and patient outcomes

British Journal of Haematology, EarlyView.
Large‐cell transformation of mycosis fungoides is rare with poor prognosis. Presenting over 20 years of data, this retrospective study of 83 patients demonstrated a median overall survival (mOS) of 3.5 years. However, prognostic differences in three clinical subgroups were suggested: unifocal, multifocal, extra‐cutaneous (mOS: 4.6, 2.5, 1.1 years ...
Philippa Johnstone, Martin Higgins, H. Miles Prince, Stephen Lade, Chris McCormack, Carrie van der Weyden, Friyana Bhabha, Odette Buelens, Piers Blombery, Belinda A. Campbell   +9 more
wiley   +1 more source

Nasal Dysbiosis in Cutaneous T-Cell Lymphoma Is Characterized by Shifts in Relative Abundances of Non-Staphylococcus Bacteria

JID Innovations, 2022
The nasal microbiome of patients with cutaneous T-cell lymphoma (CTCL) remains unexplored despite growing evidence connecting nasal bacteria to skin health and disease.
Madeline J. Hooper, Tessa M. LeWitt, Francesca L. Veon, Yanzhen Pang, George E. Chlipala, Leo Feferman, Stefan J. Green, Dagmar Sweeney, Katherine T. Bagnowski, Michael B. Burns, Patrick C. Seed, Joan Guitart, Xiaolong A. Zhou   +12 more
doaj  

Novel and recurrent histopathologic patterns of mogamulizumab‐associated rash: diagnostic implications and insights for accurate diagnosis

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background Mogamulizumab‐associated rash (MAR) is a frequent side‐effect of a treatment with Mogamulizumab that poses diagnostic challenges. Patients and methods We reviewed our database for novel histological patterns in MAR. Results Four new histological patterns were identified: (1) A pagetoid pattern, which could be mistaken for CD8 ...
Christina Mitteldorf
wiley   +1 more source

Cutaneous T-cell lymphoma: Differential diagnostics of erythrodermic conditions

Vestnik Dermatologii i Venerologii, 2019
Erythroderma is a condition damaging at least 80–90 % of the skin surface, characterized by erythema and peeling. This condition may be a manifestation of various diseases of the skin and internal organs, including malignant lymphoproliferative disorders.
A. E. Karamova, V. V. Chikin, L. F. Znamenskaya, A. A. Vorontsova   +3 more
doaj   +1 more source

The PNH French Working Group Experience: Building a Strong Network of Cytometrists

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction The PNH working group was created in 2010 to initiate a workshop on testing white blood cells to share international recommendations. Methods Thirty‐five French and Belgian laboratories equipped with 2‐ or 3‐laser cytometers applied three different panels with or without FLAER reagent in 305 samples.
Orianne Wagner‐Ballon, Magali Le Garff‐Tavernier, Rémi Lestestu, Bernard Drenou, Agathe Debliquis, the PNH French Working Group «CytHem‐HPN», Chantal Fossat, Claire Loosen, Bernard Chatelain, Marie Loosveld   +9 more
wiley   +1 more source

Effectiveness and safety of methotrexate in the treatment of mycosis fungoides: Real‐world data from a multicentre study

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Methotrexate (MTX) has been a longstanding therapeutic option for mycosis fungoides (MF); however, data on its real‐world effectiveness remain limited. This study aimed to assess real‐world outcomes of oral MTX in the treatment of MF. Data from five referral centres for cutaneous lymphoma in Greece were retrospectively reviewed with the baseline‐ and ...
Vasiliki Nikolaou, Evdoxia Panou, Antonios Tsimpidakis, Ioannis‐Alexios Koumprentziotis, Aikaterini Patsatsi, Marina Siakantaris, Sabine‐Elke Kruger‐Krasagakis, Leonidas Marinos, Elisavet Georgiou, Kyriaki Lampadaki, Aliki Velissari, Athina‐Ioanna Daponte, Aikaterini Doxastaki, Stella Kaliampou, Aristeidis Vaiopoulos, Iliana Konstandinou, Marios Koumourtzis, Eleftheria Lakiotaki, Vassiliki Pappa, Athanasios Tsamaldoupis, Alexander Stratigos, Evangelia Papadavid   +21 more
wiley   +1 more source

Low-dose intermittent alemtuzumab in the treatment of Sézary syndrome: clinical and immunologic findings in 14 patients

Haematologica, 2007
Background and Objectives Alemtuzumab may be effective in Sézary syndrome (SS), an aggressive cutaneous T-cell lymphoma, but is associated with severe hematologic toxicity and infections.
Maria Grazia Bernengo, Pietro Quaglino, Alessandra Comessatti, Michela Ortoncelli, Mauro Novelli, Francesco Lisa, Maria Teresa Fierro   +6 more
doaj   +1 more source