Results 1 to 10 of about 21,093,248 (119)

Formulation and evaluation of s-(-)-amlodipine besylate and nebivolol hydrochloride tablets. [PDF]

J Adv Pharm Technol Res, 2010
The objective of the present study was to develop a tablet formulation of S-(-)-amlodipine besylate chiral separation drug and nebivolol hydrochloride for better management of hypertension, while reducing or avoiding undesirable adverse effects, which are often associated with administration of a racemic mixture of amlodipine.
Shaikh SA, Shaikh SS, Shahi SR, Shookur MA, Reddy LK, Padalkar AN, Thube M.   +6 more
europepmc   +8 more sources

Development and Evaluation of a Modified Fixed-Dose Combination Antihypertensive Tablet Containing S-Amlodipine Besylate: A Bioequivalence and Stability Study. [PDF]

Pharmaceutics
Background/Objectives: Fixed-dose combination (FDC) antihypertensive medications containing olmesartan medoxomil, amlodipine besylate, and hydrochlorothiazide are widely used for the treatment of essential hypertension. Although effective, the use of racemic amlodipine, which contains both active S(−)-amlodipine and inactive R(+)-amlodipine, has been ...
Moon HW, Jeong JH, Park CW.
europepmc   +4 more sources

Association of Concomitant Amlodipine Use With Serum Olanzapine Concentrations and Clinical Outcomes in Patients With Schizophrenia. [PDF]

Hum Psychopharmacol
ABSTRACT Objective To examine whether concomitant amlodipine use was associated with steady‐state serum olanzapine concentration and clinical outcomes in patients with schizophrenia. Methods This retrospective study included 45 inpatients with schizophrenia and hypertension who received olanzapine 10 mg/day plus amlodipine 5 mg/day (experimental group)
Chen X, Ma J, Xuan X, Huang M, Yang X, Huang B.   +5 more
europepmc   +2 more sources

Effects of Two Allisartan Isoproxil-Based Antihypertensive Therapies on Sexual Function and Blood Pressure in Male Hypertensive Patients: A Single-Center, Open-Label, and Randomized Controlled Trial. [PDF]

J Clin Hypertens (Greenwich)
ABSTRACT This study evaluated the effects of allisartan isoproxil combined with amlodipine besylate tablets (Group A+C) or metoprolol succinate extended‐release tablets (Group A+B) on sexual function and nighttime blood pressure (nBP) in 130 male patients with essential hypertension (EH). Patients were randomized to two groups.
Wang M, Chen J, Qi M, Sun R, Long Z, Su Q, Mou Y, Liu H, Wang Q, Wu Q, Zhang X, Yu J.   +11 more
europepmc   +2 more sources

Design-Assisted Chemometric UV Spectrophotometric Determination of Candesartan Cilexetil, Chlorthalidone and Amlodipine Using Principal Component Regression, Partial Least Squares and Genetic Algorithm-Partial Least Squares Models. [PDF]

Anal Sci Adv
ABSTRACT This study presents a sustainable chemometric‐assisted UV spectrophotometric strategy for the simultaneous determination of candesartan cilexetil (CAN), chlorthalidone (CTL) and amlodipine (AML) in laboratory‐prepared mixtures and commercial pharmaceutical formulations.
Amin KFM, Elagamy SH, Obaydo RH, Lotfy HM.   +3 more
europepmc   +2 more sources

Antihypertensive Efficacy, Safety, and Adherence After Switching From a Free Combination of Bisoprolol/Metoprolol and Amlodipine to Bisoprolol/Amlodipine FDC Tablets (5/5 mg) in Chinese Patients With Hypertension. [PDF]

J Clin Hypertens (Greenwich)
ABSTRACT Hypertension is a leading chronic disease globally, with rising prevalence in China. A considerable number of hypertension patients struggle to achieve target blood pressure levels with monotherapy alone. The bisoprolol/amlodipine FDC shows promise for blood pressure control and adherence, whereas clinical evidence for Chinese patients is ...
Wang N, Zhou X, Han J, Jiang J, Ma L, Liu G, Liu R, Kong Y, Tang Y, Jiang W, Wei Y, Cheng W.   +11 more
europepmc   +2 more sources

Cyclodextrins as Chiral Selectors in Capillary Electrophoresis-Recent Developments in Understanding Analyte Complexation and Applications in Pharmaceutical Analysis. [PDF]

Electrophoresis
Cyclodextrins are the most often applied chiral selectors in CE enantioseparations. In combination with NMR spectroscopy and molecular modeling, studies for an understanding of chiral recognition underlying enantioseparations have been performed.
Scriba GKE.
europepmc   +2 more sources

Use of Forced Degradation Studies on S-(−)-Amlodipine Besylate to Generate Information on the Degradation Products [PDF]

Scientia Pharmaceutica, 2010
Amlodipine is a long-acting calcium channel blocker used in the treatment of hypertension and angina pectoris. [...]
openaire   +1 more source

Effect of hydrophilic and hydrophobic polymers on permeation of S-amlodipine besylate through intercalated polymeric transdermal matrix: 3(2) designing, optimization and characterization

Drug Development and Industrial Pharmacy, 2019
Objective: Innovation in material science has made it possible to fabricate a pharmaceutical material of modifiable characteristics and utility, in delivering therapeutics at a sustained/controlled rate. The objective of this study is to design and optimize the controlled release transdermal films of S-Amlodipine besylate by intercalating hydrophilic ...
Vaibhav Rastogi, Pragya Yadav, Arif Husain, Anurag Verma   +3 more
openaire   +2 more sources

ANALYTICAL METHOD DEVELOPMENT FOR ESTIMATION OF S (-) AMLODIPINE BESYLATE & OLMESARTAN MEDOXOMIL BY UV SPECTROSCOPY

, 2023
For simultaneous estimation of S (-) amlodipine besylate & olmesartan medoxomil, the simple, accurate, precise, reproducible and economic UV spectroscopic methods have been developed. The method A-Area Under curve method, method B- Absorption ratio method and method C- Dual wavelength method were developed by using JASCO double beam UV ...
openaire   +2 more sources