Results 161 to 170 of about 25,478 (242)

Recent advances in the structure, function and regulation of the volume‐regulated anion channels and their role in immunity

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The volume‐regulated anion channel (VRAC), composed of leucine‐rich repeat‐containing 8 (LRRC8) proteins, serves both canonical and non‐canonical functions in vertebrate cells. The canonical function of this channel relates to its original description, which is homeostatic regulation of cell volume in response to hypotonic ...
Sergei Yanushkevich   +9 more
wiley   +1 more source

FLOT1 Is a Novel Serum Biomarker of Ovarian Cancer Targeted by N6‐methyladenosine Modification Inhibition

open access: yesCell Biology International, Volume 49, Issue 6, Page 674-691, June 2025.
ABSTRACT Ovarian cancer (OC) is a deadly disease and lacks a precise marker for diagnosis worldwide. Our previous work has shown the overexpression of flotillin‐1 (FLOT1) in OC tissue. To improve diagnostic sensitivity and accuracy, we evaluated the serum level of FLOT1 in OC patients and found that the serum concentration of FLOT1 as well as CA125 was
Bin Guan   +7 more
wiley   +1 more source

Transcription factor GTF2I regulates osteoclast differentiation through mediating miR‐134‐5p and MAT2A expressions

open access: yesJournal of Cell Communication and Signaling, Volume 19, Issue 2, June 2025.
Abstract This study explored the possible effect of transcription factor GTF2I on the differentiation of osteoclasts and its regulation on the miR‐134‐5p/MAT2A axis. RANKL‐induced osteoclasts were measured for expressions of GTF2I, miR‐134‐5p, and MAT2A. The number and size of osteoclasts were assessed after TRAP staining. The expressions of osteoclast
Lian Tang   +5 more
wiley   +1 more source

THE FORMATION OF S-ADENOSYLMETHIONINE IN YEAST

open access: yesJournal of Biological Chemistry, 1957
F. Schlenk, R.E. DePalma
openaire   +3 more sources

Gut‐derived Lactobacillus from exceptional responders mitigates chemoradiotherapy‐induced intestinal injury through methionine‐driven epigenetic modulation

open access: yesiMeta, Volume 4, Issue 3, June 2025.
Using metagenomic sequencing and bioinformatics analysis of fecal samples from rectal cancer patients and corresponding mouse models, our study identifies a strong association between Lactobacillus abundance and acute chemoradiotherapy‐induced intestinal injury (ACRIII). Elevated Lactobacillus levels before treatment were consistently linked to reduced
Lu Yu   +16 more
wiley   +1 more source

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