Results 61 to 70 of about 6,519 (158)

Prognostic significance of endogenous adhesion/growth-regulatory lectins in lung cancer [PDF]

, 2005
Objective: To determine the expression of endogenous adhesion/growth-regulatory lectins and their binding sites using labeled tissue lectins as well as the binding profile of hyaluronic acid as an approach to define new prognostic markers.
Akos Horvath, Andre S, Andre S, Andre S, Andre S, Andre S, Arnusch CJ, Buttery R, Elad-Sfadia G, Gabius HJ, Gabius HJ, Gabius HJ, Hans-Joachim Gabius, Imre Trojan, Jan-Dirk Baumhäkel, Jozsef Furak, Kaltner H, Kayser K, Kayser K, Kayser K, Kayser K, Klaus Kayser, Kopitz J, Kornelia Szluha, Lahm H, Laszlo Tiszlavicz, Liu FT, Moon BK, Nangia-Makker P, Puglisi F, Rappl G, Rorive S, Sabine Andre, Sheikholeslam-Zadeh R, Siebert HC, Tamas Szöke   +35 more
core   +1 more source

Suppressive CD8+ T‐Cells Are Key Cellular Mediators of Extracorporeal Photopheresis

Journal of Clinical Apheresis, Volume 41, Issue 1, February 2026.
ABSTRACT Extracorporeal photopheresis (ECP) is a widely utilized immunomodulatory procedure with an incompletely defined mechanism. In graft‐versus‐host disease (GvHD) and transplant rejection, ECP is thought to induce immune tolerance by increasing regulatory CD4+ T‐cells, whereas in cutaneous T cell lymphoa it may enhance dendritic cell–mediated ...
Kai J. Rogers, Kathryn L. Eschbacher, Zeb Zacharias, Kshitija Kale, Michael P. Crawford, Charles Michael Knudson, Alexander W. Boyden, Nitin J. Karandikar   +7 more
wiley   +1 more source

Erupção a fármaco com eosinofilia e sintomas sistémicos (síndrome dress) [PDF]

, 2008
Adverse cutaneous reactions to drugs are frequent, affecting from 2% to 3% of all hospitalized patients. But only about 2% of these cutaneous reactions are severe and seldom are fatal. The term drug hypersensitivity syndrome refers to a specific severe
Ferreira, M., Lobo, I., Sanches, M., Selores, M., Velho, G.   +4 more
core  

Staphylococcal enterotoxin A (SEA) stimulates STAT3 activation and IL-17 expression in cutaneous T-cell lymphoma [PDF]

, 2016
Cutaneous T-cell lymphoma (CTCL) is characterized by proliferation of malignant T cells in a chronic inflammatory environment. With disease progression, bacteria colonize the compromised skin barrier and half of CTCL patients die of infection rather than
Abrahmsén, Anders Woetmann, Andreas Willerslev-Olsen, Aschebrook-Kilfoy, Axelrod, Baser, Boniface, Bonin, Brender, Brender, Bromberg, Carsten Geisler, Charlotte M. Bonefeld, Choi, Chong, Cirée, Claudia Nastasi, David L. Petersen, Denis Sasseville, Doherty, Dulmage, Eriksen, Flex, Geisler, Girardi, Goel, Hodak, Huang, Ivan V. Litvinov, Jackow, Jahan-Tigh, James, Kaltoft, Kaltoft, Kasprzycka, Kim, Kopp, Krejsgaard, Krejsgaard, Krejsgaard, Krejsgaard, Lars Iversen, Lee, Levidou, Linnemann, Lise M. Lindahl, Litvinov, Litvinov, Lynge, Mariusz A. Wasik, Marzec, McGirt, Mirvish, Mirvish, Miyagaki, Mogens Kilian, Morales-Suárez-Varela, Moreau, Muranski, Nguyen, Niels Odum, Nielsen, Nielsen, Nielsen, Nigel P. Mongan, Pinchuk, Posner, Qin, Robert Gniadecki, Sergei B. Koralov, Sibbesen, Simon Fredholm, Smoller, Sommer, Talpur, Thorbjørn Krejsgaard, Tokura, Tokura, van der Fits, van der Fits, van der Fits, van der Fits, van Kester, Verma, Vermeer, Vonderheid, Walters, Wilcox, Willemze, Willerslev-Olsen, Woetmann, Woetmann, Wolk, Zhang, Zhang   +94 more
core   +2 more sources

