White paper on best practices for translational research in neuroendocrine neoplasms. [PDF]
Abstract Basic and translational investigations play a crucial role in advancing our understanding of neuroendocrine neoplasms (NENs). In this white paper by the Basic and Translational Research Group of the European Neuroendocrine Tumor Society, we discuss the qualities and drawbacks of current disease models and propose good practices for integrating
Cros J +10 more
europepmc +2 more sources
Mucinous cystic neoplasms and simple mucinous cysts are two distinct precursors of pancreatic cancer: clinicopathological, genomic, and transcriptomic characterization. [PDF]
Abstract Mucinous cystic neoplasms (MCNs) of the pancreas are macroscopic precursors of pancreatic cancer. A similar cystic lesion but lacking the ovarian‐type subepithelial stroma has been recently defined as a simple mucinous cyst (SMC); however, its nature remains unclear. This study aims to define the clinicopathological and molecular profiles of a
Pea A +37 more
europepmc +2 more sources
Oncocytic and spindle cell typical carcinoids of lung: different immunophenotype and biological behavior. [PDF]
Abstract Pulmonary typical carcinoids (TCs) are uncommon, well‐differentiated neuroendocrine tumors of the lung that do not exhibit necrosis and have fewer than two mitoses per 2 mm2, as defined by the current World Health Organization classifications.
Sabella G +23 more
europepmc +2 more sources
Current technical advancements in plant epitranscriptomic studies
Abstract The growth and development of plants are the result of the interplay between the internal developmental programming and plant–environment interactions. Gene expression regulations in plants are made up of multi‐level networks. In the past few years, many studies were carried out on co‐ and post‐transcriptional RNA modifications, which ...
Yichun Xie +4 more
wiley +1 more source
Contribution of cultural heritage values to steppe conservation on ancient burial mounds of Eurasia
Abstract Civilizations, including ancient ones, have shaped global ecosystems in many ways through coevolution of landscapes and humans. However, the cultural legacies of ancient and lost civilizations are rarely considered in the conservation of the Eurasian steppe biome.
Balázs Deák +26 more
wiley +1 more source
Dialectics of Sign and Symbol and the Utterance of Archetype Theory
Abstract Debates surrounding Jung’s archetype theory could be characterized as tacit attempts to contend with the concept’s dual function as referring to something known to psychologists (sign) and standing for something that is fundamentally unknowable (symbol).
Raya Jones
wiley +1 more source
Ascl1, OTP, and Ki‐67 drive the clinical outcome of lung atypical carcinoids. Aims According to World Health Organization guidelines, atypical carcinoids (ACs) are well‐differentiated lung neuroendocrine tumours with 2–10 mitoses/2 mm2 and/or foci of necrosis (usually punctate). Besides morphological criteria, no further tools in predicting AC clinical
Giovanni Centonze +20 more
wiley +1 more source
Abstract This article examines the phrase “light from light” in the 4th‐century Nicene and Nicene‐Constantinopolitan creeds. The article begins by presenting the earliest use of light as a metaphor for Christ and his agency, as well as examples of similar language outside “orthodox” Christianity. It goes on to examine the meaning and use of “light from
Maria Munkholt Christensen
wiley +1 more source
Comparative quantitation of DNA water tracers using OptiQ, Qubit, and Nanodrop
Abstract We have recently developed new synthetic DNA tracers for tracking sources and pathways of contamination in surface water and groundwater. The use of DNA tracers in natural water systems results in substantial and rapid dilutions, thus accurate quantitation of initial DNA tracer concentrations applied is crucial to ensure their successful ...
Craig Billington +4 more
wiley +1 more source
Sustainability issues along the coffee chain: From the field to the cup
Abstract The coffee industry is one of the most important commercial value chains worldwide. Nonetheless, it is also associated to several social, economic, and environmental concerns that impair its sustainability. The present review is focused on these main sustainability concerns from the field to the coffee cup, as well as on the strategies that ...
Juliana A. Barreto Peixoto +3 more
wiley +1 more source