Primary Cutaneous Peripheral T‐Cell Lymphoma With Follicular Helper T‐Cell Phenotype

Journal of Cutaneous Pathology, Volume 53, Issue 2, Page 147-152, February 2026.
ABSTRACT An otherwise healthy 82‐year‐old woman presented with recurrent, asymptomatic erythematous papulo‐nodular lesions on the face and extremities. A skin biopsy revealed a dense, non‐epidermotropic lymphohistiocytic infiltrate with granulomatous features and a mixed population of medium‐sized atypical lymphoid cells and plasma cells ...
Nidia Planella‐Fontanillas, Andrea Molina‐Alvarez, Lluís Colomo‐Saperas, Roger Rovira, Monica Gonzàlez‐Farré, Carlos Barranco‐Sanz, Xavier Calvo, Clara Nadal‐Pellisé, Fernando Gallardo, Ramon M. Pujol   +9 more
wiley   +1 more source

The Prognostic Value of ТР53 Gene Mutations in Patients with Cutaneous T-Cell Lymphomas

Клиническая онкогематология
BACKGROUND. Primary cutaneous lymphomas represent a heterogeneous group of neoplastic diseases with unique clinical, immunomorphological, and molecular genetic features.
Liliya Gamilevna Gorenkova, B. V. Biderman, A. K. Smolianinova, E. E. Zvonkov   +3 more
doaj   +1 more source

The role of 9-O-acetylated ganglioside D3 (CD60) and α4β1 (CD49d) expression in predicting the survival of patients with Sézary syndrome

Haematologica, 2010
Background Sézary syndrome is a rare and very aggressive leukemic variant of cutaneous T-cell lymphoma characterized by extensive skin involvement and a malignant circulating CD4+ T-cell clone which homes to the skin, over-expresses CD60, and lacks CD7 ...
Enrico Scala, Damiano Abeni, Debora Pomponi, Maria Grazia Narducci, Giuseppe Alfonso Lombardo, Adriano Mari, Marina Frontani, Maria Cristina Picchio, Maria Antonietta Pilla, Elisabetta Caprini, Giandomenico Russo   +10 more
doaj   +1 more source

Granulomatous rosacea: Like leukemid in a patient with acute myeloid leukemia [PDF]

, 2008
Introduction. Skin findings in leukemias may be divided into specific lesions (leukemia cutis) and non-specific lesions (leukemids) which may be found in up to 80% of all patients with leukemias.
Bogatić Dragana, Medenica Ljiljana, Popadić Svetlana, Čolović Milica, Škiljević Dušan   +4 more
core   +1 more source

CRISPR‐Cas9 screen reveals that inhibition of enhancer of zeste homolog 2 sensitizes malignant T cells to dimethyl‐fumarate‐induced cell death

The FEBS Journal, Volume 293, Issue 3, Page 749-765, February 2026.
A genome‐wide CRISPR‐Cas9 screen identified H3K27 methylation as a key regulator of T‐cell lymphoma sensitivity to dimethyl fumarate (DMF). Specifically, inhibition of enhancer of zeste homolog 2 (EZH2) enhanced DMF‐induced cell death in malignant T cells. These results provide functional evidence for the role of EZH2 in modulating drug sensitivity and
Jan P. Teubner, Deniz Tümen, Arne Kandulski, Philipp Heumann, Patricia Mester, Elisabeth Aschenbrenner, Kirstin Pollinger, Manuela Gunckel, Barbara Volz, Tobias Hein, Paul L. Beltzig, Luisa Tengler, Florian Voll, Marina Kreutz, Claudia Kunst, Jan P. Nicolay, Martina Müller, Karsten Gülow   +17 more
wiley   +1 more source

Spectrum of mutational signatures in T-cell lymphoma reveals a key role for UV radiation in cutaneous T-cell lymphoma

Scientific Reports, 2021
T-cell non-Hodgkin’s lymphomas develop following transformation of tissue resident T-cells. We performed a meta-analysis of whole exome sequencing data from 403 patients with eight subtypes of T-cell non-Hodgkin’s lymphoma to identify mutational ...
Christine L. Jones, Andrea Degasperi, Vieri Grandi, Tauanne D. Amarante, Genomics England Research Consortium, Tracey J. Mitchell, Serena Nik-Zainal, Sean J. Whittaker   +7 more
doaj   +1 more source